Lifetime Data Anal - Proportional hazards regression in the presence of missing study eligibility information.

Tópicos

{ estim(2440) model(1874) function(577) }
{ first(2504) two(1366) second(1323) }
{ survey(1388) particip(1329) question(1065) }
{ algorithm(1844) comput(1787) effici(935) }
{ problem(2511) optim(1539) algorithm(950) }
{ sampl(1606) size(1419) use(1276) }
{ drug(1928) target(777) effect(648) }
{ data(3963) clinic(1234) research(1004) }
{ method(1969) cluster(1462) data(1082) }
{ perform(1367) use(1326) method(1137) }
{ group(2977) signific(1463) compar(1072) }
{ control(1307) perform(991) simul(935) }
{ method(984) reconstruct(947) comput(926) }
{ data(2317) use(1299) case(1017) }
{ activ(1138) subject(705) human(624) }
{ can(774) often(719) complex(702) }
{ learn(2355) train(1041) set(1003) }
{ studi(1410) differ(1259) use(1210) }
{ imag(1947) propos(1133) code(1026) }
{ inform(2794) health(2639) internet(1427) }
{ measur(2081) correl(1212) valu(896) }
{ studi(2440) review(1878) systemat(933) }
{ method(1557) propos(1049) approach(1037) }
{ design(1359) user(1324) use(1319) }
{ general(901) number(790) one(736) }
{ risk(3053) factor(974) diseas(938) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ age(1611) year(1155) adult(843) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ gene(2352) biolog(1181) express(1162) }
{ structur(1116) can(940) graph(676) }
{ use(1733) differ(960) four(931) }
{ model(3404) distribut(989) bayesian(671) }
{ data(1737) use(1416) pattern(1282) }
{ system(1976) rule(880) can(841) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ motion(1329) object(1292) video(1091) }
{ assess(1506) score(1403) qualiti(1306) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ extract(1171) text(1153) clinic(932) }
{ data(1714) softwar(1251) tool(1186) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ howev(809) still(633) remain(590) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ medic(1828) order(1363) alert(1069) }
{ data(3008) multipl(1320) sourc(1022) }
{ intervent(3218) particip(2042) group(1664) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ use(976) code(926) identifi(902) }
{ result(1111) use(1088) new(759) }
{ implement(1333) system(1263) develop(1122) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

We consider the study of censored survival times in the situation where the available data consist of both eligible and ineligible subjects, and information distinguishing the two groups is sometimes missing. A complete-case analysis in this context would use only subjects known to be eligible, resulting in inefficient and potentially biased estimators. We propose a two-step procedure which resembles the EM algorithm but is computationally much faster. In the first step, one estimates the conditional expectation of the missing eligibility indicators given the observed data using a logistic regression based on the complete cases (i.e., subjects with non-missing eligibility indicator). In the second step, maximum likelihood estimators are obtained from a weighted Cox proportional hazards model, with the weights being either observed eligibility indicators or estimated conditional expectations thereof. Under ignorable missingness, the estimators from the second step are proven to be consistent and asymptotically normal, with explicit variance estimators. We demonstrate through simulation that the proposed methods perform well for moderate sized samples and are robust in the presence of eligibility indicators that are missing not at random. The proposed procedure is more efficient and more robust than the complete case analysis and, unlike the EM algorithm, does not require time-consuming iteration. Although the proposed methods are applicable generally, they would be most useful for large data sets (e.g., administrative data), for which the computational savings outweigh the price one has to pay for making various approximations in avoiding iteration. We apply the proposed methods to national kidney transplant registry data.

Resumo Limpo

consid studi censor surviv time situat avail data consist elig inelig subject inform distinguish two group sometim miss completecas analysi context use subject known elig result ineffici potenti bias estim propos twostep procedur resembl em algorithm comput much faster first step one estim condit expect miss elig indic given observ data use logist regress base complet case ie subject nonmiss elig indic second step maximum likelihood estim obtain weight cox proport hazard model weight either observ elig indic estim condit expect thereof ignor missing estim second step proven consist asymptot normal explicit varianc estim demonstr simul propos method perform well moder size sampl robust presenc elig indic miss random propos procedur effici robust complet case analysi unlik em algorithm requir timeconsum iter although propos method applic general use larg data set eg administr data comput save outweigh price one pay make various approxim avoid iter appli propos method nation kidney transplant registri data

