J Clin Monit Comput - A model-based decision support system for critiquing mechanical ventilation treatments.

Tópicos

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Resumo

A computerized system for critiquing mechanical ventilation treatments is presented that can be used as an aide to the intensivist. The presented system is based on the physiological model of the subject's respiratory system. It uses modified versions of previously developed models of adult and neonatal respiratory systems to simulate the effects of different ventilator treatments on the patient's blood gases. The physiological models that have been used for research and teaching purposes by many researchers in the field include lungs, body tissue, and the brain tissue. The lung volume is continuously time-varying and the effects of shunt in the lung, changes in cardiac output and cerebral blood flow, and the arterial transport delays are included in the system. Evaluation tests were done on adult and neonate patients with different diagnoses. In both groups combined, the differences between the arterial partial pressures of CO(2) predicted by the system and the experimental values were 1.86 ? 1.6 mmHg (mean ? SD), and the differences between the predicted arterial hemoglobin oxygen saturation values, S(aO2), and the experimental values measured by using pulse oximetry, S(pO2), were 0.032 ? 0.02 (mean ? SD). The proposed system has the potential to be used alone or in combination with other decision support systems to set ventilation parameters and optimize treatment for patients on mechanical ventilation.

Resumo Limpo

computer system critiqu mechan ventil treatment present can use aid intensivist present system base physiolog model subject respiratori system use modifi version previous develop model adult neonat respiratori system simul effect differ ventil treatment patient blood gase physiolog model use research teach purpos mani research field includ lung bodi tissu brain tissu lung volum continu timevari effect shunt lung chang cardiac output cerebr blood flow arteri transport delay includ system evalu test done adult neonat patient differ diagnos group combin differ arteri partial pressur co predict system experiment valu mmhg mean sd differ predict arteri hemoglobin oxygen satur valu sao experiment valu measur use puls oximetri spo mean sd propos system potenti use alon combin decis support system set ventil paramet optim treatment patient mechan ventil

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