J Clin Monit Comput - Isocapnic hyperpnea with a portable device in Cystic Fibrosis: an agreement study between two different set-up modalities.

Tópicos

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Resumo

To evaluate the bias and precision of the respiratory muscle training device formulas to predict respiratory minute volume (RMV) and volume of the reservoir bag (BV) on a cohort of subjects with Cystic Fibrosis (CF). CF patients with available pulmonary function tests and maximal voluntary manoeuvres were included in the study. Vital capacity and maximal voluntary ventilation were extracted from subjects' records and then inserted to the manufacturer's formulas to obtain RMV and BV (measured setting). RMV and BV were compared according to standard and measured formulas in males and females. Sample was described and then processed using Bland-Altman analysis. Bland-Altman analysis for RMV revealed a bias and precision of 8.8???29?L/min in males and 28.8???16?L/min in females; 0.4???0.5?L in males and 0.7???0.4?L in females for BV. Concordance correlation coefficients for RMV were -0.03 in males and 0.02 in females; 0.22 in males and 0.03 in females for BV, reinforcing an unsatisfactory concordance between measured and manufacturer setting. This study shows considerable discrepancies between the two methods, making the degree of agreement not clinically acceptable. This might cause inappropriate setting and disservice to patients with CF.

Resumo Limpo

evalu bias precis respiratori muscl train devic formula predict respiratori minut volum rmv volum reservoir bag bv cohort subject cystic fibrosi cf cf patient avail pulmonari function test maxim voluntari manoeuvr includ studi vital capac maxim voluntari ventil extract subject record insert manufactur formula obtain rmv bv measur set rmv bv compar accord standard measur formula male femal sampl describ process use blandaltman analysi blandaltman analysi rmv reveal bias precis lmin male lmin femal l male l femal bv concord correl coeffici rmv male femal male femal bv reinforc unsatisfactori concord measur manufactur set studi show consider discrep two method make degre agreement clinic accept might caus inappropri set disservic patient cf

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