Med Biol Eng Comput - The effect of angulation in abdominal aortic aneurysms: fluid-structure interaction simulations of idealized geometries.


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Abdominal aortic aneurysm (AAA) represents a degenerative disease process of the abdominal aorta that results in dilation and permanent remodeling of the arterial wall. A fluid structure interaction (FSI) parametric study was conducted to evaluate the progression of aneurysmal disease and its possible implications on risk of rupture. Two parametric studies were conducted using (i) the iliac bifurcation angle and (ii) the AAA neck angulation. Idealized streamlined AAA geometries were employed. The simulations were carried out using both isotropic and anisotropic wall material models. The parameters were based on CT scans measurements obtained from a population of patients. The results indicate that the peak wall stresses increased with increasing iliac and neck inlet angles. Wall shear stress (WSS) and fluid pressure were analyzed and correlated with the wall stresses for both sets of studies. An adaptation response of a temporary reduction of the peak wall stresses seem to correlate to a certain extent with increasing iliac angles. For the neck angulation studies it appears that a breakdown from symmetric vortices at the AAA inlet into a single larger vortex significantly increases the wall stress. Our parametric FSI study demonstrates the adaptation response during aneurysmal disease progression and its possible effects on the AAA risk of rupture. This dependence on geometric parameters of the AAA can be used as an additional diagnostic tool to help clinicians reach informed decisions in establishing whether a risky surgical intervention is warranted.

Resumo Limpo

abdomin aortic aneurysm aaa repres degen diseas process abdomin aorta result dilat perman remodel arteri wall fluid structur interact fsi parametr studi conduct evalu progress aneurysm diseas possibl implic risk ruptur two parametr studi conduct use iliac bifurc angl ii aaa neck angul ideal streamlin aaa geometri employ simul carri use isotrop anisotrop wall materi model paramet base ct scan measur obtain popul patient result indic peak wall stress increas increas iliac neck inlet angl wall shear stress wss fluid pressur analyz correl wall stress set studi adapt respons temporari reduct peak wall stress seem correl certain extent increas iliac angl neck angul studi appear breakdown symmetr vortic aaa inlet singl larger vortex signific increas wall stress parametr fsi studi demonstr adapt respons aneurysm diseas progress possibl effect aaa risk ruptur depend geometr paramet aaa can use addit diagnost tool help clinician reach inform decis establish whether riski surgic intervent warrant

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