J Biomed Inform - Authoring and verification of clinical guidelines: a model driven approach.

Tópicos

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Resumo

JECTIVES: The goal of this research is to provide a framework to enable authoring and verification of clinical guidelines. The framework is part of a larger research project aimed at improving the representation, quality and application of clinical guidelines in daily clinical practice.METHODS: The verification process of a guideline is based on (1) model checking techniques to verify guidelines against semantic errors and inconsistencies in their definition, (2) combined with Model Driven Development (MDD) techniques, which enable us to automatically process manually created guideline specifications and temporal-logic statements to be checked and verified regarding these specifications, making the verification process faster and cost-effective. Particularly, we use UML statecharts to represent the dynamics of guidelines and, based on this manually defined guideline specifications, we use a MDD-based tool chain to automatically process them to generate the input model of a model checker. The model checker takes the resulted model together with the specific guideline requirements, and verifies whether the guideline fulfils such properties.RESULTS: The overall framework has been implemented as an Eclipse plug-in named GBDSSGenerator which, particularly, starting from the UML statechart representing a guideline, allows the verification of the guideline against specific requirements. Additionally, we have established a pattern-based approach for defining commonly occurring types of requirements in guidelines. We have successfully validated our overall approach by verifying properties in different clinical guidelines resulting in the detection of some inconsistencies in their definition.CONCLUSIONS: The proposed framework allows (1) the authoring and (2) the verification of clinical guidelines against specific requirements defined based on a set of property specification patterns, enabling non-experts to easily write formal specifications and thus easing the verification process.

Resumo Limpo

jectiv goal research provid framework enabl author verif clinic guidelin framework part larger research project aim improv represent qualiti applic clinic guidelin daili clinic practicemethod verif process guidelin base model check techniqu verifi guidelin semant error inconsist definit combin model driven develop mdd techniqu enabl us automat process manual creat guidelin specif temporallog statement check verifi regard specif make verif process faster costeffect particular use uml statechart repres dynam guidelin base manual defin guidelin specif use mddbase tool chain automat process generat input model model checker model checker take result model togeth specif guidelin requir verifi whether guidelin fulfil propertiesresult overal framework implement eclips plugin name gbdssgener particular start uml statechart repres guidelin allow verif guidelin specif requir addit establish patternbas approach defin common occur type requir guidelin success valid overal approach verifi properti differ clinic guidelin result detect inconsist definitionconclus propos framework allow author verif clinic guidelin specif requir defin base set properti specif pattern enabl nonexpert easili write formal specif thus eas verif process

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