Med Biol Eng Comput - A coupled flow-acoustic computational study of bruits from a modeled stenosed artery.

Tópicos

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Resumo

The sound generated by blood flow in stenosed arteries is investigated for a model that consists of a channel with a one-sided constriction. The blood flow-induced arterial "bruits" are computed directly using a hybrid approach wherein the hemodynamic flow field is solved by an immersed boundary, incompressible flow solver, and the sound generation is modeled by a first-principles approach that employs the linearized compressible perturbation equations. The transmission and propagation of the sound through the surrounding biological tissues is also modeled with a simplified, linear structural wave equation. The flow field inside the artery and the bruit sound signal at the epidermal surface are examined to delineate the precise source of the arterial bruit and the correlation between the bruit and the arterial wall pressure fluctuations. It is found that the bruits are related primarily to the time-derivative of the integrated pressure force on the post-stenotic segment of arterial wall. The current study provides a clear perspective on the generation of bruits from stenosed arteries and enables an assessment of the conjectures of previous researchers regarding the source of arterial bruits.

Resumo Limpo

sound generat blood flow stenos arteri investig model consist channel onesid constrict blood flowinduc arteri bruit comput direct use hybrid approach wherein hemodynam flow field solv immers boundari incompress flow solver sound generat model firstprincipl approach employ linear compress perturb equat transmiss propag sound surround biolog tissu also model simplifi linear structur wave equat flow field insid arteri bruit sound signal epiderm surfac examin delin precis sourc arteri bruit correl bruit arteri wall pressur fluctuat found bruit relat primarili timederiv integr pressur forc poststenot segment arteri wall current studi provid clear perspect generat bruit stenos arteri enabl assess conjectur previous research regard sourc arteri bruit

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