Med Biol Eng Comput - Computational fluid dynamics of blood flow in coil-embolized aneurysms: effect of packing density on flow stagnation in an idealized geometry.

Tópicos

{ model(2220) cell(1177) simul(1124) }
{ blood(1257) pressur(1144) flow(957) }
{ patient(2315) diseas(1263) diabet(1191) }
{ studi(1119) effect(1106) posit(819) }
{ method(984) reconstruct(947) comput(926) }
{ implement(1333) system(1263) develop(1122) }
{ featur(3375) classif(2383) classifi(1994) }
{ risk(3053) factor(974) diseas(938) }
{ first(2504) two(1366) second(1323) }
{ framework(1458) process(801) describ(734) }
{ chang(1828) time(1643) increas(1301) }
{ can(774) often(719) complex(702) }
{ data(1737) use(1416) pattern(1282) }
{ imag(2830) propos(1344) filter(1198) }
{ imag(2675) segment(2577) method(1081) }
{ treatment(1704) effect(941) patient(846) }
{ data(1714) softwar(1251) tool(1186) }
{ studi(1410) differ(1259) use(1210) }
{ perform(1367) use(1326) method(1137) }
{ medic(1828) order(1363) alert(1069) }
{ group(2977) signific(1463) compar(1072) }
{ patient(1821) servic(1111) care(1106) }
{ health(1844) social(1437) communiti(874) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ model(3404) distribut(989) bayesian(671) }
{ imag(1947) propos(1133) code(1026) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ network(2748) neural(1063) input(814) }
{ take(945) account(800) differ(722) }
{ studi(2440) review(1878) systemat(933) }
{ motion(1329) object(1292) video(1091) }
{ assess(1506) score(1403) qualiti(1306) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ care(1570) inform(1187) nurs(1089) }
{ general(901) number(790) one(736) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ howev(809) still(633) remain(590) }
{ data(3963) clinic(1234) research(1004) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ result(1111) use(1088) new(759) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Coil embolization is performed to induce flow stagnation in cerebral aneurysms and enhance blood clot formation, thus preventing rupture and further growth. We investigated hemodynamics in differently positioned aneurysms coiled at various packing densities to determine the effective packing density in terms of flow stagnation. As a first step, hemodynamic simulations were conducted for idealized geometries of both terminal- and sidewall-type aneurysms. Porous media modeling was employed to describe blood flow in coil-embolized aneurysms. The stagnant volume ratio (SVR) was analyzed to quantify the efficacy of coil embolization. Regardless of aneurysm type and angle, SVR increased with increasing packing density, but the increase in SVR varied depending on type. For sidewall-type aneurysms, the packing density required to achieve 60?% SVR was 20?%, roughly independent of aneurysm angle; flow stagnation was achieved at low packing density. In contrast, in terminal-type aneurysms, the packing density required to achieve 60?% SVR was highly dependent on aneurysm angle, accomplishing a 20?% packing density only for lower angles. Indications are that a relatively high packing density would be required, particularly when these aneurysms are angled against the parent artery. The packing density required for flow stagnation varies depending on aneurysm type and relative position.

Resumo Limpo

coil embol perform induc flow stagnat cerebr aneurysm enhanc blood clot format thus prevent ruptur growth investig hemodynam differ posit aneurysm coil various pack densiti determin effect pack densiti term flow stagnat first step hemodynam simul conduct ideal geometri termin sidewalltyp aneurysm porous media model employ describ blood flow coilembol aneurysm stagnant volum ratio svr analyz quantifi efficaci coil embol regardless aneurysm type angl svr increas increas pack densiti increas svr vari depend type sidewalltyp aneurysm pack densiti requir achiev svr rough independ aneurysm angl flow stagnat achiev low pack densiti contrast terminaltyp aneurysm pack densiti requir achiev svr high depend aneurysm angl accomplish pack densiti lower angl indic relat high pack densiti requir particular aneurysm angl parent arteri pack densiti requir flow stagnat vari depend aneurysm type relat posit

Resumos Similares

Comput. Biol. Med. - Finite element modelling of diseased carotid bifurcations generated from in vivo computerised tomographic angiography. ( 0,787382561867077 )
Med Biol Eng Comput - The effect of angulation in abdominal aortic aneurysms: fluid-structure interaction simulations of idealized geometries. ( 0,773394545319067 )
Med Biol Eng Comput - 3D network model of NO transport in tissue. ( 0,762106140837283 )
Comput Math Methods Med - Finite element modelling of pulsatile blood flow in idealized model of human aortic arch: study of hypotension and hypertension. ( 0,760692731786794 )
