J Clin Monit Comput - Evaluation of a computer program for non-invasive determination of pulmonary shunt and ventilation-perfusion mismatch.

Tópicos

{ error(1145) method(1030) estim(1020) }
{ model(2656) set(1616) predict(1553) }
{ method(1969) cluster(1462) data(1082) }
{ measur(2081) correl(1212) valu(896) }
{ method(1219) similar(1157) match(930) }
{ group(2977) signific(1463) compar(1072) }
{ high(1669) rate(1365) level(1280) }
{ blood(1257) pressur(1144) flow(957) }
{ sequenc(1873) structur(1644) protein(1328) }
{ chang(1828) time(1643) increas(1301) }
{ studi(1410) differ(1259) use(1210) }
{ cost(1906) reduc(1198) effect(832) }
{ model(3404) distribut(989) bayesian(671) }
{ can(774) often(719) complex(702) }
{ imag(2830) propos(1344) filter(1198) }
{ treatment(1704) effect(941) patient(846) }
{ design(1359) user(1324) use(1319) }
{ ehr(2073) health(1662) electron(1139) }
{ first(2504) two(1366) second(1323) }
{ use(976) code(926) identifi(902) }
{ data(1737) use(1416) pattern(1282) }
{ take(945) account(800) differ(722) }
{ motion(1329) object(1292) video(1091) }
{ assess(1506) score(1403) qualiti(1306) }
{ framework(1458) process(801) describ(734) }
{ care(1570) inform(1187) nurs(1089) }
{ method(984) reconstruct(947) comput(926) }
{ featur(1941) imag(1645) propos(1176) }
{ research(1085) discuss(1038) issu(1018) }
{ import(1318) role(1303) understand(862) }
{ studi(1119) effect(1106) posit(819) }
{ signal(2180) analysi(812) frequenc(800) }
{ patient(1821) servic(1111) care(1106) }
{ use(1733) differ(960) four(931) }
{ imag(1947) propos(1133) code(1026) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ featur(3375) classif(2383) classifi(1994) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ studi(2440) review(1878) systemat(933) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ problem(2511) optim(1539) algorithm(950) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ data(1714) softwar(1251) tool(1186) }
{ control(1307) perform(991) simul(935) }
{ model(2220) cell(1177) simul(1124) }
{ general(901) number(790) one(736) }
{ search(2224) databas(1162) retriev(909) }
{ case(1353) use(1143) diagnosi(1136) }
{ howev(809) still(633) remain(590) }
{ data(3963) clinic(1234) research(1004) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ system(1050) medic(1026) inform(1018) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ cancer(2502) breast(956) screen(824) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ implement(1333) system(1263) develop(1122) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

We describe a three-compartment model (shunt and two perfused compartments) to analyse the relationship between inspired oxygen (FIO2) and arterial oxygen saturation (SaO2) in terms of pulmonary shunt and ventilation-perfusion ratio (VA/Q). The program was tested using 24 exact datasets, each with six pairs of FIO2 and SaO2 data points with known VA/Q and shunt, generated by a complex calculator of gas exchange. Additional datasets were created by adding noise and rounding the exact sets, and by reducing the number of data points per dataset. The importance of the oxyhaemoglobin dissociation curve and the arterio-venous difference in oxygen content (avDO2) were also tested. Analysis using the three compartment model was more accurate than the two compartment model and less affected by data degradation. The absolute error in shunt estimation was never more than 2.2?% for the exact and rounded datasets, but the error in VA/Q estimation was -29 to 19?% of the true value (10th-90th centiles). The characteristics of the well-ventilated compartment were not determined accurately. At extremes of cardiac output, an assumed value of avDO2 resulted in significant errors. It is probably advantageous to correct for foetal haemoglobin in neonatal datasets. Analysis of FIO2 versus SaO2 datasets using a three compartment model provides accurate estimates of shunt and VA/Q when arterio-venous difference in oxygen content is known. The estimates may have value as objective measures of gas exchange, and as a visual guide for oxygen therapy.

Resumo Limpo

describ threecompart model shunt two perfus compart analys relationship inspir oxygen fio arteri oxygen satur sao term pulmonari shunt ventilationperfus ratio vaq program test use exact dataset six pair fio sao data point known vaq shunt generat complex calcul gas exchang addit dataset creat ad nois round exact set reduc number data point per dataset import oxyhaemoglobin dissoci curv arterioven differ oxygen content avdo also test analysi use three compart model accur two compart model less affect data degrad absolut error shunt estim never exact round dataset error vaq estim true valu thth centil characterist wellventil compart determin accur extrem cardiac output assum valu avdo result signific error probabl advantag correct foetal haemoglobin neonat dataset analysi fio versus sao dataset use three compart model provid accur estim shunt vaq arterioven differ oxygen content known estim may valu object measur gas exchang visual guid oxygen therapi

