Med Biol Eng Comput - Flexible and stretchable micro-electrodes for in vitro and in vivo neural interfaces.

Tópicos

{ model(2220) cell(1177) simul(1124) }
{ network(2748) neural(1063) input(814) }
{ activ(1138) subject(705) human(624) }
{ design(1359) user(1324) use(1319) }
{ sequenc(1873) structur(1644) protein(1328) }
{ perform(1367) use(1326) method(1137) }
{ state(1844) use(1261) util(961) }
{ model(3404) distribut(989) bayesian(671) }
{ can(774) often(719) complex(702) }
{ imag(1947) propos(1133) code(1026) }
{ measur(2081) correl(1212) valu(896) }
{ method(1219) similar(1157) match(930) }
{ studi(2440) review(1878) systemat(933) }
{ motion(1329) object(1292) video(1091) }
{ framework(1458) process(801) describ(734) }
{ chang(1828) time(1643) increas(1301) }
{ data(1714) softwar(1251) tool(1186) }
{ featur(1941) imag(1645) propos(1176) }
{ howev(809) still(633) remain(590) }
{ blood(1257) pressur(1144) flow(957) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ intervent(3218) particip(2042) group(1664) }
{ patient(1821) servic(1111) care(1106) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ use(976) code(926) identifi(902) }
{ implement(1333) system(1263) develop(1122) }
{ activ(1452) weight(1219) physic(1104) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ assess(1506) score(1403) qualiti(1306) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ control(1307) perform(991) simul(935) }
{ care(1570) inform(1187) nurs(1089) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ case(1353) use(1143) diagnosi(1136) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ studi(1119) effect(1106) posit(819) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ ehr(2073) health(1662) electron(1139) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ first(2504) two(1366) second(1323) }
{ time(1939) patient(1703) rate(768) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ cancer(2502) breast(956) screen(824) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Microelectrode arrays (MEAs) are designed to monitor and/or stimulate extracellularly neuronal activity. However, the biomechanical and structural mismatch between current MEAs and neural tissues remains a challenge for neural interfaces. This article describes a material strategy to prepare neural electrodes with improved mechanical compliance that relies on thin metal film electrodes embedded in polymeric substrates. The electrode impedance of micro-electrodes on polymer is comparable to that of MEA on glass substrates. Furthermore, MEAs on plastic can be flexed and rolled offering improved structural interface with brain and nerves in vivo. MEAs on elastomer can be stretched reversibly and provide in vitro unique platforms to simultaneously investigate the electrophysiological of neural cells and tissues to mechanical stimulation. Adding mechanical compliance to MEAs is a promising vehicle for robust and reliable neural interfaces.

Resumo Limpo

microelectrod array mea design monitor andor stimul extracellular neuron activ howev biomechan structur mismatch current mea neural tissu remain challeng neural interfac articl describ materi strategi prepar neural electrod improv mechan complianc reli thin metal film electrod embed polymer substrat electrod imped microelectrod polym compar mea glass substrat furthermor mea plastic can flex roll offer improv structur interfac brain nerv vivo mea elastom can stretch revers provid vitro uniqu platform simultan investig electrophysiolog neural cell tissu mechan stimul ad mechan complianc mea promis vehicl robust reliabl neural interfac

Resumos Similares

Neural Comput - Facilitation of neuronal responses by intrinsic default mode network activity. ( 0,76997252636667 )
Comput Math Methods Med - The effect of inhibitory neuron on the evolution model of higher-order coupling neural oscillator population. ( 0,737698376728338 )
Comput Methods Programs Biomed - Drug release profile in core-shell nanofibrous structures: a study on Peppas equation and artificial neural network modeling. ( 0,733180829478206 )
Comput Math Methods Med - An approach for simulation of the muscle force modeling it by summation of motor unit contraction forces. ( 0,72199239184428 )
Med Biol Eng Comput - Effect of heterogeneities in the cellular microstructure on propagation of the cardiac action potential. ( 0,717357247596181 )
Med Biol Eng Comput - Neural oscillators triggered by loading and hip orientation can generate activation patterns at the ankle during walking in humans. ( 0,71386629912006 )
