J Biomed Inform - OWL-based reasoning methods for validating archetypes.

Tópicos

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{ take(945) account(800) differ(722) }
{ general(901) number(790) one(736) }
{ data(1714) softwar(1251) tool(1186) }
{ method(2212) result(1239) propos(1039) }
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{ health(3367) inform(1360) care(1135) }
{ first(2504) two(1366) second(1323) }
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{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ intervent(3218) particip(2042) group(1664) }
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{ can(981) present(881) function(850) }
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{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ use(1733) differ(960) four(931) }
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{ method(1969) cluster(1462) data(1082) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Some modern Electronic Healthcare Record (EHR) architectures and standards are based on the dual model-based architecture, which defines two conceptual levels: reference model and archetype model. Such architectures represent EHR domain knowledge by means of archetypes, which are considered by many researchers to play a fundamental role for the achievement of semantic interoperability in healthcare. Consequently, formal methods for validating archetypes are necessary. In recent years, there has been an increasing interest in exploring how semantic web technologies in general, and ontologies in particular, can facilitate the representation and management of archetypes, including binding to terminologies, but no solution based on such technologies has been provided to date to validate archetypes. Our approach represents archetypes by means of OWL ontologies. This permits to combine the two levels of the dual model-based architecture in one modeling framework which can also integrate terminologies available in OWL format. The validation method consists of reasoning on those ontologies to find modeling errors in archetypes: incorrect restrictions over the reference model, non-conformant archetype specializations and inconsistent terminological bindings. The archetypes available in the repositories supported by the openEHR Foundation and the NHS Connecting for Health Program, which are the two largest publicly available ones, have been analyzed with our validation method. For such purpose, we have implemented a software tool called Archeck. Our results show that around 1/5 of archetype specializations contain modeling errors, the most common mistakes being related to coded terms and terminological bindings. The analysis of each repository reveals that different patterns of errors are found in both repositories. This result reinforces the need for making serious efforts in improving archetype design processes.

Resumo Limpo

modern electron healthcar record ehr architectur standard base dual modelbas architectur defin two conceptu level refer model archetyp model architectur repres ehr domain knowledg mean archetyp consid mani research play fundament role achiev semant interoper healthcar consequ formal method valid archetyp necessari recent year increas interest explor semant web technolog general ontolog particular can facilit represent manag archetyp includ bind terminolog solut base technolog provid date valid archetyp approach repres archetyp mean owl ontolog permit combin two level dual modelbas architectur one model framework can also integr terminolog avail owl format valid method consist reason ontolog find model error archetyp incorrect restrict refer model nonconform archetyp special inconsist terminolog bind archetyp avail repositori support openehr foundat nhs connect health program two largest public avail one analyz valid method purpos implement softwar tool call archeck result show around archetyp special contain model error common mistak relat code term terminolog bind analysi repositori reveal differ pattern error found repositori result reinforc need make serious effort improv archetyp design process

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