J Med Syst - A stationary wavelet transform based approach to registration of planning CT and setup cone beam-CT images in radiotherapy.

Tópicos

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Resumo

Image registration between planning CT images and cone beam-CT (CBCT) images is one of the key technologies of image guided radiotherapy (IGRT). Current image registration methods fall roughly into two categories: geometric features-based and image grayscale-based. Mutual information (MI) based registration, which belongs to the latter category, has been widely applied to multi-modal and mono-modal image registration. However, the standard mutual information method only focuses on the image intensity information and overlooks spatial information, leading to the instability of intensity interpolation. Due to its use of positional information, wavelet transform has been applied to image registration recently. In this study, we proposed an approach to setup CT and cone beam-CT (CBCT) image registration in radiotherapy based on the combination of mutual information (MI) and stationary wavelet transform (SWT). Firstly, SWT was applied to generate gradient images and low frequency components produced in various levels of image decomposition were eliminated. Then inverse SWT was performed on the remaining frequency components. Lastly, the rigid registration of gradient images and original images was implemented using a weighting function with the normalized mutual information (NMI) being the similarity measure, which compensates for the lack of spatial information in mutual information based image registration. Our experiment results showed that the proposed method was highly accurate and robust, and indicated a significant clinical potential in improving the accuracy of target localization in image guided radiotherapy (IGRT).

Resumo Limpo

imag registr plan ct imag cone beamct cbct imag one key technolog imag guid radiotherapi igrt current imag registr method fall rough two categori geometr featuresbas imag grayscalebas mutual inform mi base registr belong latter categori wide appli multimod monomod imag registr howev standard mutual inform method focus imag intens inform overlook spatial inform lead instabl intens interpol due use posit inform wavelet transform appli imag registr recent studi propos approach setup ct cone beamct cbct imag registr radiotherapi base combin mutual inform mi stationari wavelet transform swt first swt appli generat gradient imag low frequenc compon produc various level imag decomposit elimin invers swt perform remain frequenc compon last rigid registr gradient imag origin imag implement use weight function normal mutual inform nmi similar measur compens lack spatial inform mutual inform base imag registr experi result show propos method high accur robust indic signific clinic potenti improv accuraci target local imag guid radiotherapi igrt

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