J. Med. Internet Res. - Sensitivity and predictive value of 15 PubMed search strategies to answer clinical questions rated against full systematic reviews.

Tópicos

{ search(2224) databas(1162) retriev(909) }
{ decis(3086) make(1611) patient(1517) }
{ survey(1388) particip(1329) question(1065) }
{ detect(2391) sensit(1101) algorithm(908) }
{ perform(1367) use(1326) method(1137) }
{ model(2656) set(1616) predict(1553) }
{ treatment(1704) effect(941) patient(846) }
{ method(1219) similar(1157) match(930) }
{ motion(1329) object(1292) video(1091) }
{ method(984) reconstruct(947) comput(926) }
{ first(2504) two(1366) second(1323) }
{ drug(1928) target(777) effect(648) }
{ error(1145) method(1030) estim(1020) }
{ model(2341) predict(2261) use(1141) }
{ spatial(1525) area(1432) region(1030) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ patient(2837) hospit(1953) medic(668) }
{ can(774) often(719) complex(702) }
{ system(1976) rule(880) can(841) }
{ imag(2675) segment(2577) method(1081) }
{ studi(2440) review(1878) systemat(933) }
{ assess(1506) score(1403) qualiti(1306) }
{ framework(1458) process(801) describ(734) }
{ clinic(1479) use(1117) guidelin(835) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ howev(809) still(633) remain(590) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ visual(1396) interact(850) tool(830) }
{ blood(1257) pressur(1144) flow(957) }
{ medic(1828) order(1363) alert(1069) }
{ group(2977) signific(1463) compar(1072) }
{ intervent(3218) particip(2042) group(1664) }
{ method(1969) cluster(1462) data(1082) }
{ model(3404) distribut(989) bayesian(671) }
{ imag(1947) propos(1133) code(1026) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ problem(2511) optim(1539) algorithm(950) }
{ chang(1828) time(1643) increas(1301) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ algorithm(1844) comput(1787) effici(935) }
{ data(1714) softwar(1251) tool(1186) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ general(901) number(790) one(736) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ import(1318) role(1303) understand(862) }
{ compound(1573) activ(1297) structur(1058) }
{ studi(1119) effect(1106) posit(819) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ research(1218) medic(880) student(794) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ result(1111) use(1088) new(759) }
{ implement(1333) system(1263) develop(1122) }
{ estim(2440) model(1874) function(577) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ method(2212) result(1239) propos(1039) }

Resumo

CKGROUND: Clinicians perform searches in PubMed daily, but retrieving relevant studies is challenging due to the rapid expansion of medical knowledge. Little is known about the performance of search strategies when they are applied to answer specific clinical questions.OBJECTIVE: To compare the performance of 15 PubMed search strategies in retrieving relevant clinical trials on therapeutic interventions.METHODS: We used Cochrane systematic reviews to identify relevant trials for 30 clinical questions. Search terms were extracted from the abstract using a predefined procedure based on the population, interventions, comparison, outcomes (PICO) framework and combined into queries. We tested 15 search strategies that varied in their query (PIC or PICO), use of PubMed's Clinical Queries therapeutic filters (broad or narrow), search limits, and PubMed links to related articles. We assessed sensitivity (recall) and positive predictive value (precision) of each strategy on the first 2 PubMed pages (40 articles) and on the complete search output.RESULTS: The performance of the search strategies varied widely according to the clinical question. Unfiltered searches and those using the broad filter of Clinical Queries produced large outputs and retrieved few relevant articles within the first 2 pages, resulting in a median sensitivity of only 10%-25%. In contrast, all searches using the narrow filter performed significantly better, with a median sensitivity of about 50% (all P < .001 compared with unfiltered queries) and positive predictive values of 20%-30% (P < .001 compared with unfiltered queries). This benefit was consistent for most clinical questions. Searches based on related articles retrieved about a third of the relevant studies.CONCLUSIONS: The Clinical Queries narrow filter, along with well-formulated queries based on the PICO framework, provided the greatest aid in retrieving relevant clinical trials within the 2 first PubMed pages. These results can help clinicians apply effective strategies to answer their questions at the point of care.