Resumos Similares

Lifetime Data Anal - A two-stage estimation in the Clayton-Oakes model with marginal linear transformation models for multivariate failure time data. ( 0,832536678804897 )
Lifetime Data Anal - Marginal semiparametric multivariate accelerated failure time model with generalized estimating equations. ( 0,802611548986819 )
Lifetime Data Anal - Computationally simple estimation and improved efficiency for special cases of double truncation. ( 0,798337502122754 )
Lifetime Data Anal - Regression analysis for cumulative incidence probability under competing risks and left-truncated sampling. ( 0,796278618606439 )
Lifetime Data Anal - A generalization of Turnbull's estimator for nonparametric estimation of the conditional survival function with interval-censored data. ( 0,791354855124205 )
Lifetime Data Anal - Estimation of treatment effects based on possibly misspecified Cox regression. ( 0,787689522671756 )
Med Decis Making - Generalized additive models for the analysis of EQ-5D utility data. ( 0,784053708121772 )
Res Synth Methods - Robust variance estimation in meta-regression with dependent effect size estimates. ( 0,782904090357457 )
Neural Comput - Reliability of information-based integration of EEG and fMRI data: a simulation study. ( 0,782343646789398 )
Med Decis Making - Eliciting benefit-risk preferences and probability-weighted utility using choice-format conjoint analysis. ( 0,779884309484842 )
Lifetime Data Anal - Predictive comparison of joint longitudinal-survival modeling: a case study illustrating competing approaches. ( 0,779584313386149 )
Lifetime Data Anal - Nonparametric quasi-likelihood for right censored data. ( 0,776558207895733 )
Med Decis Making - Regression estimators for generic health-related quality of life and quality-adjusted life years. ( 0,775741619318652 )
Lifetime Data Anal - Likelihood ratio procedures and tests of fit in parametric and semiparametric copula models with censored data. ( 0,774558948439453 )
Lifetime Data Anal - Profile local linear estimation of generalized semiparametric regression model for longitudinal data. ( 0,771165447389996 )
Lifetime Data Anal - Regression analysis based on conditional likelihood approach under semi-competing risks data. ( 0,770185639024159 )
Lifetime Data Anal - Local linear estimation of concordance probability with application to covariate effects models on association for bivariate failure-time data. ( 0,768567490491 )
Lifetime Data Anal - Estimation in a competing risks proportional hazards model under length-biased sampling with censoring. ( 0,768133524904046 )
Lifetime Data Anal - Nonparametric estimation of the cumulative intensities in an interval censored competing risks model. ( 0,768131044058367 )
Lifetime Data Anal - A pool-adjacent-violators type algorithm for non-parametric estimation of current status data with dependent censoring. ( 0,762350522352846 )
Med Decis Making - Underestimation of uncertainties in health utilities derived from mapping algorithms involving health-related quality-of-life measures: statistical explanations and potential remedies. ( 0,76146227508463 )
Lifetime Data Anal - Non-crossing weighted kernel quantile regression with right censored data. ( 0,761164068317798 )
Lifetime Data Anal - Semiparametric additive marginal regression models for multiple type recurrent events. ( 0,757759761621919 )
Lifetime Data Anal - Estimating treatment effects on the marginal recurrent event mean in the presence of a terminating event. ( 0,756184238792025 )
Lifetime Data Anal - Survival estimation through the cumulative hazard function with monotone natural cubic splines. ( 0,751893178098363 )
Lifetime Data Anal - Pseudo-observations for competing risks with covariate dependent censoring. ( 0,751562361252677 )
Comput Methods Programs Biomed - Poisson regression models outperform the geometrical model in estimating the peak-to-trough ratio of seasonal variation: a simulation study. ( 0,747297721409636 )
Lifetime Data Anal - The beta modified Weibull distribution. ( 0,746574334247395 )
Res Synth Methods - Comparison of statistical inferences from the DerSimonian-Laird and alternative random-effects model meta-analyses - an empirical assessment of 920 Cochrane primary outcome meta-analyses. ( 0,746424934468703 )
Lifetime Data Anal - Events per variable for risk differences and relative risks using pseudo-observations. ( 0,746032178214358 )
Med Decis Making - Calculating Utility Decrements Associated With an Adverse Event: Marginal Tobit and CLAD Coefficients Should Be Used With Caution. ( 0,738921016491212 )
