Methods Inf Med - Regularization for generalized additive mixed models by likelihood-based boosting.

Tópicos

{ estim(2440) model(1874) function(577) }
{ model(3480) simul(1196) paramet(876) }
{ structur(1116) can(940) graph(676) }
{ model(3404) distribut(989) bayesian(671) }
{ activ(1452) weight(1219) physic(1104) }
{ general(901) number(790) one(736) }
{ model(2341) predict(2261) use(1141) }
{ result(1111) use(1088) new(759) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2675) segment(2577) method(1081) }
{ take(945) account(800) differ(722) }
{ sequenc(1873) structur(1644) protein(1328) }
{ howev(809) still(633) remain(590) }
{ studi(1410) differ(1259) use(1210) }
{ analysi(2126) use(1163) compon(1037) }
{ can(774) often(719) complex(702) }
{ extract(1171) text(1153) clinic(932) }
{ perform(1367) use(1326) method(1137) }
{ model(2656) set(1616) predict(1553) }
{ cost(1906) reduc(1198) effect(832) }
{ sampl(1606) size(1419) use(1276) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ imag(2830) propos(1344) filter(1198) }
{ studi(2440) review(1878) systemat(933) }
{ motion(1329) object(1292) video(1091) }
{ concept(1167) ontolog(924) domain(897) }
{ data(1714) softwar(1251) tool(1186) }
{ control(1307) perform(991) simul(935) }
{ data(3963) clinic(1234) research(1004) }
{ perform(999) metric(946) measur(919) }
{ import(1318) role(1303) understand(862) }
{ visual(1396) interact(850) tool(830) }
{ studi(1119) effect(1106) posit(819) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ monitor(1329) mobil(1314) devic(1160) }
{ patient(2837) hospit(1953) medic(668) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ activ(1138) subject(705) human(624) }
{ patient(1821) servic(1111) care(1106) }
{ can(981) present(881) function(850) }
{ high(1669) rate(1365) level(1280) }
{ method(2212) result(1239) propos(1039) }
{ imag(1947) propos(1133) code(1026) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ method(1219) similar(1157) match(930) }
{ network(2748) neural(1063) input(814) }
{ patient(2315) diseas(1263) diabet(1191) }
{ assess(1506) score(1403) qualiti(1306) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ learn(2355) train(1041) set(1003) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ method(1557) propos(1049) approach(1037) }
{ design(1359) user(1324) use(1319) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ risk(3053) factor(974) diseas(938) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ compound(1573) activ(1297) structur(1058) }
{ blood(1257) pressur(1144) flow(957) }
{ health(3367) inform(1360) care(1135) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ data(2317) use(1299) case(1017) }
{ signal(2180) analysi(812) frequenc(800) }
{ group(2977) signific(1463) compar(1072) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ time(1939) patient(1703) rate(768) }
{ use(2086) technolog(871) perceiv(783) }
{ health(1844) social(1437) communiti(874) }
{ cancer(2502) breast(956) screen(824) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ implement(1333) system(1263) develop(1122) }
{ survey(1388) particip(1329) question(1065) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ method(1969) cluster(1462) data(1082) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

JECTIVE: With the emergence of semi- and nonparametric regression the generalized linear mixed model has been extended to account for additive predictors. However, available fitting methods fail in high dimensional settings where many explanatory variables are present. We extend the concept of boosting to generalized additive mixed models and present an appropriate algorithm that uses two different approaches for the fitting procedure of the variance components of the random effects.METHODS: The main tool developed is likelihood-based componentwise boosting that enforces variable selection in generalized additive mixed models. In contrast to common procedures they can be used in high-dimensional settings where many covariates are available and the form of the influence is unknown. The complexity of the resulting estimators is determined by information criteria. The performance of the methods is investigated in simulation studies for binary and Poisson responses with comparisons to alternative approaches and it is applied to clinical real world data.RESULTS: Simulations show that the proposed methods are considerably more stable and more accurate in estimating the regression function than the conventional approach, especially when a large number of predictors is available. The methods also produce reasonable results in applications to real data sets, which is illustrated by the Multicenter AIDS Cohort Study.CONCLUSIONS: The boosting algorithm allows to extract relevant predictors in generalized additive mixed models. It works in high-dimensional settings and is very stable.

