Methods Inf Med - Quantifying changes in EEG complexity induced by photic stimulation.

Tópicos

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Resumo

JECTIVES: This study aims to characterize EEG complexity, measured as the prediction error resulting from nonlinear prediction, in healthy humans during photic stimulation.METHODS: EEGs were recorded from 15 subjects with eyes closed (EC) and eyes open (EO), during the baseline condition and during stroboscopic photic stimulation (PS) at 5, 10, and 15 Hz. The mean squared prediction error (MSPE) resulting from nearest neighbor local linear prediction was taken as complexity index. Complexity maps were generated interpolating the MSPE index over a schematic scalp representation.RESULTS: Statistical analysis revealed that: i) EEG shows good predictability in all conditions and seems to be well explained by a linear stochastic process; ii) the complexity is lower with EC than with EO and increases significantly during PS, to a lesser extent during 10 Hz stimulation; iii) significant differences of EEG complexity are detectable between anterior-central and posterior scalp regions.CONCLUSIONS: Changes in EEG complexity during PS can be successfully assessed using nonlinear prediction. The observed modifications in the patterns of complexity seem to reflect neurophysiological behaviors and suggest future applicability of the method in clinical settings.

Resumo Limpo

jectiv studi aim character eeg complex measur predict error result nonlinear predict healthi human photic stimulationmethod eeg record subject eye close ec eye open eo baselin condit stroboscop photic stimul ps hz mean squar predict error mspe result nearest neighbor local linear predict taken complex index complex map generat interpol mspe index schemat scalp representationresult statist analysi reveal eeg show good predict condit seem well explain linear stochast process ii complex lower ec eo increas signific ps lesser extent hz stimul iii signific differ eeg complex detect anteriorcentr posterior scalp regionsconclus chang eeg complex ps can success assess use nonlinear predict observ modif pattern complex seem reflect neurophysiolog behavior suggest futur applic method clinic set

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