Comput. Biol. Med. - A computational study of the respiratory airflow characteristics in normal and obstructed human airways. ( 0,758016082603089 )
Comput. Biol. Med. - Computational study of thermal effects of large blood vessels in human knee joint. ( 0,745896072596612 )
Comput Methods Programs Biomed - Prediction of coronary plaque location on arteries having myocardial bridge, using finite element models. ( 0,7366951348931 )
Comput. Biol. Med. - A computational pipeline for quantification of mouse myocardial stiffness parameters. ( 0,728765639361295 )
Comput Methods Programs Biomed - Numerical analysis of coronary artery bypass grafts: an over view. ( 0,725414119140853 )
Med Biol Eng Comput - Biomechanical analysis of the splenic avulsion mechanism. ( 0,721209581604822 )
Comput Math Methods Med - Fluid structural analysis of human cerebral aneurysm using their own wall mechanical properties. ( 0,720746199209931 )
Med Biol Eng Comput - The consequences of the mechanical environment of peripheral arteries for nitinol stenting. ( 0,712659362695956 )
Comput Methods Programs Biomed - Subject-specific finite element simulation of the human femur considering inhomogeneous material properties: a straightforward method and convergence study. ( 0,71221572438306 )
Comput Math Methods Med - Superficial collagen fibril modulus and pericellular fixed charge density modulate chondrocyte volumetric behaviour in early osteoarthritis. ( 0,710456070552802 )
Comput. Biol. Med. - Biological-data-based finite-element stress analysis of mandibular bone with implant-supported overdenture. ( 0,709783556650146 )
Comput. Biol. Med. - Dynamic finite element analysis and moving particle simulation of human enamel on a microscale. ( 0,705450977396064 )
Comput Math Methods Med - A literature review of the numerical analysis of abdominal aortic aneurysms treated with endovascular stent grafts. ( 0,704694416277788 )
Comput Math Methods Med - Comparative evaluation of osseointegrated dental implants based on platform-switching concept: influence of diameter, length, thread shape, and in-bone positioning depth on stress-based performance. ( 0,698163050297353 )
Comput Math Methods Med - Effect of the polydispersity of RBCs on the recovery rate of RBCs during the removal of CPAs. ( 0,694398754785016 )
Artif Intell Med - Relationship between preparation of cells for therapy and cell quality using artificial neural network analysis. ( 0,69350296821836 )
J Clin Monit Comput - Monitoring CO2 in shock states. ( 0,692695931661719 )
Med Biol Eng Comput - Effects of simulated injury on the anteroinferior glenohumeral capsule. ( 0,692447163138106 )
Comput Math Methods Med - A finite element study of micropipette aspiration of single cells: effect of compressibility. ( 0,691234831364353 )
Med Biol Eng Comput - Biomechanical comparison of fusionless growth modulation corrective techniques in pediatric scoliosis. ( 0,690227584958085 )
Med Biol Eng Comput - Generating anatomical models of the heart and the aorta from medical images for personalized physiological simulations. ( 0,687772266711874 )
Med Biol Eng Comput - A nonlinear finite element simulation of balloon expandable stent for assessment of plaque vulnerability inside a stenotic artery. ( 0,687322499299482 )
Comput Math Methods Med - Relationship between concentration difference of different density lipoproteins and shear stress in atherosclerosis. ( 0,686486486486486 )
Med Biol Eng Comput - Comparison of four mathematical models to analyze indicator-dilution curves in the coronary circulation. ( 0,681966058536815 )
Med Biol Eng Comput - Continuous flow left ventricular pump support and its effect on regional left ventricular wall stress: finite element analysis study. ( 0,679763826399728 )
Med Biol Eng Comput - Mechanical and microarchitectural analyses of cancellous bone through experiment and computer simulation. ( 0,678213574693239 )
Wiley Interdiscip Rev Syst Biol Med - Vascular tissue engineering: from in vitro to in situ. ( 0,676537422177442 )
Comput. Biol. Med. - Application of an anatomically-detailed finite element thorax model to investigate pediatric cardiopulmonary resuscitation techniques on hard bed. ( 0,675065731548362 )
IEEE Trans Vis Comput Graph - Vortical Inviscid Flows with Two-Way Solid-Fluid Coupling. ( 0,674889319768162 )
Comput. Biol. Med. - Simulation of a pulsatile non-Newtonian flow past a stenosed 2D artery with atherosclerosis. ( 0,674185944299873 )
Med Biol Eng Comput - Patient-specific finite element modeling of the Cardiokinetix Parachute(?) device: effects on left ventricular wall stress and function. ( 0,674090695819723 )
Comput Math Methods Med - CFD modelling of abdominal aortic aneurysm on hemodynamic loads using a realistic geometry with CT. ( 0,672678361840901 )
