Med Biol Eng Comput - Theoretical development and critical analysis of burst frequency equations for passive valves on centrifugal microfluidic platforms.

Tópicos

{ signal(2180) analysi(812) frequenc(800) }
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{ framework(1458) process(801) describ(734) }
{ data(1714) softwar(1251) tool(1186) }
{ data(3963) clinic(1234) research(1004) }
{ model(2341) predict(2261) use(1141) }
{ blood(1257) pressur(1144) flow(957) }
{ estim(2440) model(1874) function(577) }
{ process(1125) use(805) approach(778) }
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Resumo

This paper presents a theoretical development and critical analysis of the burst frequency equations for capillary valves on a microfluidic compact disc (CD) platform. This analysis includes background on passive capillary valves and the governing models/equations that have been developed to date. The implicit assumptions and limitations of these models are discussed. The fluid meniscus dynamics before bursting is broken up into a multi-stage model and a more accurate version of the burst frequency equation for the capillary valves is proposed. The modified equations are used to evaluate the effects of various CD design parameters such as the hydraulic diameter, the height to width aspect ratio, and the opening wedge angle of the channel on the burst pressure.

Resumo Limpo

paper present theoret develop critic analysi burst frequenc equat capillari valv microfluid compact disc cd platform analysi includ background passiv capillari valv govern modelsequ develop date implicit assumpt limit model discuss fluid meniscus dynam burst broken multistag model accur version burst frequenc equat capillari valv propos modifi equat use evalu effect various cd design paramet hydraul diamet height width aspect ratio open wedg angl channel burst pressur

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