J Biomed Inform - Oscillabolastic model, a new model for oscillatory dynamics, applied to the analysis of Hes1 gene expression and Ehrlich ascites tumor growth.

Tópicos

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Resumo

This paper introduces a new dynamical model, called the oscillabolastic model, to analyze the dynamical behavior of biomedical data when one observes oscillatory behavior. The proposed oscillabolastic model is sufficiently flexible to represent various types of oscillatory behavior. The oscillabolastic model is applied to two sets of data. The first data set deals with the oscillabolastic modeling of Ehrlich ascites tumor cells and the second one is the oscillabolastic modeling of the mean signal intensity of Hes1 gene expression in response to serum stimulation. A generalized oscillabolastic model is also suggested to accommodate cases in which predictor variables other than time are also involved.

Resumo Limpo

paper introduc new dynam model call oscillabolast model analyz dynam behavior biomed data one observ oscillatori behavior propos oscillabolast model suffici flexibl repres various type oscillatori behavior oscillabolast model appli two set data first data set deal oscillabolast model ehrlich ascit tumor cell second one oscillabolast model mean signal intens hes gene express respons serum stimul general oscillabolast model also suggest accommod case predictor variabl time also involv

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