J Clin Monit Comput - Bi-spectral index, entropy and predicted plasma propofol concentrations with target controlled infusions in Indian patients.


{ activ(1452) weight(1219) physic(1104) }
{ model(2220) cell(1177) simul(1124) }
{ compound(1573) activ(1297) structur(1058) }
{ state(1844) use(1261) util(961) }
{ survey(1388) particip(1329) question(1065) }
{ measur(2081) correl(1212) valu(896) }
{ assess(1506) score(1403) qualiti(1306) }
{ signal(2180) analysi(812) frequenc(800) }
{ use(976) code(926) identifi(902) }
{ clinic(1479) use(1117) guidelin(835) }
{ model(2341) predict(2261) use(1141) }
{ use(2086) technolog(871) perceiv(783) }
{ decis(3086) make(1611) patient(1517) }
{ motion(1329) object(1292) video(1091) }
{ control(1307) perform(991) simul(935) }
{ blood(1257) pressur(1144) flow(957) }
{ patient(2837) hospit(1953) medic(668) }
{ first(2504) two(1366) second(1323) }
{ time(1939) patient(1703) rate(768) }
{ imag(1947) propos(1133) code(1026) }
{ imag(1057) registr(996) error(939) }
{ sequenc(1873) structur(1644) protein(1328) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ chang(1828) time(1643) increas(1301) }
{ general(901) number(790) one(736) }
{ howev(809) still(633) remain(590) }
{ import(1318) role(1303) understand(862) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ group(2977) signific(1463) compar(1072) }
{ activ(1138) subject(705) human(624) }
{ result(1111) use(1088) new(759) }
{ implement(1333) system(1263) develop(1122) }
{ process(1125) use(805) approach(778) }
{ model(3404) distribut(989) bayesian(671) }
{ can(774) often(719) complex(702) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ bind(1733) structur(1185) ligand(1036) }
{ method(1219) similar(1157) match(930) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ studi(2440) review(1878) systemat(933) }
{ treatment(1704) effect(941) patient(846) }
{ framework(1458) process(801) describ(734) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ data(1714) softwar(1251) tool(1186) }
{ design(1359) user(1324) use(1319) }
{ care(1570) inform(1187) nurs(1089) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ visual(1396) interact(850) tool(830) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ research(1218) medic(880) student(794) }
{ medic(1828) order(1363) alert(1069) }
{ cost(1906) reduc(1198) effect(832) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ intervent(3218) particip(2042) group(1664) }
{ patient(1821) servic(1111) care(1106) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ estim(2440) model(1874) function(577) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }


JECTIVE: Many processed electroencephalographic signals are used now to help the anaesthesiologist titrate the depth of sedation. We investigated the relationship between target plasma propofol concentration and objective end-points of sedation- Bispectral Index (BIS), State Entropy (SE) and Response Entropy (RE)-at clinical end-points as assessed by Modified Observer Assessment of Alertness/sedation Scale (MOAAS) in Indian patients.METHODS: Eighteen ASA 1 and 2 Indian adult patients scheduled to undergo elective surgery were included. The target control infusion (TCI) of propofol was administered using 'Diprifusor'. The level of sedation was assessed using MOAAS by the anaesthesiologist. BIS, SE, RE were recorded throughout. TCI was started at 0.5??g/ml and increased by 0.5??g/ml every 6?min till MOAAS scores reached 0 or there was sustained BIS value less than 30.RESULTS: The EC(50) and EC(95) of predicted plasma propofol concentration for loss of consciousness (assessed by loss of response to verbal command), were 2.3 and 2.8??g/ml respectively and for loss of response to painful stimuli (trapezius squeeze) were 4.0 and 5.0??g/ml respectively. The BIS and entropy values (EC(50) and EC(95)) for loss of consciousness and response to painful stimuli in Indian patients were estimated. The preliminary relation of target plasma propofol concentration with BIS was found to be BIS?=?100.5-16.4?(Target concentration).CONCLUSIONS: The target plasma propofol concentrations required to produce unconsciousness and loss of response to painful stimuli in Indian patients have been estimated. Also, the relations between target plasma concentration and objective measures of different levels of anaesthesia have been established.