Wiley Interdiscip Rev Syst Biol Med - Integrative approaches for modeling regulation and function of the respiratory system. ( 0,710646309815485 )
Comput. Biol. Med. - Discontinuous Galerkin finite element method for solving population density functions of cortical pyramidal and thalamic neuronal populations. ( 0,709838651500275 )
Comput. Biol. Med. - Role of intracellular calcium dynamics in the short-term memory in CVM model: a simulation study. ( 0,704205824596943 )
Neural Comput - Subthreshold membrane depolarization as memory trace for perceptual learning. ( 0,702760707207696 )
Int J Comput Assist Radiol Surg - Multi-scale model for investigating the electrical properties and mechanical properties of liver tissue undergoing ablation. ( 0,702625052842248 )
Neural Comput - Deficient GABAergic gliotransmission may cause broader sensory tuning in schizophrenia. ( 0,702008026724442 )
Comput Math Methods Med - Excitation-contraction coupling between human atrial myocytes with fibroblasts and stretch activated channel current: a simulation study. ( 0,699690449240273 )
Wiley Interdiscip Rev Syst Biol Med - Neural stem and progenitor cells in health and disease. ( 0,696838262106718 )
Neural Comput - Self-organization of topographic bilinear networks for invariant recognition. ( 0,69049534762026 )
Int J Med Robot - A framework for predicting three-dimensional prostate deformation in real time. ( 0,687155704966341 )
Med Biol Eng Comput - Finite element modeling of mitral leaflet tissue using a layered shell approximation. ( 0,685460960345713 )
IEEE Trans Neural Netw Learn Syst - A Spiking Neural Simulator Integrating Event-Driven and Time-Driven Computation Schemes Using Parallel CPU-GPU Co-Processing: A Case Study. ( 0,683200528705317 )
Neural Comput - Tonically balancing intracortical excitation and inhibition by GABAergic gliotransmission. ( 0,679366537711543 )
Med Biol Eng Comput - Influence of heterogeneous and anisotropic tissue conductivity on electric field distribution in deep brain stimulation. ( 0,678099294464777 )
Neural Comput - Regulation of ambient GABA levels by neuron-glia signaling for reliable perception of multisensory events. ( 0,6765772887016 )
Neural Comput - Motor cortex microcircuit simulation based on brain activity mapping. ( 0,673424195745229 )
Comput Math Methods Med - The influence of the specimen shape and loading conditions on the parameter identification of a viscoelastic brain model. ( 0,671547218814645 )
Comput. Biol. Med. - Simulation of the microscopic process during initiation of stent thrombosis. ( 0,670835337398067 )
J Med Syst - Functional and mechanical evaluation of nerve stretch injury. ( 0,667239640107837 )
Neural Comput - The role of extracellular conductivity profiles in compartmental models for neurons: particulars for layer 5 pyramidal cells. ( 0,657270079274086 )
Med Biol Eng Comput - Intraoperative forces and moments analysis on patient head clamp during awake brain surgery. ( 0,656887415680844 )
Comput. Biol. Med. - Simulating a dual-array electrode configuration to investigate the influence of skeletal muscle fatigue following functional electrical stimulation. ( 0,654597314766412 )
Neural Comput - Ambient GABA responsible for age-related changes in multistable perception. ( 0,652402278643612 )
Med Biol Eng Comput - Temporal evolution of skeletal regenerated tissue: what can mechanical investigation add to biological? ( 0,650127781575143 )
Int J Med Robot - A physics-based algorithm for real-time simulation of electrosurgery procedures in minimally invasive surgery. ( 0,645653991805301 )
Med Biol Eng Comput - Spatiotemporal scales and links between electrical neuroimaging modalities. ( 0,645624579054822 )
Neural Comput - Spontaneous slow oscillations and sequential patterns due to short-term plasticity in a model of the cortex. ( 0,640417741622617 )
Med Biol Eng Comput - Extracting the parameters of the double-dispersion Cole bioimpedance model from magnitude response measurements. ( 0,639355853785617 )
Comput Math Methods Med - Superficial collagen fibril modulus and pericellular fixed charge density modulate chondrocyte volumetric behaviour in early osteoarthritis. ( 0,638175064681112 )
Comput Math Methods Med - Three-dimensional lower extremity joint loading in a carved ski and snowboard turn: a pilot study. ( 0,637343509505085 )
Comput. Biol. Med. - Effects of degenerated intervertebral discs on intersegmental rotations, intradiscal pressures, and facet joint forces of the whole lumbar spine. ( 0,635929436233687 )
Comput Math Methods Med - A review of the combination of experimental measurements and fibril-reinforced modeling for investigation of articular cartilage and chondrocyte response to loading. ( 0,634800984587953 )
