Med Biol Eng Comput - Modeling the pharyngeal anatomical effects on breathing resistance and aerodynamically generated sound.

Tópicos

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Resumo

The objective of this study was to systematically assess the effects of pharyngeal anatomical details on breathing resistance and acoustic characteristics by means of computational modeling. A physiologically realistic nose-throat airway was reconstructed from medical images. Individual airway anatomy such as the uvula, pharynx, and larynx was then isolated for examination by gradually simplifying this image-based model geometry. Large eddy simulations with the FW-H acoustics model were used to simulate airflows and acoustic sound generation with constant flow inhalations in rigid-walled airway geometries. Results showed that pharyngeal anatomical details exerted a significant impact on breathing resistance and energy distribution of acoustic sound. The uvula constriction induced considerably increased levels of pressure drop and acoustic power in the pharynx, which could start and worsen snoring symptoms. Each source anatomy was observed to generate a unique spectrum with signature peak frequencies and energy distribution. Moreover, severe pharyngeal airway narrowing led to an upward shift of sound energy in the high-frequency range. Results indicated that computational aeroacoustic modeling appeared to be a practical tool to study breathing-related disorders. Specifically, high-frequency acoustic signals might disclose additional clues to the mechanism of apneic snoring and should be included in future acoustic studies.

Resumo Limpo

object studi systemat assess effect pharyng anatom detail breath resist acoust characterist mean comput model physiolog realist nosethroat airway reconstruct medic imag individu airway anatomi uvula pharynx larynx isol examin gradual simplifi imagebas model geometri larg eddi simul fwh acoust model use simul airflow acoust sound generat constant flow inhal rigidwal airway geometri result show pharyng anatom detail exert signific impact breath resist energi distribut acoust sound uvula constrict induc consider increas level pressur drop acoust power pharynx start worsen snore symptom sourc anatomi observ generat uniqu spectrum signatur peak frequenc energi distribut moreov sever pharyng airway narrow led upward shift sound energi highfrequ rang result indic comput aeroacoust model appear practic tool studi breathingrel disord specif highfrequ acoust signal might disclos addit clue mechan apneic snore includ futur acoust studi

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