Resumo Limpo

ckground clinician perform search pubm daili retriev relev studi challeng due rapid expans medic knowledg littl known perform search strategi appli answer specif clinic questionsobject compar perform pubm search strategi retriev relev clinic trial therapeut interventionsmethod use cochran systemat review identifi relev trial clinic question search term extract abstract use predefin procedur base popul intervent comparison outcom pico framework combin queri test search strategi vari queri pic pico use pubm clinic queri therapeut filter broad narrow search limit pubm link relat articl assess sensit recal posit predict valu precis strategi first pubm page articl complet search outputresult perform search strategi vari wide accord clinic question unfilt search use broad filter clinic queri produc larg output retriev relev articl within first page result median sensit contrast search use narrow filter perform signific better median sensit p compar unfilt queri posit predict valu p compar unfilt queri benefit consist clinic question search base relat articl retriev third relev studiesconclus clinic queri narrow filter along wellformul queri base pico framework provid greatest aid retriev relev clinic trial within first pubm page result can help clinician appli effect strategi answer question point care

Resumos Similares

Telemed J E Health - MEDLINE versus EMBASE and CINAHL for telemedicine searches. ( 0,924986782976473 )
J. Med. Internet Res. - Retrieving clinical evidence: a comparison of PubMed and Google Scholar for quick clinical searches. ( 0,911470848220507 )
BMC Med Inform Decis Mak - Glomerular disease search filters for Pubmed, Ovid Medline, and Embase: a development and validation study. ( 0,908031348635028 )
J Am Med Inform Assoc - Retrieval of diagnostic and treatment studies for clinical use through PubMed and PubMed's Clinical Queries filters. ( 0,907203056786109 )
J Am Med Inform Assoc - Search filters to identify geriatric medicine in Medline. ( 0,904583491733073 )
J Biomed Inform - On the query reformulation technique for effective MEDLINE document retrieval. ( 0,897772980226561 )
Methods Inf Med - Learning the preferences of physicians for the organization of result lists of medical evidence articles. ( 0,897383225357344 )
AMIA Annu Symp Proc - Search filter precision can be improved by NOTing out irrelevant content. ( 0,894545736636932 )
Health Info Libr J - Medical literature searches: a comparison of PubMed and Google Scholar. ( 0,894412776812686 )
J. Med. Internet Res. - Development and validation of filters for the retrieval of studies of clinical examination from Medline. ( 0,891688933883159 )
AMIA Annu Symp Proc - Evaluation of automated term groupings for detecting anaphylactic shock signals for drugs. ( 0,87198487189278 )
BMC Med Inform Decis Mak - Publication trends of shared decision making in 15 high impact medical journals: a full-text review with bibliometric analysis. ( 0,870580209684233 )
Health Info Libr J - Facilitating access to evidence: Primary Health Care Search Filter. ( 0,868568814453287 )
J Integr Bioinform - The LAILAPS search engine: a feature model for relevance ranking in life science databases. ( 0,866561442574108 )
Health Info Libr J - The performance of adverse effects search filters in MEDLINE and EMBASE. ( 0,855138332452032 )
J Am Med Inform Assoc - MEDLINE clinical queries are robust when searching in recent publishing years. ( 0,855062993275927 )
J Integr Bioinform - Classification methods for finding articles describing protein-protein interactions in PubMed. ( 0,852291280284965 )
Int J Health Geogr - HEALTH GeoJunction: place-time-concept browsing of health publications. ( 0,846849968677309 )
J Am Med Inform Assoc - Search terms and a validated brief search filter to retrieve publications on health-related values in Medline: a word frequency analysis study. ( 0,846416266764104 )
Health Info Libr J - Sensitivity and precision of adverse effects search filters in MEDLINE and EMBASE: a case study of fractures with thiazolidinediones. ( 0,843567511039008 )
Health Info Libr J - Searching for randomised controlled trials and clinical controlled trials in Thai online bibliographical biomedical databases. ( 0,820341735654005 )
Health Info Libr J - Utilisation of search filters in systematic reviews of prognosis questions. ( 0,819282901486556 )
Methods Inf Med - Developing topic-specific search filters for PubMed with click-through data. ( 0,813393466344246 )
J Biomed Inform - Reflective random indexing for semi-automatic indexing of the biomedical literature. ( 0,813180795497156 )
BMC Med Inform Decis Mak - Boolean versus ranked querying for biomedical systematic reviews. ( 0,811806014883581 )
J. Med. Internet Res. - Definition of Health 2.0 and Medicine 2.0: a systematic review. ( 0,805183550066872 )
Health Info Libr J - Assessment of indexing trends with specific and general terms for herbal medicine. ( 0,804895308370531 )
