J Clin Monit Comput - Validation of the new Complior sensor to record pressure signals non-invasively.


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The Complior device (Alam Medical, France) has contributed to the rise of arterial stiffness as a measure of cardiovascular risk. In its latest version (Complior Analyse) the sensor records pressure instead of distension waveforms thus allowing the measurement of central pressure and pulse wave analysis. The aim of our study was to verify that the new sensor measures pressure waveforms accurately in both time and frequency domain. Invasive and non-invasive signals were recorded simultaneously at the radial artery and compared in the frequency and time domain in haemodynamically stable intensive care unit patients. Twelve patients entered the study (8 men, 4 women, mean age 69???17?years). Heart rate was 90???15?bpm, systolic blood pressure 133???19?mmHg and diastolic blood pressure 68???15?mmHg. There was no statistical difference in the amplitude of harmonics between the invasive signal and Complior signal. When superimposing waveforms in the time domain, there was a small difference in the form factor (4.2???2.8?%) and in the absolute area between the 2 waveforms (3.3???1.7?mmHg?s(-1)). These differences were of the same magnitude as the beat-to-beat variation of the form factor (3.3?%) and of the absolute area (3.1?mmHg?s(-1)), respectively. The second systolic peak was detectable in 4 subjects, with no statistical difference between invasive and non-invasive values. The new pressure sensor of the Complior Analyse device recorded pressure waveforms accurately and could be used to perform pressure wave analysis.

Resumo Limpo

complior devic alam medic franc contribut rise arteri stiff measur cardiovascular risk latest version complior analys sensor record pressur instead distens waveform thus allow measur central pressur puls wave analysi aim studi verifi new sensor measur pressur waveform accur time frequenc domain invas noninvas signal record simultan radial arteri compar frequenc time domain haemodynam stabl intens care unit patient twelv patient enter studi men women mean age year heart rate bpm systol blood pressur mmhg diastol blood pressur mmhg statist differ amplitud harmon invas signal complior signal superimpos waveform time domain small differ form factor absolut area waveform mmhgs differ magnitud beattobeat variat form factor absolut area mmhgs respect second systol peak detect subject statist differ invas noninvas valu new pressur sensor complior analys devic record pressur waveform accur use perform pressur wave analysi

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