J. Med. Internet Res. - Real-time prescription surveillance and its application to monitoring seasonal influenza activity in Japan.

Tópicos

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Resumo

CKGROUND: Real-time surveillance is fundamental for effective control of disease outbreaks, but the official sentinel surveillance in Japan collects information related to disease activity only weekly and updates it with a 1-week time lag.OBJECTIVE: To report on a prescription surveillance system using electronic records related to prescription drugs that was started in 2008 in Japan, and to evaluate the surveillance system for monitoring influenza activity during the 2009-2010 and 2010-2011 influenza seasons.METHODS: We developed an automatic surveillance system using electronic records of prescription drug purchases collected from 5275 pharmacies through the application service provider's medical claims service. We then applied the system to monitoring influenza activity during the 2009-2010 and 2010-2011 influenza seasons. The surveillance system collected information related to drugs and patients directly and automatically from the electronic prescription record system, and estimated the number of influenza cases based on the number of prescriptions of anti-influenza virus medication. Then it shared the information related to influenza activity through the Internet with the public on a daily basis.RESULTS: During the 2009-2010 influenza season, the number of influenza patients estimated by the prescription surveillance system between the 28th week of 2009 and the 12th week of 2010 was 9,234,289. In the 2010-2011 influenza season, the number of influenza patients between the 36th week of 2010 and the 12th week of 2011 was 7,153,437. The estimated number of influenza cases was highly correlated with that predicted by the official sentinel surveillance (r = .992, P < .001 for 2009-2010; r = .972, P < .001 for 2010-2011), indicating that the prescription surveillance system produced a good approximation of activity patterns.CONCLUSIONS: Our prescription surveillance system presents great potential for monitoring influenza activity and for providing early detection of infectious disease outbreaks.

Resumo Limpo

ckground realtim surveil fundament effect control diseas outbreak offici sentinel surveil japan collect inform relat diseas activ week updat week time lagobject report prescript surveil system use electron record relat prescript drug start japan evalu surveil system monitor influenza activ influenza seasonsmethod develop automat surveil system use electron record prescript drug purchas collect pharmaci applic servic provid medic claim servic appli system monitor influenza activ influenza season surveil system collect inform relat drug patient direct automat electron prescript record system estim number influenza case base number prescript antiinfluenza virus medic share inform relat influenza activ internet public daili basisresult influenza season number influenza patient estim prescript surveil system th week th week influenza season number influenza patient th week th week estim number influenza case high correl predict offici sentinel surveil r p r p indic prescript surveil system produc good approxim activ patternsconclus prescript surveil system present great potenti monitor influenza activ provid earli detect infecti diseas outbreak

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