Med Biol Eng Comput - Finite element analysis of idealised unit cell cancellous structure based on morphological indices of cancellous bone.

Tópicos

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Resumo

Human bones can be categorised into one of two types--the compact cortical and the porous cancellous. Whilst the cortical is a solid structure macroscopically, the structure of cancellous bone is highly complex with plate-like and strut-like structures of various sizes and shapes depending on the anatomical site. Reconstructing the actual structure of cancellous bone for defect filling is highly unfeasible. However, the complex structure can be simplified into an idealised structure with similar properties. In this study, two idealised architectures were developed based on morphological indices of cancellous bone: the tetrakaidecahedral and the prismatic. The two architectures were further subdivided into two types of microstructure, the first consists of struts only and the second consists of a combination of plates and struts. The microstructures were transformed into finite element models and displacement boundary condition was applied to all four idealised cancellous models with periodic boundary conditions. Eight unit cells extracted from the actual cancellous bone obtained from micro-computed tomography were also analysed with the same boundary conditions. Young's modulus values were calculated and comparison was made between the idealised and real cancellous structures. Results showed that all models with a combination of plates and struts have higher rigidity compared to the one with struts only. Values of Young's modulus from eight unit cells of cancellous bone varied from 42 to 479 MPa with an average of 234 MPa. The prismatic architecture with plates and rods closely resemble the average stiffness of a unit cell of cancellous bone.

Resumo Limpo

human bone can categoris one two typesth compact cortic porous cancel whilst cortic solid structur macroscop structur cancel bone high complex platelik strutlik structur various size shape depend anatom site reconstruct actual structur cancel bone defect fill high unfeas howev complex structur can simplifi idealis structur similar properti studi two idealis architectur develop base morpholog indic cancel bone tetrakaidecahedr prismat two architectur subdivid two type microstructur first consist strut second consist combin plate strut microstructur transform finit element model displac boundari condit appli four idealis cancel model period boundari condit eight unit cell extract actual cancel bone obtain microcomput tomographi also analys boundari condit young modulus valu calcul comparison made idealis real cancel structur result show model combin plate strut higher rigid compar one strut valu young modulus eight unit cell cancel bone vari mpa averag mpa prismat architectur plate rod close resembl averag stiff unit cell cancel bone

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