Med Biol Eng Comput - Measurement of the local aortic stiffness by a non-invasive bioelectrical impedance technique.

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Resumo

Aortic stiffness measurement is well recognized as an independent predictor of cardiovascular mortality and morbidity. Recently, a simple method has been proposed for the evaluation of the local aortic stiffness (AoStiff) using a non-invasive bioelectrical impedance (BI) technique. This approach relies on a novel interpretation of the arterial stiffness where AoStiff is computed from the measurement of two new BI variables: (1) the local aortic flow resistance (AoRes) exerted by the drag forces onto the flow; (2) the local aortic wall distensibility (AoDist). Herein, we propose to detail and compare these three indices with the reference pulse wave velocity (PWV) measurement and the direct assessment of the aortic drag forces (DF) and distensibility (DS) obtained by the magnetic resonance imaging technique. Our results show a significant correlation between AoStiff and PWV (r = 0.79; P < 0.0001; 120 patients at rest; mean age 44 ? 16 years), and also between AoRes and DF (r = 0.95; P = 0.0011) and between AoDist and DS (r = 0.93; P = 0.0022) on eight patients at rest (mean age 52 ? 19 years). These first results suggest that local aortic stiffness can be explored reliably by the BI technique.

Resumo Limpo

aortic stiff measur well recogn independ predictor cardiovascular mortal morbid recent simpl method propos evalu local aortic stiff aostiff use noninvas bioelectr imped bi techniqu approach reli novel interpret arteri stiff aostiff comput measur two new bi variabl local aortic flow resist aor exert drag forc onto flow local aortic wall distens aodist herein propos detail compar three indic refer puls wave veloc pwv measur direct assess aortic drag forc df distens ds obtain magnet reson imag techniqu result show signific correl aostiff pwv r p patient rest mean age year also aor df r p aodist ds r p eight patient rest mean age year first result suggest local aortic stiff can explor reliabl bi techniqu

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