J. Med. Internet Res. - Electronic versus paper-based assessment of health-related quality of life specific to HIV disease: reliability study of the PROQOL-HIV questionnaire.

Tópicos

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Resumo

CKGROUND: Electronic patient-reported outcomes (PRO) provide quick and usually reliable assessments of patients' health-related quality of life (HRQL).OBJECTIVE: An electronic version of the Patient-Reported Outcomes Quality of Life-human immunodeficiency virus (PROQOL-HIV) questionnaire was developed, and its face validity and reliability were assessed using standard psychometric methods.METHODS: A sample of 80 French outpatients (66% male, 52/79; mean age 46.7 years, SD 10.9) were recruited. Paper-based and electronic questionnaires were completed in a randomized crossover design (2-7 day interval). Biomedical data were collected. Questionnaire version and order effects were tested on full-scale scores in a 2-way ANOVA with patients as random effects. Test-retest reliability was evaluated using Pearson and intraclass correlation coefficients (ICC, with 95% confidence interval) for each dimension. Usability testing was carried out from patients' survey reports, specifically, general satisfaction, ease of completion, quality and clarity of user interface, and motivation to participate in follow-up PROQOL-HIV electronic assessments.RESULTS: Questionnaire version and administration order effects (N=59 complete cases) were not significant at the 5% level, and no interaction was found between these 2 factors (P=.94). Reliability indexes were acceptable, with Pearson correlations greater than .7 and ICCs ranging from .708 to .939; scores were not statistically different between the two versions. A total of 63 (79%) complete patients' survey reports were available, and 55% of patients (30/55) reported being satisfied and interested in electronic assessment of their HRQL in clinical follow-up. Individual ratings of PROQOL-HIV user interface (85%-100% of positive responses) confirmed user interface clarity and usability.CONCLUSIONS: The electronic PROQOL-HIV introduces minor modifications to the original paper-based version, following International Society for Pharmacoeconomics and Outcomes Research (ISPOR) ePRO Task Force guidelines, and shows good reliability and face validity. Patients can complete the computerized PROQOL-HIV questionnaire and the scores from the paper or electronic versions share comparable accuracy and interpretation.

Resumo Limpo

ckground electron patientreport outcom pro provid quick usual reliabl assess patient healthrel qualiti life hrqlobject electron version patientreport outcom qualiti lifehuman immunodefici virus proqolhiv questionnair develop face valid reliabl assess use standard psychometr methodsmethod sampl french outpati male mean age year sd recruit paperbas electron questionnair complet random crossov design day interv biomed data collect questionnair version order effect test fullscal score way anova patient random effect testretest reliabl evalu use pearson intraclass correl coeffici icc confid interv dimens usabl test carri patient survey report specif general satisfact eas complet qualiti clariti user interfac motiv particip followup proqolhiv electron assessmentsresult questionnair version administr order effect n complet case signific level interact found factor p reliabl index accept pearson correl greater icc rang score statist differ two version total complet patient survey report avail patient report satisfi interest electron assess hrql clinic followup individu rate proqolhiv user interfac posit respons confirm user interfac clariti usabilityconclus electron proqolhiv introduc minor modif origin paperbas version follow intern societi pharmacoeconom outcom research ispor epro task forc guidelin show good reliabl face valid patient can complet computer proqolhiv questionnair score paper electron version share compar accuraci interpret

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