J Clin Monit Comput - Changes in cardiac output and stroke volume as measured by non-invasive CO monitoring in infants with RSV bronchiolitis.

Tópicos

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Resumo

JECTIVES: The primary aim of the study was to determine the changes, if any, in cardiac output (CO) and stroke volume (SV) in normal infants with RSV bronchiolitis. The secondary aim was to determine whether changes in CO (CO) and SV (SV) are associated with changes in respiratory rate (RR).METHODS: Non-invasive CO recordings were obtained within 24 h of admission and discharge. Changes in CO, SV, and HR measurements were compared using paired t-tests. The effect of fluid boluses during the first 24 h (<60 or =60 cc/kg) on CO was assessed by 2 way ANOVA with time and group as main effect. The relationship between RR and CO or SV was assessed by linear regression. Data is presented as Mean ? SEM and mean differences with 95 % confidence interval (p < 0.05 considered significant).RESULTS: 15 infants with RSV bronchiolitis were studied. CO (1.31 ? 0.13 to 1.11 ? 0.11 l/min (0.21 [0.04-0.37]) and SV (9.42 ? 1.10 to 7.75 ? 0.83 ml/beat (1.67 [0.21-3.12]) decreased significantly while HR (142.1 ? 4.0 to 145.2 ? 3.1 beats/min 3.0 [-5.3 to 11.3]) was unchanged. SV (p = 0.02) and CO (p = 0.04) significantly decreased only in the 7 infants that received =60 cc/kg. RR correlated significantly with CO (r (2) = 0.28, p = 0.04); but not with SV (r (2) = 0.20, p = 0.09).CONCLUSIONS: CO was related to SV and not HR. The CO and SV were affected by fluid boluses. RR correlated with CO. Non-invasive CO monitoring can trend CO and SV in infants with bronchiolitis during hospitalization.

Resumo Limpo

jectiv primari aim studi determin chang cardiac output co stroke volum sv normal infant rsv bronchiol secondari aim determin whether chang co co sv sv associ chang respiratori rate rrmethod noninvas co record obtain within h admiss discharg chang co sv hr measur compar use pair ttest effect fluid bolus first h cckg co assess way anova time group main effect relationship rr co sv assess linear regress data present mean sem mean differ confid interv p consid significantresult infant rsv bronchiol studi co lmin sv mlbeat decreas signific hr beatsmin unchang sv p co p signific decreas infant receiv cckg rr correl signific co r p sv r p conclus co relat sv hr co sv affect fluid bolus rr correl co noninvas co monitor can trend co sv infant bronchiol hospit

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