Lifetime Data Anal - Nonparametric estimation of current status data with dependent censoring. ( 0,736395266080447 )
Comput Methods Programs Biomed - Flexible multivariate marginal models for analyzing multivariate longitudinal data, with applications in R. ( 0,735410344039888 )
Lifetime Data Anal - Linear regression analysis of survival data with missing censoring indicators. ( 0,733333920714961 )
Lifetime Data Anal - Imputation for semiparametric transformation models with biased-sampling data. ( 0,73251418195177 )
Lifetime Data Anal - Cox regression for mixed case interval-censored data with covariate errors. ( 0,730750907631397 )
Lifetime Data Anal - Simultaneous marginal survival estimators when doubly censored data is present. ( 0,728266057093364 )
Res Synth Methods - Semiparametric hazard function estimation in meta-analysis for time to event data. ( 0,728081723609844 )
Lifetime Data Anal - Semiparametric methods for center effect measures based on the ratio of survival functions. ( 0,725751755859758 )
J. Comput. Biol. - An optimization-based sampling scheme for phylogenetic trees. ( 0,723674296863526 )
Comput Methods Programs Biomed - mmm: an R package for analyzing multivariate longitudinal data with multivariate marginal models. ( 0,723655656223574 )
IEEE Trans Image Process - The sparse matrix transform for covariance estimation and analysis of high dimensional signals. ( 0,723477690823924 )
Res Synth Methods - Combining study outcome measures using dominance adjusted weights. ( 0,722463217054744 )
Res Synth Methods - Multivariate fixed- and random-effects models for summarizing ordinal data in meta-analysis of diagnostic staging studies. ( 0,722387005624984 )
Comput Methods Programs Biomed - A simulation procedure based on copulas to generate clustered multi-state survival data. ( 0,722368153258432 )
IEEE Trans Pattern Anal Mach Intell - Learning Graphical Model Parameters with Approximate Marginal Inference. ( 0,716802601940907 )
Neural Comput - Firing variability is higher than deduced from the empirical coefficient of variation. ( 0,716784592999179 )
Med Decis Making - Adjusting survival time estimates to account for treatment switching in randomized controlled trials--an economic evaluation context: methods, limitations, and recommendations. ( 0,716667712477548 )
Lifetime Data Anal - A hierarchical frailty model applied to two-generation melanoma data. ( 0,713512710796813 )
Lifetime Data Anal - On estimation of linear transformation models with nested case-control sampling. ( 0,713005280850743 )
Comput Math Methods Med - Application of seemingly unrelated regression in medical data with intermittently observed time-dependent covariates. ( 0,712523651767379 )
Res Synth Methods - Linear inference for mixed treatment comparison meta-analysis: A two-stage approach. ( 0,711120591136359 )
Lifetime Data Anal - Evaluating hospital readmission rates in dialysis facilities; adjusting for hospital effects. ( 0,71064438366962 )
IEEE Trans Pattern Anal Mach Intell - Maximum Likelihood Estimation of Depth Maps Using Photometric Stereo. ( 0,70977694346886 )
IEEE Trans Pattern Anal Mach Intell - Covariate Shift Adaptation for Discriminative 3D Pose Estimation. ( 0,709470158247123 )
Comput Math Methods Med - Gray's time-varying coefficients model for posttransplant survival of pediatric liver transplant recipients with a diagnosis of cancer. ( 0,706932838956283 )
Neural Comput - ParceLiNGAM: a causal ordering method robust against latent confounders. ( 0,70229610466553 )
Res Synth Methods - Meta-analysis of time-to-event data: a comparison of two-stage methods. ( 0,699797612385471 )
Med Biol Eng Comput - Clinical applications of musculoskeletal modelling for the shoulder and upper limb. ( 0,698340905967775 )
Lifetime Data Anal - Estimation of cumulative incidence functions when the lifetime distributions are uniformly stochastically ordered. ( 0,698133098012721 )
Lifetime Data Anal - Robust inference in discrete hazard models for randomized clinical trials. ( 0,697618656526405 )
IEEE Trans Image Process - A tuned mesh-generation strategy for image representation based on data-dependent triangulation. ( 0,692196051769287 )
Lifetime Data Anal - Additive-multiplicative rates model for recurrent events. ( 0,692160509475379 )
J Chem Inf Model - Estimation of environment-related properties of chemicals for design of sustainable processes: development of group-contribution+ (GC+) property models and uncertainty analysis. ( 0,689680231040592 )
Lifetime Data Anal - Statistical inference based on the nonparametric maximum likelihood estimator under double-truncation. ( 0,685891175882499 )
