Med Biol Eng Comput - Quantitative differences in intervertebral disc-matrix composition with age-related degeneration.

Tópicos

{ age(1611) year(1155) adult(843) }
{ sequenc(1873) structur(1644) protein(1328) }
{ extract(1171) text(1153) clinic(932) }
{ sampl(1606) size(1419) use(1276) }
{ high(1669) rate(1365) level(1280) }
{ inform(2794) health(2639) internet(1427) }
{ chang(1828) time(1643) increas(1301) }
{ cancer(2502) breast(956) screen(824) }
{ method(1219) similar(1157) match(930) }
{ featur(3375) classif(2383) classifi(1994) }
{ model(2220) cell(1177) simul(1124) }
{ search(2224) databas(1162) retriev(909) }
{ model(2656) set(1616) predict(1553) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ structur(1116) can(940) graph(676) }
{ implement(1333) system(1263) develop(1122) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ model(3404) distribut(989) bayesian(671) }
{ can(774) often(719) complex(702) }
{ imag(1947) propos(1133) code(1026) }
{ data(1737) use(1416) pattern(1282) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ studi(2440) review(1878) systemat(933) }
{ motion(1329) object(1292) video(1091) }
{ assess(1506) score(1403) qualiti(1306) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ method(1557) propos(1049) approach(1037) }
{ data(1714) softwar(1251) tool(1186) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ care(1570) inform(1187) nurs(1089) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ howev(809) still(633) remain(590) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ data(2317) use(1299) case(1017) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ first(2504) two(1366) second(1323) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

This study was carried out to determine the effect of age on the intervertebral disc, using a rabbit model. Anulus fibrosus and nucleus pulposus tissue from New Zealand white rabbits aged 3 years old (old rabbits) and 6 months old (young rabbits) were used. The water content, the proteoglycan, the DNA content, and the mRNA levels of aggrecan, type I collagen, and type II collagen were all measured for each sample. Water, proteoglycan, DNA, and the mRNA levels of aggrecan and type II collagen were all greater in the nucleus pulposus of the young rabbits as compared to the old. For the anulus fibrosus, the difference between young and old is less marked with only proteoglycan and DNA being greater in the young disc as compared to the old. Clearly, according to our results, it is the nucleus pulposus that suffers the brunt of the changes with age.

Resumo Limpo

studi carri determin effect age intervertebr disc use rabbit model anulus fibrosus nucleus pulposus tissu new zealand white rabbit age year old old rabbit month old young rabbit use water content proteoglycan dna content mrna level aggrecan type collagen type ii collagen measur sampl water proteoglycan dna mrna level aggrecan type ii collagen greater nucleus pulposus young rabbit compar old anulus fibrosus differ young old less mark proteoglycan dna greater young disc compar old clear accord result nucleus pulposus suffer brunt chang age

