Med Biol Eng Comput - Effects of skin wrinkles, age and wetness on mechanical loads in the stratum corneum as related to skin lesions.

Tópicos

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Resumo

Finite element models of skin were developed to determine the effects of wetness, age, and wrinkles on mechanical strains and stresses in the stratum corneum (SC) as related to skin lesions. We modeled two geometries, young (0.12-mm-deep wrinkles) and aged (0.18-mm-deep wrinkles), and for each geometry, three loading conditions were applied (compression in a dry environment, compression and shear in dryness, and compression with shear in wetness). Effects of skin wrinkling were studied independently or while coupled with age-related mechanical property changes. For each simulation, we calculated the peak maximal shear strain and stress in the SC, peak shear stress on the skin surface, and volumetric exposure of the SC to potentially injurious shear stresses (<70 kPa). Compression and shear with wetness produced the highest skin surface loads. Volumetric exposure of aged skin to potentially injurious shear stresses was six times greater than in the young skin for these conditions. Deeper wrinkles caused elevated loads in the SC consistently for all outcome measures and independently of the age factor. Thinning and/or stiffening the SC increased both the surface and internal SC stresses. Our findings indicate that theoretically, wetness, skin aging, and/or skin wrinkling are all risk factors for skin lesions such as superficial pressure ulcers.

Resumo Limpo

finit element model skin develop determin effect wet age wrinkl mechan strain stress stratum corneum sc relat skin lesion model two geometri young mmdeep wrinkl age mmdeep wrinkl geometri three load condit appli compress dri environ compress shear dryness compress shear wet effect skin wrinkl studi independ coupl agerel mechan properti chang simul calcul peak maxim shear strain stress sc peak shear stress skin surfac volumetr exposur sc potenti injuri shear stress kpa compress shear wet produc highest skin surfac load volumetr exposur age skin potenti injuri shear stress six time greater young skin condit deeper wrinkl caus elev load sc consist outcom measur independ age factor thin andor stiffen sc increas surfac intern sc stress find indic theoret wet skin age andor skin wrinkl risk factor skin lesion superfici pressur ulcer

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