Methods Inf Med - Signal interpretation from low-dosage acquisition. An investigation for computed tomographic imaging.

Tópicos

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Resumo

JECTIVES: This paper focuses on how we could analyze and interpret filtered back-projection reconstructed signals from low-dose computed tomographic (CT) imaging systems. There exists a growing imbalance between dosage reduction and effective signal interpretation. At the same time, low-dose applications are undergoing alarming growth.METHODS: This paper interprets filtered back-projection images in low-dose CT systems and details the possible properties of the artifacts. The interpretation leads to design of a new multi-image filtered back-projection approach that allows artifacts to be effectively identified across multiple images. We use this approach as a building block to propose a new reconstruction method that enables effective artifacts reduction and efficient implementation.RESULTS: Experiments with both clinical and simulated low-dose images demonstrate the validity and effectiveness of the proposed approach.CONCLUSIONS: This study discusses a new FBP-based reconstruction approach based on signal interpretation from low-dosage acquisition. This method uses multiple filtered back-projection images from projection subsets to provide clues for distinguishing underlying clinical structure from artifacts. A framework is derived for effective signal interpretation and artifacts reduction. It requires no hardware change and a minimum amount of extra software support compared with current CT systems. Clinical and simulated low-dose CT scans demonstrated effectiveness of the proposed method.

Resumo Limpo

jectiv paper focus analyz interpret filter backproject reconstruct signal lowdos comput tomograph ct imag system exist grow imbal dosag reduct effect signal interpret time lowdos applic undergo alarm growthmethod paper interpret filter backproject imag lowdos ct system detail possibl properti artifact interpret lead design new multiimag filter backproject approach allow artifact effect identifi across multipl imag use approach build block propos new reconstruct method enabl effect artifact reduct effici implementationresult experi clinic simul lowdos imag demonstr valid effect propos approachconclus studi discuss new fbpbase reconstruct approach base signal interpret lowdosag acquisit method use multipl filter backproject imag project subset provid clue distinguish under clinic structur artifact framework deriv effect signal interpret artifact reduct requir hardwar chang minimum amount extra softwar support compar current ct system clinic simul lowdos ct scan demonstr effect propos method

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