AMIA Annu Symp Proc - Evaluation of RxNorm for Medication Clinical Decision Support.

Tópicos

{ medic(1828) order(1363) alert(1069) }
{ clinic(1479) use(1117) guidelin(835) }
{ analysi(2126) use(1163) compon(1037) }
{ concept(1167) ontolog(924) domain(897) }
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{ studi(1410) differ(1259) use(1210) }
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{ model(3480) simul(1196) paramet(876) }
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{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ age(1611) year(1155) adult(843) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ first(2504) two(1366) second(1323) }
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{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
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{ use(2086) technolog(871) perceiv(783) }
{ health(1844) social(1437) communiti(874) }
{ high(1669) rate(1365) level(1280) }
{ use(1733) differ(960) four(931) }
{ result(1111) use(1088) new(759) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

We evaluated the potential use of RxNorm to provide standardized representations of generic drug name and route of administration to facilitate management of drug lists for clinical decision support (CDS) rules. We found a clear representation of generic drug name but not route of administration. We identified several issues related to data quality, including erroneous or missing defined relationships, and the use of different concept hierarchies to represent the same drug. More importantly, we found extensive semantic precoordination of orthogonal concepts related to route and dose form, which would complicate the use of RxNorm for drug-based CDS. This study demonstrated that while RxNorm is a valuable resource for the standardization of medications used in clinical practice, additional work is required to enhance the terminology so that it can support expanded use cases, such as managing drug lists for CDS.

Resumo Limpo

evalu potenti use rxnorm provid standard represent generic drug name rout administr facilit manag drug list clinic decis support cds rule found clear represent generic drug name rout administr identifi sever issu relat data qualiti includ erron miss defin relationship use differ concept hierarchi repres drug import found extens semant precoordin orthogon concept relat rout dose form complic use rxnorm drugbas cds studi demonstr rxnorm valuabl resourc standard medic use clinic practic addit work requir enhanc terminolog can support expand use case manag drug list cds

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