Med Biol Eng Comput - Change of mechanical vertebrae properties due to progressive osteoporosis: combined biomechanical and finite-element analysis within a rat model. ( 0,631859817959143 )
Comput Math Methods Med - Morphological measurement of living cells in methanol with digital holographic microscopy. ( 0,630924534413959 )
Comput. Biol. Med. - Role of spiral wave pinning in inhomogeneous active media in the termination of atrial fibrillation by electrical cardioversion. ( 0,630768564409231 )
Med Biol Eng Comput - Influence of ischemic core muscle fibers on surface depolarization potentials in superfused cardiac tissue preparations: a simulation study. ( 0,630705997473164 )
Med Biol Eng Comput - Characterization of cellular elastic modulus using structure based double layer model. ( 0,630443476755247 )
Med Biol Eng Comput - 3D network model of NO transport in tissue. ( 0,627840296649534 )
Wiley Interdiscip Rev Syst Biol Med - Mitochondrial network energetics in the heart. ( 0,626944324080225 )
Int J Neural Syst - Modeling fluctuations in default-mode brain network using a spiking neural network. ( 0,625740725247093 )
Comput Methods Programs Biomed - An FDTD-based computer simulation platform for shock wave propagation in electrohydraulic lithotripsy. ( 0,625709838218307 )
Int J Comput Assist Radiol Surg - Surgical stent planning: simulation parameter study for models based on DICOM standards. ( 0,625308294230668 )
Med Biol Eng Comput - Estimation of the retainer height biomechanical contribution in posterior resin-bonded fixed partial dentures: a structural-thermal coupled finite element analysis. ( 0,624117040409741 )
Med Biol Eng Comput - Optical monitoring of neural networks evoked by focal electrical stimulation on microelectrode arrays using FM dyes. ( 0,623928705645941 )
Comput. Biol. Med. - Estimation of saline-mixed tissue conductivity and ablation lesion size. ( 0,623444912380476 )
Med Biol Eng Comput - Validation efforts and flexibilities of an eight-year-old human juvenile lumbar spine using a three-dimensional finite element model. ( 0,622764572667449 )
Comput Methods Programs Biomed - A phenomenological mathematical model of the articular cartilage damage. ( 0,620186053274979 )
Comput. Biol. Med. - Computational studies on strain transmission from a collagen gel construct to a cell and its internal cytoskeletal filaments. ( 0,619902839858249 )
Comput Methods Programs Biomed - Optimal bone density distributions: numerical analysis of the osteocyte spatial influence in bone remodeling. ( 0,619116018829117 )
Comput Math Methods Med - Dynamics of posttranslational modifications of p53. ( 0,619038751999113 )
Wiley Interdiscip Rev Syst Biol Med - A systems biology approach to synovial joint lubrication in health, injury, and disease. ( 0,618992745626042 )
Neural Comput - Synaptic scaling stabilizes persistent activity driven by asynchronous neurotransmitter release. ( 0,618548064166869 )
Med Biol Eng Comput - Modeling and experimental methods to predict oxygen distribution in bone defects following cell transplantation. ( 0,618491473646721 )
Med Biol Eng Comput - Sensitivity studies of pediatric material properties on juvenile lumbar spine responses using finite element analysis. ( 0,618271064818733 )
Med Biol Eng Comput - A three-dimensional finite element model of the cervical spine: an investigation of whiplash injury. ( 0,617400775455861 )
Brief. Bioinformatics - Letter to the editor: Current progress in patient-specific modeling by Neal and Kerckhoffs (2010). ( 0,616677065300054 )
Int J Neural Syst - A new work mechanism on neuronal activity. ( 0,616674719595661 )
Comput Math Methods Med - Modeling the chemoelectromechanical behavior of skeletal muscle using the parallel open-source software library OpenCMISS. ( 0,616363627312657 )
Med Biol Eng Comput - Strain rate-dependent viscohyperelastic constitutive modeling of bovine liver tissue. ( 0,615521957982075 )
Med Biol Eng Comput - Mechanical and microarchitectural analyses of cancellous bone through experiment and computer simulation. ( 0,615463309188925 )
Int J Med Robot - Comparison of the biomechanical effects of pertrochanteric fixator and dynamic hip screw on an intertrochanteric femoral fracture using the finite element method. ( 0,614875608328139 )
Med Biol Eng Comput - Clinically oriented real-time monitoring of the individual's risk for deep tissue injury. ( 0,613306592651772 )
Med Biol Eng Comput - Estimation of flexible needle deflection in layered soft tissues with different elastic moduli. ( 0,613217670653912 )