Resumos Similares

Int J Comput Assist Radiol Surg - Improved human observer performance in digital reconstructed radiograph verification in head and neck cancer radiotherapy. ( 0,66247894101635 )
J Chem Inf Model - Development of novel 3D-QSAR combination approach for screening and optimizing B-Raf inhibitors in silico. ( 0,647234595379451 )
Med Biol Eng Comput - Automatic video detection of body movement during sleep based on optical flow in pediatric patients with epilepsy. ( 0,642418512113622 )
J Clin Monit Comput - Evaluation of techniques for estimating the power spectral density of RR-intervals under paced respiration conditions. ( 0,632418426938973 )
Int J Comput Assist Radiol Surg - Optimized order estimation for autoregressive models to predict respiratory motion. ( 0,632112255623596 )
Comput. Biol. Med. - An effective measure for assessing the quality of biclusters. ( 0,62987697895975 )
Med Biol Eng Comput - Efficient and robust estimation of blood oxygenation levels in single cerebral veins. ( 0,629623831643064 )
Telemed J E Health - A new chest compression depth feedback algorithm for high-quality CPR based on smartphone. ( 0,622597149894116 )
Int J Comput Assist Radiol Surg - Wireless mobile technology to improve workflow and feasibility of MR-guided percutaneous interventions. ( 0,621654300409977 )
IEEE J Biomed Health Inform - A bicluster-based Bayesian principal component analysis method for microarray missing value estimation. ( 0,61694217318376 )
Comput Math Methods Med - Investigation of attenuation correction for small-animal single photon emission computed tomography. ( 0,615659254159699 )
IEEE Trans Image Process - t-Tests, F-tests and Otsu's methods for image thresholding. ( 0,614943774606658 )
Int J Comput Assist Radiol Surg - Mesh-based method for measuring intracranial volume in patients with craniosynostosis. ( 0,611939150008984 )
Methods Inf Med - Individual Thresholding of Voxel-based Functional Connectivity Maps. Estimation of Random Errors by Means of Surrogate Time Series. ( 0,609129712687033 )
Int J Comput Assist Radiol Surg - Three-dimensional prediction of free-flap volume in autologous breast reconstruction by CT angiography imaging. ( 0,608911198180635 )
J Chem Inf Model - Three useful dimensions for domain applicability in QSAR models using random forest. ( 0,601565278422902 )
Comput Methods Programs Biomed - Bayesian sample-size determination for two independent Poisson rates. ( 0,601242376075486 )
J Chem Inf Model - Conformational preferences of modified uridines: comparison of AMBER derived force fields. ( 0,596599615925502 )
Int J Comput Assist Radiol Surg - A morphological study of anatomical plates for acetabular posterior column. ( 0,59639279704267 )
Comput Methods Programs Biomed - Novel mathematical algorithm for pupillometric data analysis. ( 0,594336402847143 )
Comput Methods Programs Biomed - HELOW: a program for testing extreme homogeneity in meta-analysis. ( 0,586940478768587 )
Comput Methods Programs Biomed - Modeling the glucose regulatory system in extreme preterm infants. ( 0,582658714564426 )
J Chem Inf Model - Best of both worlds: combining pharma data and state of the art modeling technology to improve in Silico pKa prediction. ( 0,57982300191323 )
J. Comput. Biol. - Maximal acyclic agreement forests. ( 0,577655094208303 )
Comput Math Methods Med - Robust joint analysis with data fusion in two-stage quantitative trait genome-wide association studies. ( 0,576956177735599 )
Artif Intell Med - A token centric part-of-speech tagger for biomedical text. ( 0,574627621862684 )
Int J Comput Assist Radiol Surg - Intraoperative detection and localization of cylindrical implants in cone-beam CT image data. ( 0,572097985105275 )
Comput Methods Programs Biomed - Adaptive network based on fuzzy inference system for equilibrated urea concentration prediction. ( 0,567902489942973 )
Comput Methods Programs Biomed - Privacy-preserving Kruskal-Wallis test. ( 0,565618759634569 )
Comput. Biol. Med. - Predicting cardiac autonomic neuropathy category for diabetic data with missing values. ( 0,563632175423957 )
Comput. Biol. Med. - A straightforward approach to computer-aided polyp detection using a polyp-specific volumetric feature in CT colonography. ( 0,563365630470214 )
J. Comput. Biol. - An almost optimal algorithm for generalized threshold group testing with inhibitors. ( 0,562502543148757 )
Comput Methods Programs Biomed - Predicting body fat percentage based on gender, age and BMI by using artificial neural networks. ( 0,561359340701003 )
J. Comput. Biol. - Threshold group testing on inhibitor model. ( 0,558756227889388 )
