J Med Syst - An image processing application for the localization and segmentation of lymphoblast cell using peripheral blood images.

Tópicos

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Resumo

An important preliminary step in the diagnosis of leukemia is the visual examination of the patient's peripheral blood smear under the microscope. Morphological changes in the white blood cells can be an indicator of the nature and severity of the disease. Manual techniques are labor intensive, slow, error prone and costly. A computerized system can be used as a supportive tool for the specialist in order to enhance and accelerate the morphological analysis process. This research present a new method that integrates color features with the morphological reconstruction to localize and isolate lymphoblast cells from a microscope image that contains many cells. The localization and segmentation are conducted using a proposed method that consists of an integration of several digital image processing techniques. 180 microscopic blood images were tested, and the proposed framework managed to obtain 100% accuracy for the localization of the lymphoblast cells and separate it from the image scene. The results obtained indicate that the proposed method can be safely used for the purpose of lymphoblast cells localization and segmentation and subsequently, aiding the diagnosis of leukemia.

Resumo Limpo

import preliminari step diagnosi leukemia visual examin patient peripher blood smear microscop morpholog chang white blood cell can indic natur sever diseas manual techniqu labor intens slow error prone cost computer system can use support tool specialist order enhanc acceler morpholog analysi process research present new method integr color featur morpholog reconstruct local isol lymphoblast cell microscop imag contain mani cell local segment conduct use propos method consist integr sever digit imag process techniqu microscop blood imag test propos framework manag obtain accuraci local lymphoblast cell separ imag scene result obtain indic propos method can safe use purpos lymphoblast cell local segment subsequ aid diagnosi leukemia

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