Comput Methods Programs Biomed - Computational analysis of cartilage implants based on an interpenetrated polymer network for tissue repairing. ( 0,669426906284204 )
Int J Comput Assist Radiol Surg - Surgical stent planning: simulation parameter study for models based on DICOM standards. ( 0,669236951967013 )
Med Biol Eng Comput - Computer simulation of three-dimensional plaque formation and progression in the carotid artery. ( 0,669118871521175 )
Med Biol Eng Comput - Clinically oriented real-time monitoring of the individual's risk for deep tissue injury. ( 0,66824754309697 )
Comput Math Methods Med - Pressure dynamic characteristics of pressure controlled ventilation system of a lung simulator. ( 0,667716142789065 )
Med Biol Eng Comput - Influence of ischemic core muscle fibers on surface depolarization potentials in superfused cardiac tissue preparations: a simulation study. ( 0,665332749582994 )
Med Biol Eng Comput - Multi-scale study of nanoparticle transport and deposition in tissues during an injection process. ( 0,663264072277703 )
Med Biol Eng Comput - Biomechanical modeling of brace treatment of scoliosis: effects of gravitational loads. ( 0,661922397085097 )
Med Biol Eng Comput - Mechanical behaviour and rupture of normal and pathological human ascending aortic wall. ( 0,657270618951616 )
Comput. Biol. Med. - Computational studies on strain transmission from a collagen gel construct to a cell and its internal cytoskeletal filaments. ( 0,656413751898573 )
Med Biol Eng Comput - Effects of skin wrinkles, age and wetness on mechanical loads in the stratum corneum as related to skin lesions. ( 0,656062672629857 )
Comput. Biol. Med. - Modeling chronic hepatitis B or C virus infection during antiviral therapy using an analogy to enzyme kinetics: long-term viral dynamics without rebound and oscillation. ( 0,655431272929371 )
Comput Math Methods Med - Altered knee joint mechanics in simple compression associated with early cartilage degeneration. ( 0,655272754965972 )
Int J Med Robot - Photoelastic stress analysis in blood vessel phantoms: three-dimensional visualization and saccular aneurysm with bleb. ( 0,653524108527829 )
Med Biol Eng Comput - Comparison of the influences of structural characteristics on bulk mechanical behaviour: experimental study using a bone surrogate. ( 0,65062360921276 )
Comput Math Methods Med - The effect of inhibitory neuron on the evolution model of higher-order coupling neural oscillator population. ( 0,650098226305824 )
J Med Syst - Post-operative assessment of an implant fixation in anterior cruciate ligament reconstructive surgery. ( 0,649117732691933 )
Med Biol Eng Comput - A new method to include the gravitational forces in a finite element model of the scoliotic spine. ( 0,649064398920835 )
Med Biol Eng Comput - In-silico modeling of atrial repolarization in normal and atrial fibrillation remodeled state. ( 0,648490460140678 )
Comput Methods Programs Biomed - Experiment and hydro-mechanical coupling simulation study on the human periodontal ligament. ( 0,648282925916962 )
Med Biol Eng Comput - Temporal evolution of skeletal regenerated tissue: what can mechanical investigation add to biological? ( 0,647188980586051 )
Med Biol Eng Comput - Sensitivity studies of pediatric material properties on juvenile lumbar spine responses using finite element analysis. ( 0,646464534573019 )
Comput Methods Programs Biomed - Physical modeling with orthotropic material based on harmonic fields. ( 0,64556281285299 )
Comput Math Methods Med - Quantitative imaging of young's modulus of soft tissues from ultrasound water jet indentation: a finite element study. ( 0,645285383431738 )
Comput Math Methods Med - Circadian models of serum potassium, sodium, and calcium concentrations in healthy individuals and their application to cardiac electrophysiology simulations at individual level. ( 0,644416336906829 )
Med Biol Eng Comput - Biomechanical characterisation of fresh and cadaverous human small intestine: applications for abdominal trauma. ( 0,644052243611599 )
Comput Math Methods Med - Recent advances in computational mechanics of the human knee joint. ( 0,643166974508742 )
Comput. Biol. Med. - Biomechanical simulation of various surface roughnesses and geometric designs on an immediately loaded dental implant. ( 0,642270911445002 )
Med Biol Eng Comput - The remodeling of alveolar bone supporting the mandibular first molar with different levels of periodontal attachment. ( 0,641345825854082 )
Med Biol Eng Comput - Unsteady wall shear stress analysis from image-based computational fluid dynamic aneurysm models under Newtonian and Casson rheological models. ( 0,640945247904071 )
Med Biol Eng Comput - Investigation of foot plantar pressure: experimental and numerical analysis. ( 0,640156586047717 )
Med Biol Eng Comput - Sensitivity of patient-specific vertebral finite element model from low dose imaging to material properties and loading conditions. ( 0,639909993015042 )
