Med Decis Making - Bayesian inference for comorbid disease risks using marginal disease risks and correlation information from a separate source.

Tópicos

{ patient(2315) diseas(1263) diabet(1191) }
{ estim(2440) model(1874) function(577) }
{ risk(3053) factor(974) diseas(938) }
{ cost(1906) reduc(1198) effect(832) }
{ can(981) present(881) function(850) }
{ studi(1119) effect(1106) posit(819) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1452) weight(1219) physic(1104) }
{ error(1145) method(1030) estim(1020) }
{ care(1570) inform(1187) nurs(1089) }
{ case(1353) use(1143) diagnosi(1136) }
{ model(3404) distribut(989) bayesian(671) }
{ measur(2081) correl(1212) valu(896) }
{ compound(1573) activ(1297) structur(1058) }
{ blood(1257) pressur(1144) flow(957) }
{ state(1844) use(1261) util(961) }
{ detect(2391) sensit(1101) algorithm(908) }
{ chang(1828) time(1643) increas(1301) }
{ data(3963) clinic(1234) research(1004) }
{ health(3367) inform(1360) care(1135) }
{ use(1733) differ(960) four(931) }
{ can(774) often(719) complex(702) }
{ data(1737) use(1416) pattern(1282) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ take(945) account(800) differ(722) }
{ method(1557) propos(1049) approach(1037) }
{ control(1307) perform(991) simul(935) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ spatial(1525) area(1432) region(1030) }
{ patient(2837) hospit(1953) medic(668) }
{ use(2086) technolog(871) perceiv(783) }
{ use(976) code(926) identifi(902) }
{ implement(1333) system(1263) develop(1122) }
{ method(2212) result(1239) propos(1039) }
{ imag(1947) propos(1133) code(1026) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ studi(2440) review(1878) systemat(933) }
{ motion(1329) object(1292) video(1091) }
{ assess(1506) score(1403) qualiti(1306) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ problem(2511) optim(1539) algorithm(950) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ data(1714) softwar(1251) tool(1186) }
{ design(1359) user(1324) use(1319) }
{ model(2220) cell(1177) simul(1124) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ howev(809) still(633) remain(590) }
{ studi(1410) differ(1259) use(1210) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ perform(1367) use(1326) method(1137) }
{ record(1888) medic(1808) patient(1693) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ research(1218) medic(880) student(794) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ first(2504) two(1366) second(1323) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ survey(1388) particip(1329) question(1065) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ method(1969) cluster(1462) data(1082) }

Resumo

CKGROUND: Public health interventions are increasingly being evaluated for their cost-effectiveness. Such interventions act 'upstream' on the determinants of ill health and commonly reduce the incidence of several diseases. Diseases that share determinants are usually correlated at an individual level, which we observe as comorbidity. This paper is motivated by the problem of estimating comorbid disease state risks when only single disease risk estimates are available.METHODS: A case study is presented based on a physical activity cost-effectiveness model. The correlation between the risk of coronary heart disease, stroke and diabetes is estimated from cross sectional data using a Bayesian multivariate probit model. This is then combined with disease specific marginal baseline risks and intervention effects to give comorbid disease state risks. The expected numbers of QALYs gained through avoiding the comorbid states is estimated from disease specific utility data under a range of assumptions. Finally, the incremental benefit of physical activity is calculated under these utility assumptions. The difference in incremental benefit due to the intervention's impact on reducing or increasing the disease risk correlations is explored in a sensitivity analysis.RESULTS: If comorbidity is not taken into account, incremental benefit is overestimated compared with all scenarios in which the comorbidity is included in the model. Overestimation is greatest when physical activity is assumed to reduce disease state co-occurrence as well as disease risk.CONCLUSIONS: The proposed method reduces overestimation of benefit and allows the sensitivity to different assumptions about the correlation between disease risks to be determined.

Resumo Limpo

ckground public health intervent increas evalu costeffect intervent act upstream determin ill health common reduc incid sever diseas diseas share determin usual correl individu level observ comorbid paper motiv problem estim comorbid diseas state risk singl diseas risk estim availablemethod case studi present base physic activ costeffect model correl risk coronari heart diseas stroke diabet estim cross section data use bayesian multivari probit model combin diseas specif margin baselin risk intervent effect give comorbid diseas state risk expect number qali gain avoid comorbid state estim diseas specif util data rang assumpt final increment benefit physic activ calcul util assumpt differ increment benefit due intervent impact reduc increas diseas risk correl explor sensit analysisresult comorbid taken account increment benefit overestim compar scenario comorbid includ model overestim greatest physic activ assum reduc diseas state cooccurr well diseas riskconclus propos method reduc overestim benefit allow sensit differ assumpt correl diseas risk determin