Resumo Limpo

jectiv emerg semi nonparametr regress general linear mix model extend account addit predictor howev avail fit method fail high dimension set mani explanatori variabl present extend concept boost general addit mix model present appropri algorithm use two differ approach fit procedur varianc compon random effectsmethod main tool develop likelihoodbas componentwis boost enforc variabl select general addit mix model contrast common procedur can use highdimension set mani covari avail form influenc unknown complex result estim determin inform criteria perform method investig simul studi binari poisson respons comparison altern approach appli clinic real world dataresult simul show propos method consider stabl accur estim regress function convent approach especi larg number predictor avail method also produc reason result applic real data set illustr multicent aid cohort studyconclus boost algorithm allow extract relev predictor general addit mix model work highdimension set stabl

Resumos Similares

J. Comput. Biol. - An optimization-based sampling scheme for phylogenetic trees. ( 0,797188827731165 )
Res Synth Methods - Semiparametric hazard function estimation in meta-analysis for time to event data. ( 0,770283718648587 )
Med Decis Making - Underestimation of uncertainties in health utilities derived from mapping algorithms involving health-related quality-of-life measures: statistical explanations and potential remedies. ( 0,745633358788534 )
Lifetime Data Anal - Predictive comparison of joint longitudinal-survival modeling: a case study illustrating competing approaches. ( 0,745309575506566 )
Lifetime Data Anal - A proportional hazards regression model with change-points in the baseline function. ( 0,718490798433233 )
J Chem Inf Model - A robust boosting regression tree with applications in quantitative structure-activity relationship studies of organic compounds. ( 0,717093323345241 )
Comput Methods Programs Biomed - mmm: an R package for analyzing multivariate longitudinal data with multivariate marginal models. ( 0,717030709449927 )
Lifetime Data Anal - Regression analysis for cumulative incidence probability under competing risks and left-truncated sampling. ( 0,707667078490897 )
Lifetime Data Anal - Comparison of stopped Cox regression with direct methods such as pseudo-values and binomial regression. ( 0,706251963462989 )
Neural Comput - Least squares estimation without priors or supervision. ( 0,702934928148802 )
Comput Math Methods Med - Application of seemingly unrelated regression in medical data with intermittently observed time-dependent covariates. ( 0,702072472881555 )
Neural Comput - ParceLiNGAM: a causal ordering method robust against latent confounders. ( 0,701819012170637 )
Neural Comput - Reliability of information-based integration of EEG and fMRI data: a simulation study. ( 0,700936374092766 )
Lifetime Data Anal - On estimation of linear transformation models with nested case-control sampling. ( 0,698803120138031 )
Lifetime Data Anal - Semiparametric additive marginal regression models for multiple type recurrent events. ( 0,698149696263145 )
Comput Math Methods Med - Gray's time-varying coefficients model for posttransplant survival of pediatric liver transplant recipients with a diagnosis of cancer. ( 0,698011822494665 )
Lifetime Data Anal - Estimation of odds of concordance based on the Aalen additive model. ( 0,697154098695437 )
Lifetime Data Anal - Pseudo-observations for competing risks with covariate dependent censoring. ( 0,696765563284204 )
Lifetime Data Anal - A flexible semiparametric transformation model for recurrent event data. ( 0,696406180011998 )
Lifetime Data Anal - Regression analysis based on conditional likelihood approach under semi-competing risks data. ( 0,694147712836499 )
Lifetime Data Anal - A generalization of Turnbull's estimator for nonparametric estimation of the conditional survival function with interval-censored data. ( 0,693529856886748 )
Lifetime Data Anal - A two-stage estimation in the Clayton-Oakes model with marginal linear transformation models for multivariate failure time data. ( 0,693348672392514 )
Lifetime Data Anal - A pool-adjacent-violators type algorithm for non-parametric estimation of current status data with dependent censoring. ( 0,693012801578844 )
Comput Math Methods Med - Causal information approach to partial conditioning in multivariate data sets. ( 0,691746226951242 )
Lifetime Data Anal - A hierarchical frailty model applied to two-generation melanoma data. ( 0,691653476908051 )
J Integr Bioinform - ExPlanes: exploring planes in triplet data. ( 0,689781748482812 )
J. Comput. Biol. - Accuracy estimation and parameter advising for protein multiple sequence alignment. ( 0,689324887758437 )
Lifetime Data Anal - Profile local linear estimation of generalized semiparametric regression model for longitudinal data. ( 0,687973321199073 )
