J Clin Monit Comput - The utility of bispectral index monitoring for sedated patients treated with low-dose remifentanil.

Tópicos

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Resumo

The aim of the present study was to determine the effect of low-dose remifentanil on the monitoring quality of the Bispectral index for mechanically ventilated patients. Twelve patients who underwent elective surgery and required mechanical ventilation post-operatively were enrolled in this study with written informed consent. Eligible patients were divided into two groups. Patients in the remifentanil group received low-dose remifentanil (0.05-0.125 ?g/kg/min) and propofol (1-3 mg/kg/h). Patients in the control group received propofol (1-3 mg/kg/h). Levels of sedation were evaluated by both the Richmond Agitation Sedation Scale (RASS) and BIS monitor (A2000-XP, version 4.0, Aspect Medical Systems, Newton, USA). Monitoring quality was assessed by a correlation between RASS and BIS values. These values were assessed by single regression analysis and a P value of <0.05 was considered significant. There was a significant correlation between RASS and BIS values (P = 3 ? 10(-12), R (2) = 0.67) in the remifentanil group, but not in the control group (P = 0.50, R (2) = 0.057). The administration of low-dose remifentanil makes BIS a more precise tool for sedated patients under mechanical ventilation in the ICU.

Resumo Limpo

aim present studi determin effect lowdos remifentanil monitor qualiti bispectr index mechan ventil patient twelv patient underw elect surgeri requir mechan ventil postop enrol studi written inform consent elig patient divid two group patient remifentanil group receiv lowdos remifentanil gkgmin propofol mgkgh patient control group receiv propofol mgkgh level sedat evalu richmond agit sedat scale rass bis monitor axp version aspect medic system newton usa monitor qualiti assess correl rass bis valu valu assess singl regress analysi p valu consid signific signific correl rass bis valu p r remifentanil group control group p r administr lowdos remifentanil make bis precis tool sedat patient mechan ventil icu

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