Resumos Similares

AMIA Annu Symp Proc - Race and medication adherence and glycemic control: findings from an operational health information exchange. ( 0,681300714833845 )
Med Decis Making - Simulation of quality-adjusted survival in chronic diseases: an application in type 2 diabetes. ( 0,648888293861012 )
Comput Methods Programs Biomed - Markov Chain Monte Carlo simulation for projection of end stage renal disease patients in Greece. ( 0,644529713323247 )
Comput Methods Programs Biomed - Prediction of the hemoglobin level in hemodialysis patients using machine learning techniques. ( 0,633922426519073 )
J. Med. Internet Res. - Clinical effects of home telemonitoring in the context of diabetes, asthma, heart failure and hypertension: a systematic review. ( 0,633444627543426 )
Telemed J E Health - Prevalence and severity of diabetic retinopathy in Northwest Cameroon as identified by teleophthalmology. ( 0,632439325104209 )
BMC Med Inform Decis Mak - An algorithm to identify patients with treated type 2 diabetes using medico-administrative data. ( 0,630033283591441 )
J Am Med Inform Assoc - Cost-effectiveness of a shared computerized decision support system for diabetes linked to electronic medical records. ( 0,617181595065611 )
Perspect Health Inf Manag - Registry-based diabetes risk detection schema for the systematic identification of patients at risk for diabetes in West Virginia primary care centers. ( 0,608882412755263 )
Methods Inf Med - Spatial repolarization heterogeneity and survival in Chagas disease. ( 0,60302024967921 )
Spat Spatiotemporal Epidemiol - Spatial patterns in surveillance data during control of Salmonella Dublin in bovine dairy herds in Jutland, Denmark 2003-2009. ( 0,599886573231231 )
Res Synth Methods - Combining study outcome measures using dominance adjusted weights. ( 0,593313797314903 )
Comput. Biol. Med. - Identification of a model of non-esterified fatty acids dynamics through genetic algorithms: the case of women with a history of gestational diabetes. ( 0,585262834752364 )
AMIA Annu Symp Proc - Divisive Hierarchical Clustering towards Identifying Clinically Significant Pre-Diabetes Subpopulations. ( 0,582493037272187 )
Comput Methods Programs Biomed - Estimating insulin sensitivity from glucose levels only: Use of a non-linear mixed effects approach and maximum a posteriori (MAP) estimation. ( 0,580026476336125 )
Comput. Biol. Med. - A hybrid diagnosis model for determining the types of the liver disease. ( 0,578843188378001 )
Med Decis Making - Can life expectancy and QALYs be improved by a framework for deciding whether to apply clinical guidelines to patients with severe comorbid disease? ( 0,578632401881116 )
J Am Med Inform Assoc - Personal health records and hypertension control: a randomized trial. ( 0,57814656647182 )
BMC Med Inform Decis Mak - Type 2 diabetes genetic association database manually curated for the study design and odds ratio. ( 0,578036060717553 )
Comput Methods Programs Biomed - The Lindley distribution applied to competing risks lifetime data. ( 0,576616037658499 )
AMIA Annu Symp Proc - The Impact of HIT on Cost and Quality in Patient-Centered Medical Home Practices. ( 0,575634021336981 )
Lifetime Data Anal - Estimation of cumulative incidence functions when the lifetime distributions are uniformly stochastically ordered. ( 0,572377439181731 )
Telemed J E Health - Shared care combined with telecare improves glycemic control of diabetic patients in a rural underserved community. ( 0,568711880802119 )
Med Decis Making - Do different methods of modeling statin treatment effectiveness influence the optimal decision? ( 0,567684283438039 )
Lifetime Data Anal - Missing genetic information in case-control family data with general semi-parametric shared frailty model. ( 0,567163483592394 )
Med Decis Making - Modeling and calibration for exposure to time-varying, modifiable risk factors: the example of smoking behavior in India. ( 0,567043360284962 )
Comput Methods Programs Biomed - Historical data enhances safety supervision system performance in T1DM insulin therapy risk management. ( 0,566678303037512 )
Comput Methods Programs Biomed - Optimal robust control of drug delivery in cancer chemotherapy: a comparison between three control approaches. ( 0,565896022561805 )
J Am Med Inform Assoc - Predicting changes in hypertension control using electronic health records from a chronic disease management program. ( 0,565683008854581 )
Med Biol Eng Comput - A metric for the stiffness of calcified aortic valves using a combined computational and experimental approach. ( 0,565257861901945 )
Comput Methods Programs Biomed - Model based period analysis of absolute and relative survival with R: data preparation, model fitting and derivation of survival estimates. ( 0,565162703212437 )
Lifetime Data Anal - Nonparametric estimation with recurrent competing risks data. ( 0,564826579027789 )
Telemed J E Health - The empirical foundations of telemedicine interventions for chronic disease management. ( 0,562292833254388 )