Resumo Limpo

jectiv mani process electroencephalograph signal use now help anaesthesiologist titrat depth sedat investig relationship target plasma propofol concentr object endpoint sedat bispectr index bis state entropi se respons entropi reat clinic endpoint assess modifi observ assess alertnesssed scale moaa indian patientsmethod eighteen asa indian adult patient schedul undergo elect surgeri includ target control infus tci propofol administ use diprifusor level sedat assess use moaa anaesthesiologist bis se re record throughout tci start gml increas gml everi min till moaa score reach sustain bis valu less result ec ec predict plasma propofol concentr loss conscious assess loss respons verbal command gml respect loss respons pain stimuli trapezius squeez gml respect bis entropi valu ec ec loss conscious respons pain stimuli indian patient estim preliminari relat target plasma propofol concentr bis found bistarget concentrationconclus target plasma propofol concentr requir produc unconsci loss respons pain stimuli indian patient estim also relat target plasma concentr object measur differ level anaesthesia establish

Resumos Similares

J. Med. Internet Res. - How accurate is web-based self-reported height, weight, and body mass index in young adults? ( 0,60394609048722 )
Comput. Aided Surg. - Non-invasive computer-assisted measurement of knee alignment. ( 0,589483118918894 )
J. Med. Internet Res. - Validity of web-based self-reported weight and height: results of the Nutrinet-Sant? study. ( 0,581324195234403 )
J. Med. Internet Res. - Measuring physical activity in a cardiac rehabilitation population using a smartphone-based questionnaire. ( 0,569992384176833 )
Int J Health Geogr - Correspondence between objective and perceived walking times to urban destinations: Influence of physical activity, neighbourhood walkability, and socio-demographics. ( 0,556741359460109 )
J. Med. Internet Res. - Measures of physical activity using cell phones: validation using criterion methods. ( 0,55121562702361 )
J Med Syst - Barriers to physical activity: a study of self-revelation in an online community. ( 0,54523762545259 )
J Chem Inf Model - Quantifying the fingerprint descriptor dependence of structure-activity relationship information on a large scale. ( 0,535087339897387 )
Comput. Biol. Med. - CoMFA QSAR models of camptothecin analogues based on the distinctive SAR features of combined ABC, CD and E ring substitutions. ( 0,533370869549964 )
J Chem Inf Model - Structural determinants of drug partitioning in n-hexadecane/water system. ( 0,533079263866834 )
Med Decis Making - Estimating a preference-based index from the Clinical Outcomes in Routine Evaluation-Outcome Measure (CORE-OM): valuation of CORE-6D. ( 0,532155345515518 )
Comput Math Methods Med - Relationship between concentration difference of different density lipoproteins and shear stress in atherosclerosis. ( 0,530354476237412 )
Comput Math Methods Med - Influence of different geometric representations of the volume conductor on nerve activation during electrical stimulation. ( 0,52508442441462 )
J. Med. Internet Res. - Pain-QuILT: clinical feasibility of a web-based visual pain assessment tool in adults with chronic pain. ( 0,523502339881257 )
Comput. Aided Surg. - Computer-assisted measurements of coronal knee joint laxity in vitro are related to low-stress behavior rather than structural properties of the collateral ligaments. ( 0,521522144703733 )
Comput Math Methods Med - Disease control through voluntary vaccination decisions based on the smoothed best response. ( 0,520978057391097 )
J Chem Inf Model - Conditional probabilities of activity landscape features for individual compounds. ( 0,517831312445731 )
Int J Neural Syst - Phase synchronization of neuronal noise in mouse hippocampal epileptiform dynamics. ( 0,515596363546045 )
J. Med. Internet Res. - Estimation of physical activity levels using cell phone questionnaires: a comparison with accelerometry for evaluation of between-subject and within-subject variations. ( 0,513404322971678 )