Med Biol Eng Comput - 3D finite element analysis on esthetic indirect dental restorations under thermal and mechanical loading. ( 0,639687457604814 )
Comput Methods Programs Biomed - A model of ventilation of the healthy human lung. ( 0,639264182775138 )
Comput Math Methods Med - Morphological measurement of living cells in methanol with digital holographic microscopy. ( 0,637766036341071 )
Med Biol Eng Comput - Effect of heterogeneities in the cellular microstructure on propagation of the cardiac action potential. ( 0,637116196336931 )
IEEE Trans Vis Comput Graph - Orientation-Preserving Rod Elements for Realtime Thin Shell Simulation. ( 0,636644195830351 )
Comput Methods Programs Biomed - Anthropometric dependence of the response of a thorax FE model under high speed loading: validation and real world accident replication. ( 0,635626342886171 )
Wiley Interdiscip Rev Syst Biol Med - Integrative approaches for modeling regulation and function of the respiratory system. ( 0,635393554021291 )
Med Biol Eng Comput - Fully coupled fluid-structure interaction model of congenital bicuspid aortic valves: effect of asymmetry on hemodynamics. ( 0,634644279574701 )
Int J Comput Assist Radiol Surg - Reality based modeling and simulation of gallbladder shape deformation using variational methods. ( 0,632376514670102 )
Comput. Biol. Med. - Wall shear stress variations and unsteadiness of pulsatile blood-like flows in 90-degree bifurcations. ( 0,631035993905012 )
Comput Math Methods Med - Research on the interaction between tubeimoside 1 and HepG2 cells using the microscopic imaging and fluorescent spectra method. ( 0,62855811033191 )
Med Biol Eng Comput - Can common adhesion molecules and microtopography affect cellular elasticity? A combined atomic force microscopy and optical study. ( 0,62634080691228 )
Comput Math Methods Med - Mathematical modeling of radiofrequency ablation for varicose veins. ( 0,624575238855677 )
Comput Math Methods Med - Simulation of arrhythmogenic effect of rogue RyRs in failing heart by using a coupled model. ( 0,623730806723499 )
Comput. Biol. Med. - Tooth fracture risk analysis based on a new finite element dental structure models using micro-CT data. ( 0,622999381823606 )
Comput. Biol. Med. - Modeling of tumor growth undergoing virotherapy. ( 0,621684147038252 )
Int J Comput Assist Radiol Surg - Multi-scale model for investigating the electrical properties and mechanical properties of liver tissue undergoing ablation. ( 0,62088355387833 )
Wiley Interdiscip Rev Syst Biol Med - Computational and experimental characterization of skin mechanics: identifying current challenges and future directions. ( 0,620418259823328 )
Med Biol Eng Comput - Biomechanical analysis of traumatic mesenteric avulsion. ( 0,619131735763185 )
Comput. Biol. Med. - Blood flow vectoring control in aortic arch using full and partial clamps. ( 0,618540348493825 )
Comput Methods Programs Biomed - A model of perfusion of the healthy human lung. ( 0,617405301393911 )
Med Biol Eng Comput - Finite element analysis of the influence of loading rate on a model of the full lumbar spine under dynamic loading conditions. ( 0,617252916115246 )
Med Biol Eng Comput - Validation efforts and flexibilities of an eight-year-old human juvenile lumbar spine using a three-dimensional finite element model. ( 0,616027928454658 )
Med Biol Eng Comput - Change of mechanical vertebrae properties due to progressive osteoporosis: combined biomechanical and finite-element analysis within a rat model. ( 0,614970836746822 )
Int J Med Robot - The effect of proximal tibial corrective osteotomy on menisci, tibia and tarsal bones: a finite element model study of tibia vara. ( 0,614906774842094 )
Comput Methods Programs Biomed - Growth plate stress distribution implications during bone development: a simple framework computational approach. ( 0,614261992922636 )
Comput. Aided Surg. - Use of finite element analysis of a Lenke type 5 adolescent idiopathic scoliosis case to assess possible surgical outcomes. ( 0,613580942078201 )
Med Biol Eng Comput - Subject-specific estimation of central aortic blood pressure via system identification: preliminary in-human experimental study. ( 0,612237564050782 )
Comput Math Methods Med - A review of the combination of experimental measurements and fibril-reinforced modeling for investigation of articular cartilage and chondrocyte response to loading. ( 0,611672408551706 )
Int J Comput Assist Radiol Surg - Quasi-linear viscoelastic modeling of arterial wall for surgical simulation. ( 0,610599842996911 )
Comput Methods Programs Biomed - A phenomenological mathematical model of the articular cartilage damage. ( 0,610184767468388 )
IEEE Trans Vis Comput Graph - Wetting of Porous Solids. ( 0,608825048110921 )