J Biomed Inform - MeSHy: Mining unanticipated PubMed information using frequencies of occurrences and concurrences of MeSH terms. ( 0,804887671310277 )
Health Info Libr J - Developing a geographic search filter to identify randomised controlled trials in Africa: finding the optimal balance between sensitivity and precision. ( 0,804448744298011 )
J Integr Bioinform - A query suggestion workflow for life science IR-systems. ( 0,803137395019743 )
J Biomed Inform - Development and evaluation of a biomedical search engine using a predicate-based vector space model. ( 0,800716277847284 )
J Integr Bioinform - The LAILAPS search engine: relevance ranking in life science databases. ( 0,800236812710779 )
BMC Med Inform Decis Mak - BOSS: context-enhanced search for biomedical objects. ( 0,795139968938611 )
J Am Med Inform Assoc - Automatically extracting sentences from Medline citations to support clinicians' information needs. ( 0,790291572749733 )
J Telemed Telecare - How to improve your PubMed/MEDLINE searches: 1. background and basic searching. ( 0,787886899467284 )
J. Med. Internet Res. - Net improvement of correct answers to therapy questions after pubmed searches: pre/post comparison. ( 0,786024552331695 )
Int J Med Inform - An analysis of clinical queries in an electronic health record search utility. ( 0,784693321476728 )
AMIA Annu Symp Proc - Does query expansion limit our learning? A comparison of social-based expansion to content-based expansion for medical queries on the internet. ( 0,781407713916715 )
Int J Med Inform - MEDRank: using graph-based concept ranking to index biomedical texts. ( 0,780271066920191 )
BMC Med Inform Decis Mak - CDAPubMed: a browser extension to retrieve EHR-based biomedical literature. ( 0,778249597717255 )
J. Med. Internet Res. - A search engine to access PubMed monolingual subsets: proof of concept and evaluation in French. ( 0,777069064250747 )
AMIA Annu Symp Proc - BIOSPIDA: A Relational Database Translator for NCBI. ( 0,777011505725155 )
J Med Syst - MIRASS: medical informatics research activity support system using information mashup network. ( 0,776923851337347 )
J Biomed Inform - Using statistical text mining to supplement the development of an ontology. ( 0,767576761514419 )
J. Med. Internet Res. - Clinician search behaviors may be influenced by search engine design. ( 0,765503919848054 )
BMC Med Inform Decis Mak - Performance evaluation of Unified Medical Language System?'s synonyms expansion to query PubMed. ( 0,765384413966115 )
J Biomed Inform - Improving search over Electronic Health Records using UMLS-based query expansion through random walks. ( 0,764805043580441 )
J Am Med Inform Assoc - Improving image retrieval effectiveness via query expansion using MeSH hierarchical structure. ( 0,764207238240934 )
Health Info Libr J - Where and how to search for information on the effectiveness of public health interventions - a case study for prevention of cardiovascular disease. ( 0,764171637948318 )
J Am Med Inform Assoc - A literature search tool for intelligent extraction of disease-associated genes. ( 0,763187423537569 )
J. Med. Internet Res. - Using Internet search engines to obtain medical information: a comparative study. ( 0,760285219520779 )
J Biomed Inform - A semi-supervised approach to extract pharmacogenomics-specific drug-gene pairs from biomedical literature for personalized medicine. ( 0,758584000029006 )
IEEE Trans Vis Comput Graph - WORDGRAPH: Keyword-in-Context Visualization for NETSPEAK's Wildcard Search. ( 0,755474240985847 )
AMIA Annu Symp Proc - Query log analysis of an electronic health record search engine. ( 0,751280883051212 )
Res Synth Methods - Comprehensive computer searches and reporting in systematic reviews. ( 0,740051190152321 )
J Chem Inf Model - Efficient substructure searching of large chemical libraries: the ABCD chemical cartridge. ( 0,737968533119679 )
J Biomed Inform - A comparison of evaluation metrics for biomedical journals, articles, and websites in terms of sensitivity to topic. ( 0,737450445786613 )
Med Decis Making - How do physicians provide statistical information about antidepressants to hypothetical patients? ( 0,736874581425669 )
Perspect Health Inf Manag - Risk factors for bladder cancer: challenges of conducting a literature search using PubMed. ( 0,736391924511291 )
AMIA Annu Symp Proc - A bottom-up approach to MEDLINE indexing recommendations. ( 0,732369043406595 )
J. Med. Internet Res. - Automatic evidence retrieval for systematic reviews. ( 0,731642916384617 )
Health Info Libr J - Can we prioritise which databases to search? A case study using a systematic review of frozen shoulder management. ( 0,730701930309895 )
Res Synth Methods - Inquisitio validus Index Medicus: A simple method of validating MEDLINE systematic review searches. ( 0,725175445931867 )
Methods Inf Med - Technology-induced errors. The current use of frameworks and models from the biomedical and life sciences literatures. ( 0,723435991473201 )