J Clin Monit Comput - Reliable real-time calculation of heart-rate complexity in critically ill patients using multiple noisy waveform sources. ( 0,556741889934152 )
IEEE J Biomed Health Inform - Estimating energy expenditure using body-worn accelerometers: a comparison of methods, sensors number and positioning. ( 0,554403056890762 )
Comput. Biol. Med. - Fully automated computer-aided volume estimation system for thyroid planar scintigraphy. ( 0,551796695501619 )
IEEE Trans Image Process - Noise reduction of cDNA microarray images using complex wavelets. ( 0,547271689110491 )
Comput Methods Programs Biomed - Validation of subject-specific cardiovascular system models from porcine measurements. ( 0,545955417309648 )
Comput Biol Chem - A novel k-word relative measure for sequence comparison. ( 0,544310623175126 )
Med Decis Making - Predicting the ICECAP-O capability index from the WOMAC osteoarthritis index: is mapping onto capability from condition-specific health status questionnaires feasible? ( 0,543430905615794 )
Med Decis Making - Estimating health state utility values for joint health conditions: a conceptual review and critique of the current evidence. ( 0,541326674599363 )
Med Biol Eng Comput - Evaluation of multi-exponential curve fitting analysis of oxygen-quenched phosphorescence decay traces for recovering microvascular oxygen tension histograms. ( 0,540605426203594 )
Comput. Biol. Med. - Preoperative implant selection for two stage breast reconstruction with 3D imaging. ( 0,540038537766432 )
J Clin Monit Comput - Accuracy of bedside glucometry in critically ill children with peripheral hypoperfusion. ( 0,538396138488043 )
J Chem Inf Model - Metabolism site prediction based on xenobiotic structural formulas and PASS prediction algorithm. ( 0,536426344278593 )
J Chem Inf Model - Real external predictivity of QSAR models: how to evaluate it? Comparison of different validation criteria and proposal of using the concordance correlation coefficient. ( 0,536138744916445 )
J Clin Monit Comput - Measuring gas exchange with step changes in inspired oxygen: an analysis of the assumption of oxygen steady state in patients suffering from COPD. ( 0,531409865715599 )
J Clin Monit Comput - Effect of concurrent oxygen therapy on accuracy of forecasting imminent postoperative desaturation. ( 0,530958469387374 )
IEEE Trans Neural Netw Learn Syst - Application of Reinforcement Learning Algorithms for the Adaptive Computation of the Smoothing Parameter for Probabilistic Neural Network. ( 0,529741057039039 )
J Chem Inf Model - How experimental errors influence drug metabolism and pharmacokinetic QSAR/QSPR models. ( 0,526900663685542 )
Lifetime Data Anal - On collapsibility and confounding bias in Cox and Aalen regression models. ( 0,525311352539007 )
IEEE Trans Pattern Anal Mach Intell - Monotonicity and Error Type Differentiability in Performance Measures for Target Detection and Tracking in Video. ( 0,52401255173843 )
Comput Methods Programs Biomed - Ventricular activity morphological characterization: ectopic beats removal in long term atrial fibrillation recordings. ( 0,52367454535219 )
J Clin Monit Comput - Visual estimation of pulse pressure variation is not reliable: a randomized simulation study. ( 0,52262435048337 )
Med Biol Eng Comput - Wear patterns of, and wear volume formulae for, cylindrically elongated acetabular cup liners. ( 0,521514486131944 )
J Chem Inf Model - Does rational selection of training and test sets improve the outcome of QSAR modeling? ( 0,521240193644868 )
BMC Med Inform Decis Mak - The R0 package: a toolbox to estimate reproduction numbers for epidemic outbreaks. ( 0,520375390454095 )
Comput Methods Programs Biomed - Measurement error in statistical models of shape. ( 0,516075702896781 )
IEEE Trans Image Process - Sparse demixing of hyperspectral images. ( 0,515684029630748 )
J Chem Inf Model - Study of chromatographic retention of natural terpenoids by chemoinformatic tools. ( 0,515138242060992 )
Med Decis Making - Mapping QLQ-C30, HAQ, and MSIS-29 on EQ-5D. ( 0,514800019808223 )
Comput. Biol. Med. - A statistical fat-tail test of predicting regulatory regions in the Drosophila genome. ( 0,513178087548168 )
Neural Comput - Density-difference estimation. ( 0,509435654902572 )
Comput Math Methods Med - A time-varying seasonal autoregressive model-based prediction of respiratory motion for tumor following radiotherapy. ( 0,507779708868071 )
J Clin Monit Comput - Non-invasive cardiac output evaluation in postoperative cardiac surgery patients, using a new prolonged expiration-based technique. ( 0,507769227094987 )
