Med Biol Eng Comput - Synthesis of optimal electrical stimulation patterns for functional motion restoration: applied to spinal cord-injured patients.

Tópicos

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Resumo

We investigated the synthesis of electrical stimulation patterns for functional movement restoration in human paralyzed limbs. We considered the knee joint system, co-activated by the stimulated quadriceps and hamstring muscles. This synthesis is based on optimized functional electrical stimulation (FES) patterns to minimize muscular energy consumption and movement efficiency criteria. This two-part work includes a multi-scale physiological muscle model, based on Huxley's formulation. In the simulation, three synthesis strategies were investigated and compared in terms of muscular energy consumption and co-contraction levels. In the experimental validation, the synthesized FES patterns were carried out on the quadriceps-knee joint system of four complete spinal cord injured subjects. Surface stimulation was applied to all subjects, except for one FES-implanted subject who received neural stimulation. In each experimental validation, the model was adapted to the subject through a parameter identification procedure. Simulation results were successful and showed high co-contraction levels when reference trajectories were tracked. Experimental validation results were encouraging, as the desired and measured trajectories showed good agreement, with an 8.4 % rms error in a subject without substantial time-varying behavior. We updated the maximal isometric force in the model to account for time-varying behavior, which improved the average rms errors from 31.4 to 13.9 % for all subjects.

Resumo Limpo

investig synthesi electr stimul pattern function movement restor human paralyz limb consid knee joint system coactiv stimul quadricep hamstr muscl synthesi base optim function electr stimul fes pattern minim muscular energi consumpt movement effici criteria twopart work includ multiscal physiolog muscl model base huxley formul simul three synthesi strategi investig compar term muscular energi consumpt cocontract level experiment valid synthes fes pattern carri quadricepskne joint system four complet spinal cord injur subject surfac stimul appli subject except one fesimpl subject receiv neural stimul experiment valid model adapt subject paramet identif procedur simul result success show high cocontract level refer trajectori track experiment valid result encourag desir measur trajectori show good agreement rms error subject without substanti timevari behavior updat maxim isometr forc model account timevari behavior improv averag rms error subject

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