Methods Inf Med - Surface and intramural reentrant patterns during atrial fibrillation in the sheep.

Tópicos

{ activ(1138) subject(705) human(624) }
{ analysi(2126) use(1163) compon(1037) }
{ general(901) number(790) one(736) }
{ bind(1733) structur(1185) ligand(1036) }
{ signal(2180) analysi(812) frequenc(800) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ model(2220) cell(1177) simul(1124) }
{ howev(809) still(633) remain(590) }
{ risk(3053) factor(974) diseas(938) }
{ research(1085) discuss(1038) issu(1018) }
{ model(2341) predict(2261) use(1141) }
{ estim(2440) model(1874) function(577) }
{ system(1976) rule(880) can(841) }
{ imag(2830) propos(1344) filter(1198) }
{ motion(1329) object(1292) video(1091) }
{ assess(1506) score(1403) qualiti(1306) }
{ chang(1828) time(1643) increas(1301) }
{ concept(1167) ontolog(924) domain(897) }
{ control(1307) perform(991) simul(935) }
{ use(2086) technolog(871) perceiv(783) }
{ result(1111) use(1088) new(759) }
{ method(1219) similar(1157) match(930) }
{ framework(1458) process(801) describ(734) }
{ learn(2355) train(1041) set(1003) }
{ design(1359) user(1324) use(1319) }
{ import(1318) role(1303) understand(862) }
{ perform(1367) use(1326) method(1137) }
{ monitor(1329) mobil(1314) devic(1160) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ time(1939) patient(1703) rate(768) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ cancer(2502) breast(956) screen(824) }
{ decis(3086) make(1611) patient(1517) }
{ model(3404) distribut(989) bayesian(671) }
{ can(774) often(719) complex(702) }
{ imag(1947) propos(1133) code(1026) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ sequenc(1873) structur(1644) protein(1328) }
{ featur(3375) classif(2383) classifi(1994) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ studi(2440) review(1878) systemat(933) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ data(1714) softwar(1251) tool(1186) }
{ care(1570) inform(1187) nurs(1089) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ perform(999) metric(946) measur(919) }
{ system(1050) medic(1026) inform(1018) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ studi(1119) effect(1106) posit(819) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ patient(1821) servic(1111) care(1106) }
{ can(981) present(881) function(850) }
{ high(1669) rate(1365) level(1280) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ implement(1333) system(1263) develop(1122) }
{ survey(1388) particip(1329) question(1065) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

TRODUCTION: This article is part of the Focus Theme of Methods of Information in Medicine on "Biosignal Interpretation: Advanced Methods for Studying Cardiovascular and Respiratory Systems".BACKGROUND: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in humans and is predicted to dramatically increase its prevalence in the future. High-resolution mapping data and Fourier power spectral analysis with its dominant frequency support the hypothesis that AF in the structurally normal sheep heart and in some patients often presents organized drivers in the form of periodic surface re-entries or breakthroughs. Nevertheless, the dynamics of those surface patterns of activity, as well as their intramural components are still poorly understood.OBJECTIVE: To present data on AF waves from the surface of isolated sheep hearts and discuss the interpretation of their intramural patterns.METHODS: We used a combination of endocardial-epicardial optical mapping with phase and spectral analysis as well as computer simulation of the re-entrant activity in the myocardial wall.RESULTS: Analysis of the surfaces' optical mapping data in the phase domain reveals that activation of the posterior left atrium (PLA) consisted of alternating patterns of breakthroughs and reentries. The patterns on the endocardial and epicardial PLA surface at any given moment of time of the AF could be either identical or not identical, and the activity in the thickness of the PLA wall is hypothesized to conform to either ectopic discharge or reentrant scroll waves, but a definite evidence for the presence of such mechanisms is currently lacking. A universal minimal-principle theory is shown in a computer model to result in a tendency of the axis of the scroll waves to align with the myocardial fibers inside the wall.CONCLUSION: The tendency of filaments of scroll waves to align with myocardial fibers may contribute to the variety and intermittency of surface rotors seen in AF.