Resumos Similares

J. Med. Internet Res. - Computer skills and internet use in adults aged 50-74 years: influence of hearing difficulties. ( 0,770799440868848 )
J. Med. Internet Res. - Online health-searching behavior among HIV-seropositive and HIV-seronegative men who have sex with men in the Baltimore and Washington, DC area. ( 0,710471382882001 )
Int J Health Geogr - A case-referent study: light at night and breast cancer risk in Georgia. ( 0,707608862481533 )
Int J Health Geogr - Association of duration of residence in the southeastern United States with chronic kidney disease may differ by race: the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort study. ( 0,697182812885522 )
Comput. Biol. Med. - A preliminary study on the differences in male and female muscle force distribution patterns during squatting and lunging maneuvers. ( 0,696027868908054 )
Med Decis Making - Thinking about numbers is not my idea of fun: need for cognition mediates age differences in numeracy performance. ( 0,695955444141685 )
Health Informatics J - Factors influencing Internet usage in older adults (65 years and above) living in rural and urban Sweden. ( 0,694592737628356 )
J. Med. Internet Res. - The digital divide among low-income homebound older adults: Internet use patterns, eHealth literacy, and attitudes toward computer/Internet use. ( 0,679159638980693 )
Comput Math Methods Med - Use of CHAID decision trees to formulate pathways for the early detection of metabolic syndrome in young adults. ( 0,676069735262215 )
J Am Med Inform Assoc - Social disparities in internet patient portal use in diabetes: evidence that the digital divide extends beyond access. ( 0,670238206981147 )
Med Decis Making - Subjective numeracy and preference to stay with the status quo. ( 0,664799282195557 )
Telemed J E Health - Men calling healthline. ( 0,65849542301153 )
J. Med. Internet Res. - Internet based computer tailored feedback on sunscreen use. ( 0,650233534223724 )
Int J Health Geogr - Changing patterns in the association between regional socio-economic context and dental caries experience according to gender and age: a multilevel study in Korean adults. ( 0,647643980750555 )
J. Med. Internet Res. - Subdividing the digital divide: differences in internet access and use among rural residents with medical limitations. ( 0,639452931498926 )
J. Med. Internet Res. - Internet use among older adults: association with health needs, psychological capital, and social capital. ( 0,637846618520953 )
Med Decis Making - Health-Related Quality of Life in HIV-Infected and At-Risk Women: The Impact of Illicit Drug Use and Hepatitis C on a Community Preference Weighted Measure. ( 0,63566441864223 )
Int J Comput Assist Radiol Surg - Use of normative distribution of gray to white matter ratio in orthogonal planes in human brain studies and computer-assisted neuroradiology. ( 0,63387804107327 )
Telemed J E Health - A U.K. case study of who uses NHS direct: investigating the impact of age, gender, and deprivation on the utilization of NHS direct. ( 0,633744859108101 )
Int J Health Geogr - Neighborhood level risk factors for type 1 diabetes in youth: the SEARCH case-control study. ( 0,6309185782866 )
J. Med. Internet Res. - How an online intervention to prevent excessive gestational weight gain is used and by whom: a randomized controlled process evaluation. ( 0,630774797233546 )
J. Med. Internet Res. - Keywords to recruit Spanish- and English-speaking participants: evidence from an online postpartum depression randomized controlled trial. ( 0,628932623506382 )
J. Med. Internet Res. - Association of eHealth literacy with colorectal cancer knowledge and screening practice among internet users in Japan. ( 0,621958336139285 )
Comput. Biol. Med. - Neural network analysis of employment history as a risk factor for prostate cancer. ( 0,62127463031519 )
Telemed J E Health - E-health use in african american internet users: can new tools address old disparities? ( 0,608456287065068 )
J. Med. Internet Res. - Internet access and use in adults with hearing loss. ( 0,6076951593361 )
Int J Health Geogr - Spatial epidemiology of dry eye disease: findings from South Korea. ( 0,605405868340724 )
J. Med. Internet Res. - Relationship between health service use and health information technology use among older adults: analysis of the US National Health Interview Survey. ( 0,604890858014506 )
Comput. Biol. Med. - Indicators of hypertriglyceridemia from anthropometric measures based on data mining. ( 0,604362676248919 )
J. Med. Internet Res. - Recruitment via the Internet and social networking sites: the 1989-1995 cohort of the Australian Longitudinal Study on Women's Health. ( 0,60289756597292 )
Spat Spatiotemporal Epidemiol - Imputational modeling of spatial context and social environmental predictors of walking in an underserved community: the PATH trial. ( 0,602454679138262 )
J. Med. Internet Res. - Online schools and children with special health and educational needs: comparison with performance in traditional schools. ( 0,60232449109379 )
Comput. Biol. Med. - Prediction of metabolic syndrome using artificial neural network system based on clinical data including insulin resistance index and serum adiponectin. ( 0,600869984263625 )
