J Med Syst - Linkage of data from diverse data sources (LDS): a data combination model provides clinical data of corresponding specimens in biobanking information system.

Tópicos

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{ extract(1171) text(1153) clinic(932) }
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Resumo

To provide sufficient clinical data for corresponding specimens from diverse databases established before the implementation of biobanks for research purposes with respect to data privacy regulations. For this purpose, we developed a data model called "linkage of data from diverse data sources (LDS)". The data model was developed to merge clinical data from an existing local database with biospecimen repository data in our serum bank for uro-oncology. This concept combines two data models based on XML: the first stores information required to connect multiple data sources and retrieve clinical data, and the second provides a data architecture to acquire clinical and repository data. All data were anonymized and encrypted using the Advanced Encryption Standard. X.509 certificates were applied to secure data access. Furthermore, we tested the feasibility of implementing these models in the information management system for biobanking. The data concept can provide clinical and repository data of biospecimens. Only authorized receivers can access these data. Sensitive and personal data are not accessible by the data receivers. The data receiver cannot backtrack to the individual donor using the data model. The acquired data can be converted into a text file format supported by familiar statistical software. Supplementary tools were implemented to generate and view XML documents based on these data models. This data model provides an effective approach to distribute clinical and repository data from different data sources to enable data analysis compliant with data privacy regulations.

Resumo Limpo

provid suffici clinic data correspond specimen divers databas establish implement biobank research purpos respect data privaci regul purpos develop data model call linkag data divers data sourc lds data model develop merg clinic data exist local databas biospecimen repositori data serum bank urooncolog concept combin two data model base xml first store inform requir connect multipl data sourc retriev clinic data second provid data architectur acquir clinic repositori data data anonym encrypt use advanc encrypt standard x certif appli secur data access furthermor test feasibl implement model inform manag system biobank data concept can provid clinic repositori data biospecimen author receiv can access data sensit person data access data receiv data receiv backtrack individu donor use data model acquir data can convert text file format support familiar statist softwar supplementari tool implement generat view xml document base data model data model provid effect approach distribut clinic repositori data differ data sourc enabl data analysi compliant data privaci regul

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