Med Biol Eng Comput - Patient-specific computational fluid dynamics: structured mesh generation from coronary angiography.

Tópicos

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{ model(2341) predict(2261) use(1141) }
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{ state(1844) use(1261) util(961) }
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Resumo

Patient-specific simulations are widely used to investigate the local hemodynamics within realistic morphologies. However, pre-processing and mesh generation are time consuming, operator dependent, and the quality of the resulting mesh is often suboptimal. Therefore, a semi-automatic methodology for patient-specific reconstruction and structured meshing of a left coronary tree from biplane angiography is presented. Seven hexahedral grids have been generated with the new method (50,000-3,200,000 cells) and compared to nine unstructured tetrahedral grids with prismatic boundary layer (150,000-3,100,000 cells). Steady-state blood flow simulation using Computational Fluid Dynamics (CFD) has been used to calculate the Wall Shear Stress (WSS). Our results (99 percentile, area-weighted and local WSS values along a line) demonstrate that hexahedral meshes with respect to tetrahedral/prismatic meshes converge better, and for the same accuracy of the result, six times less cells and 14 times less computational time are required. Hexahedral meshes are superior to tetrahedral/prismatic meshes and should be preferred for the calculation of the WSS.

Resumo Limpo

patientspecif simul wide use investig local hemodynam within realist morpholog howev preprocess mesh generat time consum oper depend qualiti result mesh often suboptim therefor semiautomat methodolog patientspecif reconstruct structur mesh left coronari tree biplan angiographi present seven hexahedr grid generat new method cell compar nine unstructur tetrahedr grid prismat boundari layer cell steadyst blood flow simul use comput fluid dynam cfd use calcul wall shear stress wss result percentil areaweight local wss valu along line demonstr hexahedr mesh respect tetrahedralprismat mesh converg better accuraci result six time less cell time less comput time requir hexahedr mesh superior tetrahedralprismat mesh prefer calcul wss

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