Spat Spatiotemporal Epidemiol - The association between the density of retail tobacco outlets, individual smoking status, neighbourhood socioeconomic status and school locations in New South Wales, Australia. ( 0,600645683117385 )
J. Med. Internet Res. - Determinants of follow-up participation in the Internet-based European influenza surveillance platform Influenzanet. ( 0,600039761397424 )
J. Med. Internet Res. - Personal health record reach in the Veterans Health Administration: a cross-sectional analysis. ( 0,598546864520835 )
Int J Health Geogr - Characteristics of residential areas and transportational walking among frail and non-frail Dutch elderly: does the size of the area matter? ( 0,598460041428274 )
J. Med. Internet Res. - Patient ability and willingness to participate in a web-based intervention to improve hypertension control. ( 0,597273164510936 )
J. Med. Internet Res. - Young men's views toward the barriers and facilitators of Internet-based Chlamydia trachomatis screening: qualitative study. ( 0,595368532561498 )
J. Med. Internet Res. - Trust in the internet as a health resource among older adults: analysis of data from a nationally representative survey. ( 0,595136604896071 )
Med Decis Making - Numbers matter to informed patient choices: a randomized design across age and numeracy levels. ( 0,588088818533888 )
Med Biol Eng Comput - Quantitative geometric analysis of rib, costal cartilage and sternum from childhood to teenagehood. ( 0,587565850063172 )
J. Med. Internet Res. - Who participates in Web-assisted tobacco interventions? The QUIT-PRIMO and National Dental Practice-Based Research Network Hi-Quit studies. ( 0,587422389133148 )
J Clin Monit Comput - Influence of age and gender on autonomic regulation of heart. ( 0,587374380783999 )
Comput Math Methods Med - Association of perceived stress with stressful life events, lifestyle and sociodemographic factors: a large-scale community-based study using logistic quantile regression. ( 0,586731453355885 )
J Innov Health Inform - Characteristics of electronic patient-provider messaging system utilisation in an urban health care organisation. ( 0,585651607082273 )
Methods Inf Med - Statistical process control for monitoring standardized mortality ratios of a classification tree model. ( 0,584989687139804 )
J. Med. Internet Res. - Using the Internet to help with diet, weight, and physical activity: results from the Health Information National Trends Survey (HINTS). ( 0,584166768366942 )
Inform Health Soc Care - Pregnant women's use of the internet in relation to their pregnancy in Izmir, Turkey. ( 0,583607414079315 )
Int J Health Geogr - People living in hilly residential areas in metropolitan Perth have less diabetes: spurious association or important environmental determinant? ( 0,582130200987534 )
Int J Health Geogr - The proportion of youths' physical inactivity attributable to neighbourhood built environment features. ( 0,578313285143625 )
Med Biol Eng Comput - Age estimation using cortical surface pattern combining thickness with curvatures. ( 0,575835525076206 )
BMC Med Inform Decis Mak - Detecting referral and selection bias by the anonymous linkage of practice, hospital and clinic data using Secure and Private Record Linkage (SAPREL): case study from the evaluation of the Improved Access to Psychological Therapy (IAPT) service. ( 0,571374976866292 )
Int J Health Geogr - Spatial association of racial/ethnic disparities between late-stage diagnosis and mortality for female breast cancer: where to intervene? ( 0,570996009662605 )
J. Med. Internet Res. - Predictors of eHealth usage: insights on the digital divide from the Health Information National Trends Survey 2012. ( 0,570685381702285 )
J. Med. Internet Res. - Who uses physician-rating websites? Differences in sociodemographic variables, psychographic variables, and health status of users and nonusers of physician-rating websites. ( 0,568276327148381 )
BMC Med Inform Decis Mak - Combinational risk factors of metabolic syndrome identified by fuzzy neural network analysis of health-check data. ( 0,567794428059014 )
J. Med. Internet Res. - Impact of the presence of medical equipment in images on viewers' perceptions of the trustworthiness of an individual on-screen. ( 0,564121764105127 )
Telemed J E Health - Older people's attitudes toward interactive voice response systems. ( 0,563763653816332 )
Int J Med Inform - Perspectives on wellness self-monitoring tools for older adults. ( 0,562942687955525 )
Telemed J E Health - Characteristics of patients who seek care via eVisits instead of office visits. ( 0,562705820801026 )
J. Med. Internet Res. - Young men, mental health, and technology: implications for service design and delivery in the digital age. ( 0,56052477675374 )
Med Decis Making - Serious health events and discontinuation of routine cancer screening. ( 0,5559773571745 )
AMIA Annu Symp Proc - Integrating public data sets for analysis of maternal airborne environmental exposures and stillbirth. ( 0,555050593226272 )
J Am Med Inform Assoc - Longitudinal analysis of pain in patients with metastatic prostate cancer using natural language processing of medical record text. ( 0,548362687601334 )
IEEE J Biomed Health Inform - Identification of the Best Anthropometric Predictors of Serum High- and Low-Density Lipoproteins Using Machine Learning. ( 0,547649325022712 )