Resumo Limpo

troduct articl part focus theme method inform medicin biosign interpret advanc method studi cardiovascular respiratori systemsbackground atrial fibril af common sustain cardiac arrhythmia human predict dramat increas preval futur highresolut map data fourier power spectral analysi domin frequenc support hypothesi af structur normal sheep heart patient often present organ driver form period surfac reentri breakthrough nevertheless dynam surfac pattern activ well intramur compon still poor understoodobject present data af wave surfac isol sheep heart discuss interpret intramur patternsmethod use combin endocardialepicardi optic map phase spectral analysi well comput simul reentrant activ myocardi wallresult analysi surfac optic map data phase domain reveal activ posterior left atrium pla consist altern pattern breakthrough reentri pattern endocardi epicardi pla surfac given moment time af either ident ident activ thick pla wall hypothes conform either ectop discharg reentrant scroll wave definit evid presenc mechan current lack univers minimalprincipl theori shown comput model result tendenc axi scroll wave align myocardi fiber insid wallconclus tendenc filament scroll wave align myocardi fiber may contribut varieti intermitt surfac rotor seen af

Resumos Similares

Med Biol Eng Comput - Safety of multi-channel stimulation implants: a single blocking capacitor per channel is not sufficient after single-fault failure. ( 0,713335233872287 )
Med Biol Eng Comput - Transmembrane potential generated by a magnetically induced transverse electric field in a cylindrical axonal model. ( 0,662860885017975 )
Med Biol Eng Comput - On the reliability of frequency components in systolic arterial pressure in patients with atrial fibrillation. ( 0,637079566672382 )
Med Biol Eng Comput - Measuring skin conductance over clothes. ( 0,636333721433634 )
Comput. Biol. Med. - Evaluation of different stimulation and measurement patterns based on internal electrode: application in cardiac impedance tomography. ( 0,635974098550639 )
Med Biol Eng Comput - Sensorimotor cortical response during motion reflecting audiovisual stimulation: evidence from fractal EEG analysis. ( 0,631326591642223 )
Comput Math Methods Med - The strength-interval curve in cardiac tissue. ( 0,630924531162968 )
Med Biol Eng Comput - Spinal cord direct current stimulation: finite element analysis of the electric field and current density. ( 0,626194883666745 )
J Clin Monit Comput - Muscle relaxant use during intraoperative neurophysiologic monitoring. ( 0,625157676582052 )
Comput. Biol. Med. - Simulation of the microscopic process during initiation of stent thrombosis. ( 0,624009166555342 )
J Clin Monit Comput - Quantification of the proportion of motor neurons recruited by transcranial electrical stimulation during intraoperative motor evoked potential monitoring. ( 0,623541390330747 )
Comput Methods Programs Biomed - Development/global validation of a 6-month-old pediatric head finite element model and application in investigation of drop-induced infant head injury. ( 0,622352486188446 )
Int J Comput Assist Radiol Surg - fMRI assessment of upper extremity related brain activation with an MRI-compatible manipulandum. ( 0,619333607882761 )
Med Biol Eng Comput - Brain hypothermia induced by cold spinal fluid using a torso cooling pad: theoretical analyses. ( 0,615702492786856 )
Comput. Aided Surg. - A biomechanical study regarding the effect of tissue harvesting from the thorax on its movement during inspiration. ( 0,614274106796993 )
J Clin Monit Comput - Augmentation of motor evoked potentials using multi-train transcranial electrical stimulation in intraoperative neurophysiologic monitoring during spinal surgery. ( 0,61278321016312 )
Comput Methods Programs Biomed - Matlab-based interface for the simultaneous acquisition of force measures and Doppler ultrasound muscular images. ( 0,607578817714059 )