J Med Syst - Direct numerical simulation of single leukocyte deformation in microchannel flow for disease diagnosis. ( 0,51318720313972 )
J. Med. Internet Res. - Broad reach and targeted recruitment using Facebook for an online survey of young adult substance use. ( 0,508435302941239 )
Int J Health Geogr - Evaluation of the neighborhood environment walkability scale in Nigeria. ( 0,508097706704752 )
J Chem Inf Model - Consensus ranking approach to understanding the underlying mechanism with QSAR. ( 0,504587669652252 )
J. Med. Internet Res. - Comparison of physical activity measures using mobile phone-based CalFit and Actigraph. ( 0,499915561934718 )
J Am Med Inform Assoc - An assessment of pharmacists' readiness for paperless labeling: a national survey. ( 0,499881672843122 )
Med Biol Eng Comput - 3D dynamic position assessment of the coronary sinus lead in cardiac resynchronization therapy. ( 0,499326363806779 )
AMIA Annu Symp Proc - ReadySteady: app for accelerometer-based activity monitoring and wellness-motivation feedback system for older adults. ( 0,497446703128308 )
J. Med. Internet Res. - The impact of an incentive on the use of an online self-directed wellness and self-management program. ( 0,497099197156356 )
Comput. Biol. Med. - Blood glucose level reconstruction as a function of transcapillary glucose transport. ( 0,495149074758858 )
Med Biol Eng Comput - Can common adhesion molecules and microtopography affect cellular elasticity? A combined atomic force microscopy and optical study. ( 0,490566044007065 )
J. Med. Internet Res. - Two new meal- and web-based interactive food frequency questionnaires: validation of energy and macronutrient intake. ( 0,490490973269738 )
J Chem Inf Model - Identification of non-macrocyclic small molecule inhibitors against the NS3/4A serine protease of hepatitis C virus through in silico screening. ( 0,489058094828997 )
Med Decis Making - Australian Public Preferences for the Funding of New Health Technologies: A Comparison of Discrete Choice and Profile Case Best-Worst Scaling Methods. ( 0,488471366527976 )
Health Info Libr J - Human information behaviour and physiological measurements as a basis to tailor health information. An explorative study in a physical activity intervention among prediabetic individuals in Northern Finland. ( 0,488422407165789 )
Med Biol Eng Comput - Change of mechanical vertebrae properties due to progressive osteoporosis: combined biomechanical and finite-element analysis within a rat model. ( 0,487592554531408 )
J Chem Inf Model - Discovery of novel selective serotonin reuptake inhibitors through development of a protein-based pharmacophore. ( 0,486347004111682 )
J. Med. Internet Res. - Evaluation of end-user satisfaction among employees participating in a web-based health risk assessment with tailored feedback. ( 0,486085681791524 )
J. Med. Internet Res. - How valid are Web-based self-reports of weight? ( 0,48500315951647 )
J Chem Inf Model - Pharmacophore-based virtual screening and experimental validation of novel inhibitors against cyanobacterial fructose-1,6-/sedoheptulose-1,7-bisphosphatase. ( 0,484676802965291 )
Inform Health Soc Care - A web-based intensive care clinical decision support system: from design to evaluation. ( 0,484429015926453 )
J. Med. Internet Res. - Web-based assessments of physical activity in youth: considerations for design and scale calibration. ( 0,48437959195898 )
Telemed J E Health - Barriers to telemedicine: survey of current users in acute care units. ( 0,4838237918999 )
J. Med. Internet Res. - Preparing facilitators from community-based organizations for evidence-based intervention training in Second Life. ( 0,480057624715946 )
J Clin Monit Comput - Reversal of neuromuscular blockade by sugammadex does not affect EEG derived indices of depth of anesthesia. ( 0,479740710248847 )
Telemed J E Health - Connecting to the future: telepsychiatry in postgraduate medical education. ( 0,478373206804097 )
J Chem Inf Model - Development of Ecom50 and retention index models for nontargeted metabolomics: identification of 1,3-dicyclohexylurea in human serum by HPLC/mass spectrometry. ( 0,478051055572603 )