Med Biol Eng Comput - Biomechanical analysis of the splenic avulsion mechanism. ( 0,612786070499073 )
Wiley Interdiscip Rev Syst Biol Med - In silico models of bone remodeling from macro to nano--from organ to cell. ( 0,611144186650494 )
Int J Neural Syst - A neuron-based time-optimal controller of horizontal saccadic eye movements. ( 0,610953636244221 )
Comput Methods Programs Biomed - Experiment and hydro-mechanical coupling simulation study on the human periodontal ligament. ( 0,610138778992448 )
J Chem Inf Model - Computational modeling of kinesin stepping. ( 0,609589967347625 )
Neural Comput - Spike-timing-dependent construction. ( 0,60888274850293 )
Comput. Biol. Med. - Biological-data-based finite-element stress analysis of mandibular bone with implant-supported overdenture. ( 0,608601767268184 )
Med Biol Eng Comput - Mixed-signal template-based reduction scheme for stimulus artifact removal in electrical stimulation. ( 0,608047209901137 )
Comput. Biol. Med. - Protein transport in the connecting cilium of a photoreceptor cell: modeling the effects of bidirectional protein transitions between the diffusion-driven and motor-driven kinetic states. ( 0,606433246730873 )
Comput Math Methods Med - Voxel scale complex networks of functional connectivity in the rat brain: neurochemical state dependence of global and local topological properties. ( 0,604955940646759 )
Comput. Biol. Med. - Biomechanical simulation of various surface roughnesses and geometric designs on an immediately loaded dental implant. ( 0,604661772897469 )
Comput Biol Chem - Modeling of tumor growth in dendritic cell-based immunotherapy using artificial neural networks. ( 0,603019067821755 )
Comput. Biol. Med. - Design, analysis and verification of a knee joint oncological prosthesis finite element model. ( 0,602937900594194 )
Med Biol Eng Comput - 3D finite element analysis on esthetic indirect dental restorations under thermal and mechanical loading. ( 0,602033431087268 )
Med Biol Eng Comput - Multi-scale study of nanoparticle transport and deposition in tissues during an injection process. ( 0,601862367940241 )
Int J Comput Assist Radiol Surg - NiftySim: A GPU-based nonlinear finite element package for simulation of soft tissue biomechanics. ( 0,601165897865082 )
Wiley Interdiscip Rev Syst Biol Med - How changes in fibril-level organization correlate with the macrolevel behavior of articular cartilage. ( 0,596831802150452 )
Comput. Biol. Med. - Application of an anatomically-detailed finite element thorax model to investigate pediatric cardiopulmonary resuscitation techniques on hard bed. ( 0,59674281685584 )
Med Biol Eng Comput - Deformation and pressure propagation in deep tissue during mechanical painful pressure stimulation. ( 0,596431494720464 )
Comput. Biol. Med. - Mathematical model of the coagulation in the bone-dental implant interface. ( 0,594571799701264 )
Med Biol Eng Comput - Comparison of spinal cord stimulation profiles from intra- and extradural electrode arrangements by finite element modelling. ( 0,594153265360817 )
Med Biol Eng Comput - Improved numerical approach for electrical modeling of biological cell clusters. ( 0,593973011986979 )
Comput Methods Programs Biomed - Monte Carlo method for photon heating using temperature-dependent optical properties. ( 0,593772930043545 )
Med Biol Eng Comput - Continuous flow left ventricular pump support and its effect on regional left ventricular wall stress: finite element analysis study. ( 0,593624200963901 )
Comput Methods Programs Biomed - Anthropometric dependence of the response of a thorax FE model under high speed loading: validation and real world accident replication. ( 0,593338498443896 )
Neural Comput - Signal-tuned Gabor functions as models for stimulus-dependent cortical receptive fields. ( 0,592470058260582 )
Med Biol Eng Comput - Finite element analysis of the influence of loading rate on a model of the full lumbar spine under dynamic loading conditions. ( 0,592350279848599 )
Med Biol Eng Comput - Biomechanical characterisation of fresh and cadaverous human small intestine: applications for abdominal trauma. ( 0,592089834764402 )
Med Biol Eng Comput - Can common adhesion molecules and microtopography affect cellular elasticity? A combined atomic force microscopy and optical study. ( 0,592089834764402 )
Comput Math Methods Med - Quantitative imaging of young's modulus of soft tissues from ultrasound water jet indentation: a finite element study. ( 0,592013840674716 )
Comput Math Methods Med - A finite element study of micropipette aspiration of single cells: effect of compressibility. ( 0,591952765457499 )