Med Biol Eng Comput - Effects of muscle fibre shortening on the characteristics of surface motor unit potentials. ( 0,606376757464664 )
Artif Intell Med - Brain-computer interface analysis of a dynamic visuo-motor task. ( 0,605394523784562 )
Comput Math Methods Med - Noninvasive measurement of conductivity anisotropy at larmor frequency using MRI. ( 0,603703531043279 )
Methods Inf Med - Slow adaptation of ventricular repolarization as a cause of arrhythmia? ( 0,602220263398675 )
Comput. Biol. Med. - Simulating a dual-array electrode configuration to investigate the influence of skeletal muscle fatigue following functional electrical stimulation. ( 0,600992355043829 )
J Chem Inf Model - Engineering antimicrobial peptides with improved antimicrobial and hemolytic activities. ( 0,600751576421679 )
Comput Methods Programs Biomed - Performance optimization of current focusing and virtual electrode strategies in retinal implants. ( 0,60025871363042 )
Med Biol Eng Comput - Estimating nerve excitation thresholds to cutaneous electrical stimulation by finite element modeling combined with a stochastic branching nerve fiber model. ( 0,600058691186681 )
Med Biol Eng Comput - Where does transcranial magnetic stimulation (TMS) stimulate? Modelling of induced field maps for some common cortical and cerebellar targets. ( 0,599938026132149 )
Comput. Biol. Med. - Field distribution of epidural electrical stimulation. ( 0,598142480628803 )
Med Biol Eng Comput - Sensory data fusion of pressure mattress and wireless inertial magnetic measurement units. ( 0,596772552604202 )
Comput. Biol. Med. - Muscle activity detection in electromyograms recorded during periodic movements. ( 0,595423104609431 )
J Chem Inf Model - Molecular dynamics studies of the protein-protein interactions in inhibitor of B kinase-?. ( 0,594303912586776 )
Med Biol Eng Comput - Is it possible to detect dendrite currents using presently available magnetic resonance imaging techniques? ( 0,591870241193189 )
Med Biol Eng Comput - Electrical stimulation for the suppression of pathological tremor. ( 0,588863723391621 )
Int J Neural Syst - Computational modeling of transcranial direct current stimulation in the child brain: implications for the treatment of refractory childhood focal epilepsy. ( 0,587756295461145 )
Comput Math Methods Med - Application of computational lower extremity model to investigate different muscle activities and joint force patterns in knee osteoarthritis patients during walking. ( 0,586489579307134 )
Med Biol Eng Comput - Advanced biofeedback from surface electromyography signals using fuzzy system. ( 0,585793327600359 )
Med Biol Eng Comput - The influence of skeletal muscle anisotropy on electroporation: in vivo study and numerical modeling. ( 0,584003918210428 )
IEEE Trans Vis Comput Graph - Visualization and Analysis of Vortex-Turbine Intersections in Wind Farms. ( 0,583633588958073 )
Comput Math Methods Med - Neuroelectrical correlates of trustworthiness and dominance judgments related to the observation of political candidates. ( 0,582412222078618 )
Methods Inf Med - Efficiency evaluation of autonomic heart control by using the principal component analysis of ECG P-wave. ( 0,581252960371051 )
Med Biol Eng Comput - Comparison of spinal cord stimulation profiles from intra- and extradural electrode arrangements by finite element modelling. ( 0,580741293241293 )
Neural Comput - Discriminative learning of propagation and spatial pattern for motor imagery EEG analysis. ( 0,575861924863642 )
Med Biol Eng Comput - Axial head rotation increases facet joint capsular ligament strains in automotive rear impact. ( 0,574732766452451 )
Med Biol Eng Comput - Conduction block of whole nerve without onset firing using combined high frequency and direct current. ( 0,574041112795676 )
Med Biol Eng Comput - A method for determination of muscle fiber diameter using single fiber potential (SFP) analysis. ( 0,572546900667358 )
Med Biol Eng Comput - System identification of evoked mechanomyogram from abductor pollicis brevis muscle in isometric contraction. ( 0,572134108383459 )