Comput Math Methods Med - Antibiotic use as a tragedy of the commons: a cross-sectional survey. ( 0,478014626126906 )
Comput Methods Programs Biomed - Local identifiability and sensitivity analysis of neuromuscular blockade and depth of hypnosis models. ( 0,477790797450006 )
J. Med. Internet Res. - Web-based, computer-tailored, pedometer-based physical activity advice: development, dissemination through general practice, acceptability, and preliminary efficacy in a randomized controlled trial. ( 0,476221713061263 )
Comput. Biol. Med. - Prediction of stress shielding around an orthopedic screw: using stress and strain energy density as mechanical stimuli. ( 0,474938821586022 )
Med Biol Eng Comput - The effects of femoral neck cut, cable tension, and muscles forces on the greater trochanter fixation. ( 0,474168994345823 )
Sci Data - An open science resource for establishing reliability and reproducibility in functional connectomics. ( 0,473609675055445 )
Comput. Biol. Med. - Drug perfusion enhancement in tissue model by steady streaming induced by oscillating microbubbles. ( 0,472249452726195 )
Healthc (Amst) - Evaluation of readiness to transfer to adult healthcare: What about the well adolescent? ( 0,471855910329402 )
Med Biol Eng Comput - Pathologic deltoid activation in rotator cuff tear patients: normalization after cuff repair? ( 0,471448757127712 )
J. Med. Internet Res. - Mindless eating challenge: retention, weight outcomes, and barriers for changes in a public web-based healthy eating and weight loss program. ( 0,470566555041054 )
Comput Math Methods Med - Arthritic hand-finger movement similarity measurements: tolerance near set approach. ( 0,470408650001918 )
J Med Syst - Functional and mechanical evaluation of nerve stretch injury. ( 0,469851567619959 )
J. Med. Internet Res. - The establishment of an ethical guideline for genetic testing through citizen consensus via the Internet in Taiwan. ( 0,469012275839097 )
Appl Clin Inform - Development of a Decision Support Model for Screening Attention-deficit Hyperactivity Disorder with Actigraph-based Measurements of Classroom Activity. ( 0,468612874144264 )
Int J Med Inform - Motivating and assisting physical exercise in independently living older adults: a pilot study. ( 0,466809296334983 )
Comput. Biol. Med. - Estimation of the reliability of all-ceramic crowns using finite element models and the stress-strength interference theory. ( 0,465797130698512 )
Med Biol Eng Comput - In-silico modeling of atrial repolarization in normal and atrial fibrillation remodeled state. ( 0,465632364190307 )
J Telemed Telecare - Validity of a simple Internet-based outcome-prediction tool in patients with total hip replacement: a pilot study. ( 0,465524913910755 )
J Chem Inf Model - Discovery of new liver X receptor agonists by pharmacophore modeling and shape-based virtual screening. ( 0,46516047661624 )
BMC Med Inform Decis Mak - The SMART personalised self-management system for congestive heart failure: results of a realist evaluation. ( 0,464671959148236 )
J Chem Inf Model - Chemical structure elucidation from ??C NMR chemical shifts: efficient data processing using bipartite matching and maximal clique algorithms. ( 0,463956381549339 )
Med Biol Eng Comput - Experimentally validated three-dimensional finite element model of the rat for mild traumatic brain injury. ( 0,462910745641644 )
Int J Med Robot - A method for identifying otological drill milling through bone tissue wall. ( 0,462709097127616 )
J. Med. Internet Res. - Monitoring dietary intake and physical activity electronically: feasibility, usability, and ecological validity of a mobile-based Ecological Momentary Assessment tool. ( 0,46243659626737 )
Med Decis Making - Estimating the relative utility of screening mammography. ( 0,460750895205457 )
BMC Med Inform Decis Mak - The SAKK cancer-specific geriatric assessment (C-SGA): a pilot study of a brief tool for clinical decision-making in older cancer patients. ( 0,460467295347954 )