Comput. Biol. Med. - A hierarchical Bayesian framework to infer the progression level to diabetes based on deficient clinical data. ( 0,560002047770641 )
Lifetime Data Anal - Censored quantile regression for residual lifetimes. ( 0,559087902969579 )
Lifetime Data Anal - A functional inference for multivariate current status data with mismeasured covariate. ( 0,558860040489358 )
Telemed J E Health - Development and evaluation of a Web-based tool to estimate type 2 diabetes risk: Diab_Alert. ( 0,556466705696 )
AMIA Annu Symp Proc - A Comparison of Data Driven-based Measures of Adherence to Oral Hypoglycemic Agents in Medicaid Patients. ( 0,553722798194196 )
J Telemed Telecare - Telemedical home-monitoring of diabetic foot disease using photographic foot imaging--a feasibility study. ( 0,553552181460404 )
Med Decis Making - Nutritional policy changes in the supplemental nutrition assistance program: a microsimulation and cost-effectiveness analysis. ( 0,553516080229426 )
Comput. Biol. Med. - A hybrid intelligent system for diagnosing microalbuminuria in type 2 diabetes patients without having to measure urinary albumin. ( 0,553319598969417 )
AMIA Annu Symp Proc - Feasibility of mobile phone-based management of chronic illness. ( 0,552873430988536 )
J Telemed Telecare - Meta-analysis and meta-regression of telehealth programmes for patients with chronic heart failure. ( 0,551463675464783 )
Lifetime Data Anal - Regression analysis of informative current status data with the additive hazards model. ( 0,551303944056466 )
BMC Med Inform Decis Mak - The chronic kidney disease model: a general purpose model of disease progression and treatment. ( 0,550641274906943 )
Appl Clin Inform - Care everywhere, a point-to-point HIE tool: utilization and impact on patient care in the ED. ( 0,550160481995657 )
J Telemed Telecare - Cost-utility analysis of a telehealth programme for patients with severe chronic obstructive pulmonary disease treated with long-term oxygen therapy. ( 0,549892276315978 )
Telemed J E Health - One-year efficacy and safety of the telehealth system in poorly controlled type 2 diabetic patients receiving insulin therapy. ( 0,549372036960208 )
Lifetime Data Anal - Maximum likelihood analysis of semicompeting risks data with semiparametric regression models. ( 0,548281135613573 )
Med Decis Making - Identification of a multistate continuous-time nonhomogeneous Markov chain model for patients with decreased renal function. ( 0,547727612831279 )
Comput Math Methods Med - Implementation of predictive data mining techniques for identifying risk factors of early AVF failure in hemodialysis patients. ( 0,547427143259063 )
Lifetime Data Anal - Evaluating incremental values from new predictors with net reclassification improvement in survival analysis. ( 0,544714170759486 )
Brief. Bioinformatics - Using cross-validation to evaluate predictive accuracy of survival risk classifiers based on high-dimensional data. ( 0,543024527108067 )
Lifetime Data Anal - Competing risks with missing covariates: effect of haplotypematch on hematopoietic cell transplant patients. ( 0,542402265077747 )
IEEE Trans Image Process - On high-order denoising models and fast algorithms for vector-valued images. ( 0,540603896726925 )
J Am Med Inform Assoc - Online disease management of diabetes: engaging and motivating patients online with enhanced resources-diabetes (EMPOWER-D), a randomized controlled trial. ( 0,540412969913466 )
Int J Med Inform - Online self-management interventions for chronically ill patients: cognitive impairment and technology issues. ( 0,537425306825494 )
J. Med. Internet Res. - The effects on health behavior and health outcomes of Internet-based asynchronous communication between health providers and patients with a chronic condition: a systematic review. ( 0,531618082515618 )
Lifetime Data Anal - Robust methods to improve efficiency and reduce bias in estimating survival curves in randomized clinical trials. ( 0,531040874686698 )
Lifetime Data Anal - Estimating heritability for cause specific mortality based on twin studies. ( 0,530532813635185 )
J Med Syst - An assessment of patient behavior over time-periods: a case study of managing type 2 diabetes through blood glucose readings and insulin doses. ( 0,529946681959762 )
Med Decis Making - Vaccinating to help ourselves and others. ( 0,529523402561251 )
Comput Methods Programs Biomed - Analysis of multiple linear regression algorithms used for respiratory mechanics monitoring during artificial ventilation. ( 0,52948930839922 )
J. Med. Internet Res. - Perceptions of successful cues to action and opportunities to augment behavioral triggers in diabetes self-management: qualitative analysis of a mobile intervention for low-income Latinos with diabetes. ( 0,529319932759416 )
J. Med. Internet Res. - A smart web aid for preventing diabetes in rural China: preliminary findings and lessons. ( 0,529217352456 )
Telemed J E Health - A novel telemonitoring device for improving diabetes control: protocol and results from a randomized clinical trial. ( 0,528953312264791 )