Brief. Bioinformatics - Fast and efficient searching of biological data resources--using EB-eye. ( 0,719633586488672 )
J Biomed Inform - Knowledge-based personalized search engine for the Web-based Human Musculoskeletal System Resources (HMSR) in biomechanics. ( 0,719121433579536 )
J Am Med Inform Assoc - Directing the public to evidence-based online content. ( 0,716464127495145 )
Inform Health Soc Care - Readability of online health information: implications for health literacy. ( 0,715068588692802 )
J Am Med Inform Assoc - Design and usability study of an iconic user interface to ease information retrieval of medical guidelines. ( 0,713902871012315 )
J Biomed Inform - Supporting effective health and biomedical information retrieval and navigation: a novel facet view interface evaluation. ( 0,709884094160765 )
AMIA Annu Symp Proc - Using Co-Authoring and Cross-Referencing Information for MEDLINE Indexing. ( 0,708970316009663 )
J Am Med Inform Assoc - A practical approach to achieve private medical record linkage in light of public resources. ( 0,703211864993472 )
J Am Med Inform Assoc - Clinical research data warehouse governance for distributed research networks in the USA: a systematic review of the literature. ( 0,699999693281895 )
J Integr Bioinform - GMB: an efficient query processor for biological data. ( 0,697838826992847 )
J Chem Inf Model - Speeding up chemical searches using the inverted index: the convergence of chemoinformatics and text search methods. ( 0,697103803232795 )
Methods Inf Med - A survey on visual information search behavior and requirements of radiologists. ( 0,696918088703512 )
J. Med. Internet Res. - Searching for truth: internet search patterns as a method of investigating online responses to a Russian illicit drug policy debate. ( 0,68825707085818 )
AMIA Annu Symp Proc - An automated approach for ranking journals to help in clinician decision support. ( 0,687673863417292 )
Methods Inf Med - Toward a formalization of the process to select IMIA Yearbook best papers. ( 0,686886873940354 )
J. Med. Internet Res. - The impact of search engine selection and sorting criteria on vaccination beliefs and attitudes: two experiments manipulating Google output. ( 0,685863710460523 )
AMIA Annu Symp Proc - Finding and accessing diagrams in biomedical publications. ( 0,679092626055136 )
BMC Med Inform Decis Mak - Information discovery on electronic health records using authority flow techniques. ( 0,675875289430119 )
J Biomed Inform - A mutation-centric approach to identifying pharmacogenomic relations in text. ( 0,672245004170421 )
AMIA Annu Symp Proc - Web to world: predicting transitions from self-diagnosis to the pursuit of local medical assistance in web search. ( 0,671146465283892 )
Int J Med Inform - The publication echo: effects of retrieving literature in PubMed by year of publication. ( 0,669764416316082 )
J Am Med Inform Assoc - Federated queries of clinical data repositories: the sum of the parts does not equal the whole. ( 0,664220943010545 )
Health Info Libr J - Searching MEDLINE for Aboriginal and Torres Strait Islander health literature: questionable sensitivity. ( 0,662677811934684 )
AMIA Annu Symp Proc - MeSH term explosion and author rank improve expert recommendations. ( 0,662585056003577 )
J. Med. Internet Res. - Comparative analysis of online health queries originating from personal computers and smart devices on a consumer health information portal. ( 0,662206000983197 )
Sci Data - Erratum: Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies. ( 0,66006600990165 )
J. Med. Internet Res. - Cumulative query method for influenza surveillance using search engine data. ( 0,659227418159011 )
Int J Med Inform - A study of the influence of task familiarity on user behaviors and performance with a MeSH term suggestion interface for PubMed bibliographic search. ( 0,658908374633263 )
BMC Med Inform Decis Mak - Pharmacoeconomics and its implication on priority-setting for essential medicines in Tanzania: a systematic review. ( 0,654895138618477 )
AMIA Annu Symp Proc - Optimizing the txt2MEDLINE search portal for low-resource clinical decision support. ( 0,652752682622263 )
AMIA Annu Symp Proc - Development and evaluation of a prototype search engine to meet public health information needs. ( 0,639852758562623 )
J Biomed Inform - Improving MeSH classification of biomedical articles using citation contexts. ( 0,638287930558349 )
J Biomed Inform - Small sum privacy and large sum utility in data publishing. ( 0,6378509681297 )
Med Decis Making - A pilot study using machine learning and domain knowledge to facilitate comparative effectiveness review updating. ( 0,633239972149519 )
Int J Med Inform - FindZebra: a search engine for rare diseases. ( 0,631825187094373 )
Telemed J E Health - A web search on environmental topics: what is the role of ranking? ( 0,631207561767612 )