J Chem Inf Model - Experimentally validated HERG pharmacophore models as cardiotoxicity prediction tools. ( 0,460162890158147 )
Comput Methods Programs Biomed - Multifractal characterisation of electrocardiographic RR and QT time-series before and after progressive exercise. ( 0,460082488342651 )
J Chem Inf Model - Prediction of compounds with closely related activity profiles using weighted support vector machine linear combinations. ( 0,459302808505604 )
J Telemed Telecare - Use of telemedicine for haemodialysis in very remote areas: the Canadian First Nations. ( 0,459158154480796 )
Neural Comput - Risk-sensitive reinforcement learning. ( 0,45682445352973 )
J. Med. Internet Res. - Designing for psychological change: individuals' reward and cost valuations in weight management. ( 0,456651631477117 )
J Chem Inf Model - Introduction of the conditional correlated Bernoulli model of similarity value distributions and its application to the prospective prediction of fingerprint search performance. ( 0,455885081825681 )
Int J Comput Assist Radiol Surg - Influence of angulation on metacarpal bone mineral density measurements using digital X-ray radiogrammetry. ( 0,455478657977247 )
Comput Methods Programs Biomed - A patient specific electro-mechanical model of the heart. ( 0,454691520470076 )
J Telemed Telecare - A pilot teleconsultation network for retinal diseases in ophthalmology. ( 0,45439451899002 )
Comput Math Methods Med - Generic properties of curvature sensing through vision and touch. ( 0,452746256440744 )
Comput. Biol. Med. - Measuring the hypnotic depth of anaesthesia based on the EEG signal using combined wavelet transform, eigenvector and normalisation techniques. ( 0,452728932379505 )
Comput Methods Programs Biomed - Monitoring of anticoagulant therapy applying a dynamic statistical model. ( 0,452383240784281 )
Comput Math Methods Med - On the existence of wavelet symmetries in archaea DNA. ( 0,450740283496831 )
J. Med. Internet Res. - The use of physician-patient email: a follow-up examination of adoption and best-practice adherence 2005-2008. ( 0,450642618243228 )
J. Med. Internet Res. - An interactive internet-based plate for assessing lunchtime food intake: a validation study on male employees. ( 0,450178326548751 )
Comput Math Methods Med - In vivo imaging-based mathematical modeling techniques that enhance the understanding of oncogene addiction in relation to tumor growth. ( 0,45009156476301 )
Med Decis Making - Patient and societal value functions for the testing morbidities index. ( 0,449726428489263 )
Int J Med Robot - Coracoclavicular ligaments anatomical reconstruction: a feasibility study. ( 0,449641843630729 )
J Chem Inf Model - Normal mode analysis of Trp RNA binding attenuation protein: structure and collective motions. ( 0,44904158739249 )
Comput Methods Programs Biomed - Monte Carlo method for photon heating using temperature-dependent optical properties. ( 0,447883154407827 )
Int J Med Robot - Technical skills measurement based on a cyber-physical system for endovascular surgery simulation. ( 0,447244271742097 )
Int J Med Inform - Transitioning from a computerized provider order entry and paper documentation system to an electronic health record: expectations and experiences of hospital staff. ( 0,446880857733324 )
J. Med. Internet Res. - Classification accuracies of physical activities using smartphone motion sensors. ( 0,446760598413347 )
J. Med. Internet Res. - The change in eating behaviors in a Web-based weight loss program: a longitudinal analysis of study completers. ( 0,446673856928208 )
J Chem Inf Model - Identification of a novel inhibitor of dengue virus protease through use of a virtual screening drug discovery Web portal. ( 0,446060912722945 )
Comput. Biol. Med. - Permutation entropy analysis of vital signs data for outcome prediction of patients with severe traumatic brain injury. ( 0,445870519004593 )
J. Med. Internet Res. - Active-Q: validation of the web-based physical activity questionnaire using doubly labeled water. ( 0,445753098271579 )