J. Med. Internet Res. - Impact of internet use on loneliness and contact with others among older adults: cross-sectional analysis. ( 0,545588169557548 )
Int J Health Geogr - Where they live, how they play: neighborhood greenness and outdoor physical activity among preschoolers. ( 0,545549218152845 )
Int J Health Geogr - A multilevel non-hierarchical study of birth weight and socioeconomic status. ( 0,544379134697841 )
J Telemed Telecare - Use of a homecare electronic health record to find associations between patient characteristics and re-hospitalizations in patients with heart failure using telehealth. ( 0,543328680918678 )
J. Med. Internet Res. - Baby boomers' adoption of consumer health technologies: survey on readiness and barriers. ( 0,541836274248482 )
Int J Health Geogr - Mercury in fish and adverse reproductive outcomes: results from South Carolina. ( 0,539563071274939 )
Telemed J E Health - Delivering laboratory results by text message and e-mail: a survey of factors associated with conceptual acceptability among STD clinic attendees. ( 0,538446858465658 )
Int J Health Geogr - Generating GPS activity spaces that shed light upon the mobility habits of older adults: a descriptive analysis. ( 0,537955351647192 )
Telemed J E Health - Comparative effectiveness study to assess two examination modalities used to detect dental caries in preschool urban children. ( 0,537365989944189 )
J. Med. Internet Res. - Consumers' perceptions about and use of the internet for personal health records and health information exchange: analysis of the 2007 Health Information National Trends Survey. ( 0,535418558347418 )
J Telemed Telecare - Teleconsulting for minor head injury: the Piedmont experience. ( 0,533885744731863 )
J Am Med Inform Assoc - An interactive Bayesian model for prediction of lymph node ratio and survival in pancreatic cancer patients. ( 0,533108711630579 )
Telemed J E Health - A web search on environmental topics: what is the role of ranking? ( 0,532936406541977 )
BMC Med Inform Decis Mak - Increasing utilization of Internet-based resources following efforts to promote evidence-based medicine: a national study in Taiwan. ( 0,530858458770628 )
J. Med. Internet Res. - Using a geolocation social networking application to calculate the population density of sex-seeking gay men for research and prevention services. ( 0,52929934076855 )
Med Decis Making - Rating the preferences for potential harms of treatments for cardiovascular disease: a survey of community-dwelling adults. ( 0,529218006453653 )
J Am Med Inform Assoc - Depression screening via a smartphone app: cross-country user characteristics and feasibility. ( 0,527446592220023 )
J Am Med Inform Assoc - Patient-provider communication and trust in relation to use of an online patient portal among diabetes patients: The Diabetes and Aging Study. ( 0,524350298864076 )
J. Med. Internet Res. - Physician choice making and characteristics associated with using physician-rating websites: cross-sectional study. ( 0,524152683410636 )
Med Decis Making - The utility of childhood and adolescent obesity assessment in relation to adult health. ( 0,522348384568506 )
Spat Spatiotemporal Epidemiol - Maternal anemia associated with walkable distance to healthy food sources in Bronx, New York. ( 0,521739919456051 )
J. Med. Internet Res. - Predictors of retention in an online follow-up study of men who have sex with men. ( 0,520872520818859 )
Comput Math Methods Med - Standardization of Malaysian adult female nasal cavity. ( 0,518793415836302 )
Comput Methods Programs Biomed - Spectral and complexity analysis of scalp EEG characteristics for mild cognitive impairment and early Alzheimer's disease. ( 0,518793415836302 )
Telemed J E Health - Improving older adults' experience with interactive voice response systems. ( 0,518297471180661 )
Med Decis Making - Do men make informed decisions about prostate cancer screening? Baseline results from the take the wheel trial. ( 0,518097711440817 )
Comput Methods Programs Biomed - A record linkage process of a cervical cancer screening database. ( 0,518027473148282 )
Int J Health Geogr - Neighborhood food environment and body mass index among Japanese older adults: results from the Aichi Gerontological Evaluation Study (AGES). ( 0,517849689193849 )
Int J Med Inform - Older adults' perceptions of technologies aimed at falls prevention, detection or monitoring: a systematic review. ( 0,51699260525645 )
Int J Health Geogr - Spatial variability of climate effects on ischemic heart disease hospitalization rates for the period 1989-2006 in Quebec, Canada. ( 0,516131906048178 )
Spat Spatiotemporal Epidemiol - Multilevel spatiotemporal change-point models for evaluating the effect of an alcohol outlet control policy on changes in neighborhood assaultive violence rates. ( 0,516058436198785 )
Int J Health Geogr - Correlation of the ratio of metastatic to non-metastatic cancer cases with the degree of socioeconomic deprivation among Texas counties. ( 0,5152701451477 )
J. Med. Internet Res. - What are young adults saying about mental health? An analysis of Internet blogs. ( 0,512872970927901 )
BMC Med Inform Decis Mak - A novel method for studying the temporal relationship between type 2 diabetes mellitus and cancer using the electronic medical record. ( 0,512707407392299 )