J Med Syst - Developing a web 2.0 diabetes care support system with evaluation from care provider perspectives. ( 0,522739423319959 )
Med Decis Making - Balancing clinical experience in outpatient residency training. ( 0,519985504879609 )
Med Biol Eng Comput - A robust sliding mode controller with internal model for closed-loop artificial pancreas. ( 0,51911718331016 )
Lifetime Data Anal - Additive-multiplicative rates model for recurrent events. ( 0,518134553171546 )
J. Med. Internet Res. - Cost-utility analysis of the EVOLVO study on remote monitoring for heart failure patients with implantable defibrillators: randomized controlled trial. ( 0,517959707663735 )
J. Med. Internet Res. - Design of an mHealth app for the self-management of adolescent type 1 diabetes: a pilot study. ( 0,51787490445501 )
Comput Methods Programs Biomed - Machine learning algorithms and forced oscillation measurements to categorise the airway obstruction severity in chronic obstructive pulmonary disease. ( 0,517443487613835 )
Med Biol Eng Comput - The effect of angulation in abdominal aortic aneurysms: fluid-structure interaction simulations of idealized geometries. ( 0,516894389398511 )
AMIA Annu Symp Proc - Spatial analysis in support of community health intervention strategies. ( 0,515112090880575 )
Med Decis Making - Bias associated with failing to incorporate dependence on event history in Markov models. ( 0,514977523153365 )
Int J Med Inform - An evolutionary-fuzzy DSS for assessing health status in multiple sclerosis disease. ( 0,514795262477632 )
Lifetime Data Anal - Efficient estimation of the distribution of time to composite endpoint when some endpoints are only partially observed. ( 0,514622163059385 )
Med Decis Making - Predicting Liver Transplant Capacity Using Discrete Event Simulation. ( 0,513390142594309 )
Telemed J E Health - Smartphone interventions for long-term health management of chronic diseases: an integrative review. ( 0,513305315852763 )
Med Decis Making - Clarifying differences in natural history between models of screening: the case of colorectal cancer. ( 0,513033712152054 )
Methods Inf Med - Assessing frequency domain causality in cardiovascular time series with instantaneous interactions. ( 0,51260083757918 )
Med Decis Making - Eliciting benefit-risk preferences and probability-weighted utility using choice-format conjoint analysis. ( 0,512482631672445 )
Health Informatics J - Is routine hospital episode data sufficient for identifying individuals with chronic kidney disease? A comparison study with laboratory data. ( 0,512074947567756 )
IEEE J Biomed Health Inform - Integration of Personalized Healthcare Pathways in an ICT platform for Diabetes Management: a small-scale exploratory study. ( 0,510886009470495 )
Med Decis Making - The Impact of Uncertainty in Barrett's Esophagus Progression Rates on Hypothetical Screening and Treatment Decisions. ( 0,510610817954455 )
Lifetime Data Anal - On collapsibility and confounding bias in Cox and Aalen regression models. ( 0,50947138166531 )
Comput. Biol. Med. - Reduced-rule based expert system by the simplification of logic functions for the diagnosis of diabetes. ( 0,509351845341417 )
Comput Math Methods Med - Risk-adjusted mortality: problems and possibilities. ( 0,509049277692076 )
Lifetime Data Anal - Events per variable for risk differences and relative risks using pseudo-observations. ( 0,508286208374834 )
Med Decis Making - Methods for estimating subgroup effects in cost-effectiveness analyses that use observational data. ( 0,507918592252749 )
J Biomed Inform - glUCModel: a monitoring and modeling system for chronic diseases applied to diabetes. ( 0,507492367503796 )
Telemed J E Health - Asynchronous virtual visits for the follow-up of chronic conditions. ( 0,507357552567732 )
Lifetime Data Anal - Estimating treatment effects on the marginal recurrent event mean in the presence of a terminating event. ( 0,506659101442971 )
Lifetime Data Anal - Recurrent first hitting times in Wiener diffusion under several observation schemes. ( 0,505833682795965 )
J Med Syst - The correlation of laboratory tests and Sympathetic Skin Response parameters by using artificial neural networks in fibromyalgia patients. ( 0,505247757925556 )
Comput. Biol. Med. - Simple reaction times and performance in the detection of visual stimuli of patients with diabetes. ( 0,504986755863545 )
BMC Med Inform Decis Mak - User-centered design of a web-based self-management site for individuals with type 2 diabetes - providing a sense of control and community. ( 0,504385630085778 )
Med Decis Making - Time series model to predict burden of viral respiratory illness on a pediatric intensive care unit. ( 0,503662517889984 )
Comput Math Methods Med - Resistance training exercise program for intervention to enhance gait function in elderly chronically ill patients: multivariate multiscale entropy for center of pressure signal analysis. ( 0,502447189572154 )