Methods Inf Med - Efficiency evaluation of autonomic heart control by using the principal component analysis of ECG P-wave.

Tópicos

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Resumo

CKGROUND: Cardiac output is controlled by the autonomic nervous system by changing the heart rate and/or the contractions of the heart muscle in response to the hemodynamic needs of the whole body. Malfunction of these mechanisms causes the postural orthostatic tachycardia syndrome and/or the chronic fatigue syndrome. Evaluation of functionality and efficiency of the control mechanisms could give valuable diagnostic information in the early stages of dysfunction of the heart control systems and help to monitor the healing process in rehabilitation period after interventions.OBJECTIVES: In this study we demonstrate how P-wave changes evoked by an orthostatic test could be quantitatively evaluated by using the method based on the principal component analysis.METHODS: ECG signals were recorded during an orthostatic test performed according to the typical protocol in three groups of volunteer subjects representing healthy young and older persons, part of which had transient periods of supraventricular arrhythmias. Quantitative evaluation of P-wave morphology changes was performed by means of principal component analysis-based method.RESULTS: Principal component-based estimates showed certain variety of P-wave shape during orthostatic test, what revealed a possibility to evaluate the properties of parasympathetic heart control.CONCLUSIONS: Quantitative evaluation of ECG P-wave changes evoked by an orthostatic test by using a newly developed method provides a quantitative estimate for functionality and efficiency of the heart rate control mechanisms. The method could be used in eHealth systems.

Resumo Limpo

ckground cardiac output control autonom nervous system chang heart rate andor contract heart muscl respons hemodynam need whole bodi malfunct mechan caus postur orthostat tachycardia syndrom andor chronic fatigu syndrom evalu function effici control mechan give valuabl diagnost inform earli stage dysfunct heart control system help monitor heal process rehabilit period interventionsobject studi demonstr pwave chang evok orthostat test quantit evalu use method base princip compon analysismethod ecg signal record orthostat test perform accord typic protocol three group volunt subject repres healthi young older person part transient period supraventricular arrhythmia quantit evalu pwave morpholog chang perform mean princip compon analysisbas methodresult princip componentbas estim show certain varieti pwave shape orthostat test reveal possibl evalu properti parasympathet heart controlconclus quantit evalu ecg pwave chang evok orthostat test use newli develop method provid quantit estim function effici heart rate control mechan method use ehealth system

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