Lifetime Data Anal - Parameter inference from hitting times for perturbed Brownian motion. ( 0,685133389344024 )
Neural Comput - An estimation of generalized bradley-terry models based on the em algorithm. ( 0,684727110075969 )
Comput Methods Programs Biomed - Bayesian Decision Trees for predicting survival of patients: a study on the US National Trauma Data Bank. ( 0,684385741055476 )
Lifetime Data Anal - Quantifying the average of the time-varying hazard ratio via a class of transformations. ( 0,67637467533561 )
Lifetime Data Anal - Marginal hazard regression for correlated failure time data with auxiliary covariates. ( 0,67567194284986 )
Lifetime Data Anal - Comparison of stopped Cox regression with direct methods such as pseudo-values and binomial regression. ( 0,675441365988117 )
Lifetime Data Anal - Regression analysis of informative current status data with the additive hazards model. ( 0,671779905957063 )
Lifetime Data Anal - Nonparametric estimation with recurrent competing risks data. ( 0,670446387736011 )
Med Biol Eng Comput - Non-invasive continuous glucose monitoring: improved accuracy of point and trend estimates of the Multisensor system. ( 0,669913182234409 )
Neural Comput - On quadrature methods for refractory point process likelihoods. ( 0,668877707850771 )
Comput Methods Programs Biomed - Model based period analysis of absolute and relative survival with R: data preparation, model fitting and derivation of survival estimates. ( 0,668619513001977 )
Brief. Bioinformatics - On the validity of time-dependent AUC estimators. ( 0,668313919393046 )
Lifetime Data Anal - Confidence bands for the difference between two median survival times as a function of covariates. ( 0,666885132955201 )
Lifetime Data Anal - Robust methods to improve efficiency and reduce bias in estimating survival curves in randomized clinical trials. ( 0,66634166307666 )
Lifetime Data Anal - Semiparametric estimation of treatment effect with time-lagged response in the presence of informative censoring. ( 0,666204771215666 )
Neural Comput - Some sampling properties of common phase estimators. ( 0,664756724910517 )
Res Synth Methods - Robust variance estimation with dependent effect sizes: practical considerations including a software tutorial in Stata and spss. ( 0,663038521815382 )
Neural Comput - A Monte Carlo Metropolis-Hastings algorithm for sampling from distributions with intractable normalizing constants. ( 0,662231023271601 )
Lifetime Data Anal - A parametric model fitting time to first event for overdispersed data: application to time to relapse in multiple sclerosis. ( 0,661287895378035 )
Lifetime Data Anal - Matched survival data in a co-twin control design. ( 0,660100606993412 )
Lifetime Data Anal - Censored quantile regression for residual lifetimes. ( 0,659926209710194 )
Comput Math Methods Med - Application of multivariate modeling for radiation injury assessment: a proof of concept. ( 0,659532597397699 )
Lifetime Data Anal - Comparison of estimators in nested case-control studies with multiple outcomes. ( 0,659378667613571 )
Comput Methods Programs Biomed - A warning concerning the estimation of multinomial logistic models with correlated responses in SAS. ( 0,65933071377665 )
IEEE Trans Image Process - Nonlinearity detection in hyperspectral images using a polynomial post-nonlinear mixing model. ( 0,657213216646272 )
Lifetime Data Anal - An introduction to survival models: in honor of Ross Prentice. ( 0,656762085599231 )
Neural Comput - Least squares estimation without priors or supervision. ( 0,65645077242259 )
Lifetime Data Anal - Proportional hazards regression with interval censored data using an inverse probability weight. ( 0,6557384331267 )
Neural Comput - Nonparametric estimation of K?llback-Leibler divergence. ( 0,654248118505958 )
Lifetime Data Anal - Estimation of odds of concordance based on the Aalen additive model. ( 0,652285165125894 )
Lifetime Data Anal - Competing risks with missing covariates: effect of haplotypematch on hematopoietic cell transplant patients. ( 0,650046503880786 )
Lifetime Data Anal - A functional inference for multivariate current status data with mismeasured covariate. ( 0,649773998561978 )
Lifetime Data Anal - Empirical receiver operating characteristic curve for two-sample comparison with cure fractions. ( 0,647778877283918 )
J Chem Inf Model - Jackknife-based selection of Gram-Schmidt orthogonalized descriptors in QSAR. ( 0,647511125019607 )
Neural Comput - A framework for evaluating pairwise and multiway synchrony among stimulus-driven neurons. ( 0,644051052386969 )