J Clin Monit Comput - Composite-, plain-auditory evoked potentials index and bispectral index to measure the effects of sevoflurane.

Tópicos

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Resumo

The composite auditory evoked potentials index (cAAI) uses both cortical electroencephalogram (EEG) and response to auditory stimuli, while the bispectral index (BIS) uses only the cortical EEG and auditory evoked potentials index (AAI) uses only response to auditory stimuli. We expected that the cAAI was more useful to monitor anesthetic effect of sevoflurane than the BIS and AAI. The present study compared the changes of cAAI, AAI, and BIS in different sevoflurane concentration. Forty-five adult patients were anesthetized with sevoflurane in 50 % nitrous oxide. AAI (AEP version 1.4), cAAI (AEP version 1.6), and BIS (A-2000) were compared (each 15 patients in AAI, cAAI, and BIS groups) before induction, just before and after intubation, at 10 min since sevoflurane was set to 1.0, 1.5 and 2.0 %, and after extubation. All three indices decreased significantly before intubation. The cAAI was significantly higher than the AAI at sevoflurane 1.0 and 1.5 %. The AAI and BIS were significantly lower at sevoflurane 2.0 % than those at sevoflurane 1.0 %, but the cAAI did not. The cAAI had the largest and AAI had the smallest inter-individual variation. In sevoflurane-nitrous oxide anesthesia, cAAI was inferior to AAI and BIS to discriminate different anesthetic effect. The cAAI had larger inter-individual variation than the AAI and BIS.

Resumo Limpo

composit auditori evok potenti index caai use cortic electroencephalogram eeg respons auditori stimuli bispectr index bis use cortic eeg auditori evok potenti index aai use respons auditori stimuli expect caai use monitor anesthet effect sevofluran bis aai present studi compar chang caai aai bis differ sevofluran concentr fortyf adult patient anesthet sevofluran nitrous oxid aai aep version caai aep version bis compar patient aai caai bis group induct just intub min sinc sevofluran set extub three indic decreas signific intub caai signific higher aai sevofluran aai bis signific lower sevofluran sevofluran caai caai largest aai smallest interindividu variat sevofluranenitr oxid anesthesia caai inferior aai bis discrimin differ anesthet effect caai larger interindividu variat aai bis

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