BMC Med Inform Decis Mak - Concordance and predictive value of two adverse drug event data sets. ( 0,507316272890952 )
IEEE Trans Image Process - Efficient minimum error bounded particle resampling L1 tracker with occlusion detection. ( 0,506039237227494 )
J Clin Monit Comput - Investigation of photoplethysmographic signals and blood oxygen saturation values obtained from human splanchnic organs using a fiber optic sensor. ( 0,504576797569433 )
Brief. Bioinformatics - Data construction for phosphorylation site prediction. ( 0,503391308707437 )
Comput Methods Programs Biomed - Modelling acute renal failure using blood and breath biomarkers in rats. ( 0,502777474245377 )
J Chem Inf Model - Applicability domains for classification problems: Benchmarking of distance to models for Ames mutagenicity set. ( 0,501880410858771 )
Comput Math Methods Med - Application of genetic algorithm for discovery of core effective formulae in TCM clinical data. ( 0,501408933933271 )
Comput Math Methods Med - The failure of R0. ( 0,501322716150633 )
Int J Comput Assist Radiol Surg - A laboratory comparison of computer navigation and individualized guides for distal radius osteotomy. ( 0,500779403517687 )
J Biomed Inform - Clustering clinical trials with similar eligibility criteria features. ( 0,500251304474092 )
J Chem Inf Model - Time-split cross-validation as a method for estimating the goodness of prospective prediction. ( 0,498836734804976 )
J Chem Inf Model - GRID-based three-dimensional pharmacophores II: PharmBench, a benchmark data set for evaluating pharmacophore elucidation methods. ( 0,498103050038227 )
Neural Comput - Energy complexity of recurrent neural networks. ( 0,497150401568417 )
J Clin Monit Comput - Non-invasive measurement of cardiac output in obese children and adolescents: comparison of electrical cardiometry and transthoracic Doppler echocardiography. ( 0,496900192594907 )
Comput Methods Programs Biomed - Estimation algorithm of the bowel motility based on regression analysis of the jitter and shimmer of bowel sounds. ( 0,49450313474009 )
Comput. Biol. Med. - Missing value imputation in DNA microarrays based on conjugate gradient method. ( 0,494111252870022 )
Comput Methods Programs Biomed - Preliminary study on the accuracy of respiratory input impedance measurement using the interrupter technique. ( 0,493884994802641 )
AMIA Annu Symp Proc - Predicting the dengue incidence in Singapore using univariate time series models. ( 0,493502717099783 )
Comput Methods Programs Biomed - Effect of missing RR-interval data on nonlinear heart rate variability analysis. ( 0,493140651939442 )
Comput. Biol. Med. - Multi-Gaussian fitting for pulse waveform using Weighted Least Squares and multi-criteria decision making method. ( 0,492849551626245 )
Med Biol Eng Comput - Predicting 3D pose in partially overlapped X-ray images of knee prostheses using model-based Roentgen stereophotogrammetric analysis (RSA). ( 0,492486400475982 )
Int J Comput Assist Radiol Surg - Optimal setting of image bounding box can improve registration accuracy of diffusion tensor tractography. ( 0,492279653879555 )
Med Decis Making - Prediction of health preference values from CD4 counts in individuals with HIV. ( 0,49215331944812 )
IEEE Trans Image Process - Efficient registration of nonrigid 3-D bodies. ( 0,491646767397039 )
Neural Comput - Dynamic state and parameter estimation applied to neuromorphic systems. ( 0,490788866037099 )
Methods Inf Med - Analysis of Fluorescence Lifetime Imaging Microscopy (FLIM) data. Based on a fully automated Laguerre deconvolution method. ( 0,490508739717331 )
J. Comput. Biol. - Rich parameterization improves RNA structure prediction. ( 0,490416170323426 )
Artif Intell Med - Fuzzy model identification of dengue epidemic in Colombia based on multiresolution analysis. ( 0,490047068065352 )
Med Biol Eng Comput - Intra-protocol repeatability and inter-protocol agreement for the analysis of scapulo-humeral coordination. ( 0,488545106286674 )
BMC Med Inform Decis Mak - Optimum binary cut-off threshold of a diagnostic test: comparison of different methods using Monte Carlo technique. ( 0,488521787341145 )
J Chem Inf Model - Estimating error rates in bioactivity databases. ( 0,488390325542555 )
J Chem Inf Model - Comparative studies on some metrics for external validation of QSPR models. ( 0,488140587045355 )
Comput Methods Programs Biomed - Reducing cross terms effects in the Choi-Williams transform of mioelectric signals. ( 0,487991509428017 )
J. Med. Internet Res. - Biological calibration for web-based hearing tests: evaluation of the methods. ( 0,487341792206221 )