Med Decis Making - Calculating Utility Decrements Associated With an Adverse Event: Marginal Tobit and CLAD Coefficients Should Be Used With Caution. ( 0,687217596525891 )
Lifetime Data Anal - The beta modified Weibull distribution. ( 0,686890744154292 )
Lifetime Data Anal - Nonparametric estimation of the cumulative intensities in an interval censored competing risks model. ( 0,686800073955551 )
Comput Methods Programs Biomed - Flexible multivariate marginal models for analyzing multivariate longitudinal data, with applications in R. ( 0,685159370640389 )
Lifetime Data Anal - Proportional hazards regression with interval censored data using an inverse probability weight. ( 0,684638390847982 )
Med Decis Making - Regression estimators for generic health-related quality of life and quality-adjusted life years. ( 0,683412793988089 )
Lifetime Data Anal - Marginal semiparametric multivariate accelerated failure time model with generalized estimating equations. ( 0,682995330543925 )
Lifetime Data Anal - Local linear estimation of concordance probability with application to covariate effects models on association for bivariate failure-time data. ( 0,682873030364704 )
J Chem Inf Model - Estimation of environment-related properties of chemicals for design of sustainable processes: development of group-contribution+ (GC+) property models and uncertainty analysis. ( 0,682653512718077 )
Med Decis Making - Generalized additive models for the analysis of EQ-5D utility data. ( 0,680568906526903 )
Lifetime Data Anal - Estimating treatment effects on the marginal recurrent event mean in the presence of a terminating event. ( 0,680353863391199 )
Lifetime Data Anal - Nonparametric quasi-likelihood for right censored data. ( 0,679594598501136 )
Med Biol Eng Comput - Non-invasive continuous glucose monitoring: improved accuracy of point and trend estimates of the Multisensor system. ( 0,678613316804877 )
Lifetime Data Anal - Imputation for semiparametric transformation models with biased-sampling data. ( 0,677382818991722 )
Comput Methods Programs Biomed - A simulation procedure based on copulas to generate clustered multi-state survival data. ( 0,677189032277131 )
Lifetime Data Anal - Cox regression for mixed case interval-censored data with covariate errors. ( 0,676623793411795 )
Neural Comput - A Monte Carlo Metropolis-Hastings algorithm for sampling from distributions with intractable normalizing constants. ( 0,673613709510019 )
Res Synth Methods - Robust variance estimation in meta-regression with dependent effect size estimates. ( 0,672815707179461 )
Neural Comput - Self-consistent learning of the environment. ( 0,672342970211449 )
Comput Methods Programs Biomed - Bayesian Decision Trees for predicting survival of patients: a study on the US National Trauma Data Bank. ( 0,670220124556102 )
Res Synth Methods - Combining study outcome measures using dominance adjusted weights. ( 0,669784525270687 )
Res Synth Methods - Comparison of statistical inferences from the DerSimonian-Laird and alternative random-effects model meta-analyses - an empirical assessment of 920 Cochrane primary outcome meta-analyses. ( 0,669557376393875 )
Neural Comput - On quadrature methods for refractory point process likelihoods. ( 0,668531678310484 )
Lifetime Data Anal - Estimation of treatment effects based on possibly misspecified Cox regression. ( 0,667986269445485 )
Brief. Bioinformatics - On the validity of time-dependent AUC estimators. ( 0,666663556162104 )
IEEE Trans Pattern Anal Mach Intell - Learning Graphical Model Parameters with Approximate Marginal Inference. ( 0,664663470073444 )
Med Decis Making - Eliciting benefit-risk preferences and probability-weighted utility using choice-format conjoint analysis. ( 0,663300084784266 )
Comput Methods Programs Biomed - The input-output relationship approach to structural identifiability analysis. ( 0,661808323301654 )
Lifetime Data Anal - Robust methods to improve efficiency and reduce bias in estimating survival curves in randomized clinical trials. ( 0,661232884338741 )
Lifetime Data Anal - An introduction to survival models: in honor of Ross Prentice. ( 0,661120048872422 )
Lifetime Data Anal - Likelihood ratio procedures and tests of fit in parametric and semiparametric copula models with censored data. ( 0,660427971640161 )
IEEE Trans Image Process - Nonlinearity detection in hyperspectral images using a polynomial post-nonlinear mixing model. ( 0,660280734091355 )
Med Decis Making - Adjusting survival time estimates to account for treatment switching in randomized controlled trials--an economic evaluation context: methods, limitations, and recommendations. ( 0,65998155757483 )
Comput Methods Programs Biomed - A warning concerning the estimation of multinomial logistic models with correlated responses in SAS. ( 0,659275419692232 )
Lifetime Data Anal - Simultaneous marginal survival estimators when doubly censored data is present. ( 0,657926144214063 )
Neural Comput - Firing variability is higher than deduced from the empirical coefficient of variation. ( 0,657287488423836 )