J Chem Inf Model - Automation of the CHARMM General Force Field (CGenFF) I: bond perception and atom typing. ( 0,571897092822696 )
Med Biol Eng Comput - The movement of a nerve in a magnetic field: application to MRI Lorentz effect imaging. ( 0,570900297808532 )
Med Biol Eng Comput - Towards the development of a novel experimental shoulder simulator with rotating scapula and individually controlled muscle forces simulating the rotator cuff. ( 0,570311496362633 )
Comput. Biol. Med. - Empirical modeling of renal motion for improved targeting during focused ultrasound surgery. ( 0,570082049810988 )
Int J Neural Syst - The effect of high and low frequency cortical stimulation with a fixed or a poisson distributed interpulse interval on cortical excitability in rats. ( 0,56939862337373 )
Med Biol Eng Comput - Protegemed2: an extended platform based on RFID to identify EME and improve the detection of microshocks. ( 0,568392914098745 )
Comput Methods Programs Biomed - A passive movement method for parameter estimation of a musculo-skeletal arm model incorporating a modified hill muscle model. ( 0,567507530263011 )
Comput Biol Chem - miRNA and tropism of human parvovirus B19. ( 0,567187912123993 )
Med Biol Eng Comput - The effect of local anatomy on the electric field induced by TMS: evaluation at 14 different target sites. ( 0,565513568309934 )
IEEE J Biomed Health Inform - Inverse estimation of multiple muscle activations from joint moment with muscle synergy extraction. ( 0,564366418270758 )
Comput Biol Chem - Multiscale modelling to understand the self-assembly mechanism of human ?2-adrenergic receptor in lipid bilayer. ( 0,563822952034484 )
IEEE J Biomed Health Inform - Accelerometry-based home monitoring for detection of nocturnal hypermotor seizures based on novelty detection. ( 0,560944627603509 )
Comput Methods Programs Biomed - Independent complexity patterns in single neuron activity induced by static magnetic field. ( 0,560333088392059 )
J Clin Monit Comput - Assessment and confirmation of tracheal intubation when capnography fails: a novel use for an USB camera. ( 0,560208326564786 )
Comput. Biol. Med. - Estimation of saline-mixed tissue conductivity and ablation lesion size. ( 0,559853595088466 )
Int J Neural Syst - Transcranial magnetic stimulation (TMS) modulates epileptiform discharges in patients with frontal lobe epilepsy: a preliminary EEG-TMS study. ( 0,558020027503035 )
J Chem Inf Model - Molecular dynamics simulations for human CAR inverse agonists. ( 0,557115225972998 )
Comput Math Methods Med - Human atrial cell models to analyse haemodialysis-related effects on cardiac electrophysiology: work in progress. ( 0,556654581547274 )
Comput. Biol. Med. - Effects of degenerated intervertebral discs on intersegmental rotations, intradiscal pressures, and facet joint forces of the whole lumbar spine. ( 0,556563309786535 )
Int J Neural Syst - Electrophysiological responses from vagus nerve stimulation in rats. ( 0,556023698994211 )
J Clin Monit Comput - Spinal cord injury from electrocautery: observations in a porcine model using electromyography and motor evoked potentials. ( 0,552254102807167 )
Med Biol Eng Comput - Deformation and pressure propagation in deep tissue during mechanical painful pressure stimulation. ( 0,55206416970148 )
Med Biol Eng Comput - Optimal chest compression in cardiopulmonary resuscitation depends upon thoracic and back support stiffness. ( 0,550643601205717 )
Neural Comput - Intracellular dynamics of virtual place cells. ( 0,548647535413159 )
Comput Methods Programs Biomed - Effects of virtual environment platforms on emotional responses. ( 0,547508817669444 )
Med Biol Eng Comput - Energy harvesting through arterial wall deformation: design considerations for a magneto-hydrodynamic generator. ( 0,545238344519233 )
Comput. Biol. Med. - Classification algorithms for the identification of structural injury in TBI using brain electrical activity. ( 0,544159702842981 )
Med Biol Eng Comput - Synthesis of optimal electrical stimulation patterns for functional motion restoration: applied to spinal cord-injured patients. ( 0,542711793257827 )
Med Biol Eng Comput - Peculiarities of extracellular potentials produced by deep muscles. Part 1: single fibre potential fields. ( 0,540841099508784 )
Comput Methods Programs Biomed - Direct effects of audio-visual stimulation on EEG. ( 0,539990836180812 )
Methods Inf Med - Quantifying changes in EEG complexity induced by photic stimulation. ( 0,538439947581548 )
J Chem Inf Model - Interactions between voltage sensor and pore domains in a hERG K+ channel model from molecular simulations and the effects of a voltage sensor mutation. ( 0,537909217328886 )
Comput Methods Programs Biomed - Analysis of normal and epileptic seizure EEG signals using empirical mode decomposition. ( 0,536550880341611 )
J Clin Monit Comput - Increases in voltage may produce false-negatives when using transcranial motor evoked potentials to detect an isolated nerve root injury. ( 0,535952539049378 )
Comput Math Methods Med - Trial-by-trial adaptation of movements during mental practice under force field. ( 0,535038732429945 )
Neural Comput - A detailed and fast model of extracellular recordings. ( 0,534709757490575 )
J Chem Inf Model - Molecular mechanism-based network-like similarity graphs reveal relationships between different types of receptor ligands and structural changes that determine agonistic, inverse-agonistic, and antagonistic effects. ( 0,534354588870256 )
J Chem Inf Model - Antiviral atropisomers: conformational energy surfaces by NMR for host-directed myxovirus blockers. ( 0,533650129248887 )
Comput Methods Programs Biomed - Simulation of surface EMG for the analysis of muscle activity during whole body vibratory stimulation. ( 0,531736122403656 )
Comput Methods Programs Biomed - Hierarchical pose estimation for human gait analysis. ( 0,530727667701091 )
Comput Math Methods Med - Epitope mapping of metuximab on CD147 using phage display and molecular docking. ( 0,530202624739983 )
IEEE J Biomed Health Inform - A physiological time series dynamics-based approach to patient monitoring and outcome prediction. ( 0,529899990718097 )
Med Biol Eng Comput - The inverse problem of bioelectricity: an evaluation. ( 0,529545389470588 )
J Med Syst - The effect of an auxiliary stimulation on motor function restoration by FES. ( 0,529202142232869 )
IEEE J Biomed Health Inform - BreathSens: A Continuous On-Bed Respiratory Monitoring System With Torso Localization Using an Unobtrusive Pressure Sensing Array. ( 0,527909886533065 )
Comput Math Methods Med - Modiolus-hugging intracochlear electrode array with shape memory alloy. ( 0,527093790445261 )
Med Biol Eng Comput - The analysis of forces needed for the suturing of elliptical skin wounds. ( 0,526239771903455 )
Med Biol Eng Comput - Discrimination of left and right leg motor imagery for brain-computer interfaces. ( 0,525584005044037 )
Comput Math Methods Med - Independent component analysis of instantaneous power-based fMRI. ( 0,523899244193426 )
J Chem Inf Model - Molecular dynamics simulations of the adenosine A2a receptor in POPC and POPE lipid bilayers: effects of membrane on protein behavior. ( 0,5222364358143 )
J Chem Inf Model - Calculations of the free energy of interaction of the c-Fos-c-Jun coiled coil: effects of the solvation model and the inclusion of polarization effects. ( 0,522211991345975 )
Comput Math Methods Med - Spreading out muscle mass within a Hill-type model: a computer simulation study. ( 0,521745624434429 )
Comput Math Methods Med - Numerical simulations of MREIT conductivity imaging for brain tumor detection. ( 0,521576772507706 )
Res Synth Methods - Structural Approach to Bias in Meta-analyses. ( 0,519807907617236 )
IEEE J Biomed Health Inform - Robust automatic measurement of 3D scanned models for the human body fat estimation. ( 0,519564307879579 )