Lifetime Data Anal - Events per variable for risk differences and relative risks using pseudo-observations. ( 0,656782600765032 )
Lifetime Data Anal - Semiparametric methods for center effect measures based on the ratio of survival functions. ( 0,656565969105404 )
Lifetime Data Anal - Parametric survival densities from phase-type models. ( 0,655085301371733 )
Lifetime Data Anal - Nonparametric estimation of current status data with dependent censoring. ( 0,654215243868626 )
Lifetime Data Anal - Robust inference in discrete hazard models for randomized clinical trials. ( 0,653961880800881 )
J. Comput. Biol. - Improved harmonic mean estimator for phylogenetic model evidence. ( 0,652836596351094 )
Lifetime Data Anal - Quantifying the average of the time-varying hazard ratio via a class of transformations. ( 0,651143300266472 )
Med Decis Making - Evidence synthesis for decision making 2: a generalized linear modeling framework for pairwise and network meta-analysis of randomized controlled trials. ( 0,650002830354273 )
Methods Inf Med - Informative simultaneous confidence intervals in hierarchical testing. ( 0,649978140755281 )
IEEE Trans Image Process - On the method of logarithmic cumulants for parametric probability density function estimation. ( 0,648920994596711 )
Lifetime Data Anal - Semiparametric analysis of recurrent events: artificial censoring, truncation, pairwise estimation and inference. ( 0,648573263390315 )
Lifetime Data Anal - Analysis of recurrent events with non-negligible event duration, with application to assessing hospital utilization. ( 0,648444642018026 )
IEEE Trans Pattern Anal Mach Intell - Covariate Shift Adaptation for Discriminative 3D Pose Estimation. ( 0,646795800520833 )
Lifetime Data Anal - An additive-multiplicative rates model for recurrent event data with informative terminal event. ( 0,646361885003139 )
IEEE Trans Image Process - The sparse matrix transform for covariance estimation and analysis of high dimensional signals. ( 0,644822140863463 )
Lifetime Data Anal - Nonparametric estimation with recurrent competing risks data. ( 0,644336508789171 )
Lifetime Data Anal - Computationally simple estimation and improved efficiency for special cases of double truncation. ( 0,643985499738671 )
Comput Methods Programs Biomed - Model based period analysis of absolute and relative survival with R: data preparation, model fitting and derivation of survival estimates. ( 0,643059109228663 )
Spat Spatiotemporal Epidemiol - The use of sampling weights in Bayesian hierarchical models for small area estimation. ( 0,642354528129954 )
IEEE Trans Pattern Anal Mach Intell - Maximum Likelihood Estimation of Depth Maps Using Photometric Stereo. ( 0,642254485412867 )
Lifetime Data Anal - Statistical inference based on the nonparametric maximum likelihood estimator under double-truncation. ( 0,641729595054237 )
Comput Methods Programs Biomed - ORTH: R and SAS software for regression models of correlated binary data based on orthogonalized residuals and alternating logistic regressions. ( 0,637660247437603 )
IEEE Trans Image Process - Maximum likelihood orientation estimation of 1-D patterns in Laguerre-Gauss subspaces. ( 0,636231780523566 )
Lifetime Data Anal - Marginal hazard regression for correlated failure time data with auxiliary covariates. ( 0,635428569059979 )
Lifetime Data Anal - Additive-multiplicative rates model for recurrent events. ( 0,635160606517791 )
Comput. Biol. Med. - Density-based Monte Carlo filter and its applications in nonlinear stochastic differential equation models. ( 0,635123289917336 )
Int J Neural Syst - A generalized Leaky Integrate-and-Fire neuron model with fast implementation method. ( 0,63504174014381 )
Lifetime Data Anal - On computing standard errors for marginal structural Cox models. ( 0,634371648896566 )
Lifetime Data Anal - Linear regression analysis of survival data with missing censoring indicators. ( 0,633849989447627 )
Lifetime Data Anal - Estimation in a competing risks proportional hazards model under length-biased sampling with censoring. ( 0,633703513875354 )
Comput Methods Programs Biomed - Mixture and non-mixture cure fraction models based on the generalized modified Weibull distribution with an application to gastric cancer data. ( 0,633199841992851 )
Lifetime Data Anal - Estimation of cumulative incidence functions when the lifetime distributions are uniformly stochastically ordered. ( 0,632131479915185 )
Lifetime Data Anal - A functional inference for multivariate current status data with mismeasured covariate. ( 0,632063943137378 )
Comput Methods Programs Biomed - A Bayesian multilevel model for fMRI data analysis. ( 0,629879573384836 )
Lifetime Data Anal - A general joint model for longitudinal measurements and competing risks survival data with heterogeneous random effects. ( 0,628942084133813 )
Lifetime Data Anal - A copula model for marked point processes. ( 0,627805846726381 )