Neural Comput - A calcium-based simple model of multiple spike interactions in spike-timing-dependent plasticity.

Tópicos

{ model(3480) simul(1196) paramet(876) }
{ network(2748) neural(1063) input(814) }
{ first(2504) two(1366) second(1323) }
{ concept(1167) ontolog(924) domain(897) }
{ sequenc(1873) structur(1644) protein(1328) }
{ featur(3375) classif(2383) classifi(1994) }
{ model(2220) cell(1177) simul(1124) }
{ research(1085) discuss(1038) issu(1018) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ use(976) code(926) identifi(902) }
{ bind(1733) structur(1185) ligand(1036) }
{ take(945) account(800) differ(722) }
{ assess(1506) score(1403) qualiti(1306) }
{ algorithm(1844) comput(1787) effici(935) }
{ general(901) number(790) one(736) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ system(1050) medic(1026) inform(1018) }
{ perform(1367) use(1326) method(1137) }
{ spatial(1525) area(1432) region(1030) }
{ group(2977) signific(1463) compar(1072) }
{ use(1733) differ(960) four(931) }
{ result(1111) use(1088) new(759) }
{ estim(2440) model(1874) function(577) }
{ method(2212) result(1239) propos(1039) }
{ model(3404) distribut(989) bayesian(671) }
{ can(774) often(719) complex(702) }
{ imag(1947) propos(1133) code(1026) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ imag(1057) registr(996) error(939) }
{ method(1219) similar(1157) match(930) }
{ imag(2830) propos(1344) filter(1198) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ studi(2440) review(1878) systemat(933) }
{ motion(1329) object(1292) video(1091) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ learn(2355) train(1041) set(1003) }
{ clinic(1479) use(1117) guidelin(835) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ data(1714) softwar(1251) tool(1186) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ care(1570) inform(1187) nurs(1089) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ howev(809) still(633) remain(590) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ import(1318) role(1303) understand(862) }
{ compound(1573) activ(1297) structur(1058) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ data(3008) multipl(1320) sourc(1022) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ drug(1928) target(777) effect(648) }
{ implement(1333) system(1263) develop(1122) }
{ survey(1388) particip(1329) question(1065) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ method(1969) cluster(1462) data(1082) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Spike-timing-dependent plasticity (STDP) is a form of synaptic modification that depends on the relative timings of presynaptic and postsynaptic spikes. In this letter, we proposed a calcium-based simple STDP model, described by an ordinary differential equation having only three state variables: one represents the density of intracellular calcium, one represents a fraction of open state NMDARs, and one represents the synaptic weight. We shown that in spite of its simplicity, the model can reproduce the properties of the plasticity that have been experimentally measured in various brain areas (e.g., layer 2/3 and 5 visual cortical slices, hippocampal cultures, and layer 2/3 somatosensory cortical slices) with respect to various patterns of presynaptic and postsynaptic spikes. In addition, comparisons with other STDP models are made, and the significance and advantages of the proposed model are discussed.

Resumo Limpo

spiketimingdepend plastic stdp form synapt modif depend relat time presynapt postsynapt spike letter propos calciumbas simpl stdp model describ ordinari differenti equat three state variabl one repres densiti intracellular calcium one repres fraction open state nmdar one repres synapt weight shown spite simplic model can reproduc properti plastic experiment measur various brain area eg layer visual cortic slice hippocamp cultur layer somatosensori cortic slice respect various pattern presynapt postsynapt spike addit comparison stdp model made signific advantag propos model discuss

Resumos Similares

Neural Comput - On the performance of voltage stepping for the simulation of adaptive, nonlinear integrate-and-fire neuronal networks. ( 0,755751019404226 )
Neural Comput - Analytical integrate-and-fire neuron models with conductance-based dynamics and realistic postsynaptic potential time course for event-driven simulation strategies. ( 0,744632360239854 )
Neural Comput - Projective clustering using neural networks with adaptive delay and signal transmission loss. ( 0,708517548377468 )
Neural Comput - Theoretical and evolutionary parameter tuning of neural oscillators with a double-chain structure for generating rhythmic signals. ( 0,699002137767824 )
J Clin Monit Comput - The standard strong ion difference, standard total titratable base, and their relationship to the Boston compensation rules and the Van Slyke equation for extracellular fluid. ( 0,68817237179884 )
Neural Comput - Computing confidence intervals for point process models. ( 0,684212042576844 )
Neural Comput - A systematic method for configuring VLSI networks of spiking neurons. ( 0,682896639367636 )
Comput Math Methods Med - Global hopf bifurcation on two-delays leslie-gower predator-prey system with a prey refuge. ( 0,680136040813605 )
Comput Biol Chem - Parameter sensitivity analysis of stochastic models: application to catalytic reaction networks. ( 0,669948631486899 )
Int J Neural Syst - A generalized Leaky Integrate-and-Fire neuron model with fast implementation method. ( 0,666693722394714 )
Brief. Bioinformatics - Choosing appropriate models for protein-protein interaction networks: a comparison study. ( 0,66582458331919 )
Neural Comput - A principled dimension-reduction method for the population density approach to modeling networks of neurons with synaptic dynamics. ( 0,660694360508597 )
Comput Methods Programs Biomed - A model of cerebral cortex formation during fetal development using reaction-diffusion-convection equations with Turing space parameters. ( 0,65873254924026 )
Comput Math Methods Med - ModeLang: a new approach for experts-friendly viral infections modeling. ( 0,656163395793284 )
Comput Methods Programs Biomed - Development of a computer algorithm for feedback controlled electrical nerve fiber stimulation. ( 0,648592062645866 )
Comput Math Methods Med - Synchronization of coupled different chaotic FitzHugh-Nagumo neurons with unknown parameters under communication-direction-dependent coupling. ( 0,64833875193058 )
Neural Comput - Applying the multivariate time-rescaling theorem to neural population models. ( 0,648211907890945 )
Comput Math Methods Med - Theorems and application of local activity of CNN with five state variables and one port. ( 0,647436228108829 )
Neural Comput - Synchronization of stochastic competitive neural networks with different timescales and reaction-diffusion terms. ( 0,645375236797246 )
Int J Neural Syst - Double-layered models can explain macro and micro structure of human sleep. ( 0,644416336906829 )
J Integr Bioinform - An advanced environment for hybrid modeling of biological systems based on modelica. ( 0,641965265153818 )
Comput Math Methods Med - Computational modeling of microabscess formation. ( 0,639809913291595 )
Comput Methods Programs Biomed - Innovative model to simulate exhalation phase in human respiratory system. ( 0,639712093571136 )
Comput. Biol. Med. - Modeling multiple experiments using regularized optimization: A case study on bacterial glucose utilization dynamics. ( 0,63671274928767 )
Neural Comput - Neuronal assembly dynamics in supervised and unsupervised learning scenarios. ( 0,631545572901783 )
Neural Comput - Statistical mechanics of reward-modulated learning in decision-making networks. ( 0,631312045519387 )
Neural Comput - Active data collection for efficient estimation and comparison of nonlinear neural models. ( 0,630964375011393 )
IEEE Trans Neural Netw Learn Syst - Exponential Stabilization of Memristor-based Chaotic Neural Networks with Time-Varying Delays via Intermittent Control. ( 0,628076842018968 )
Comput Math Methods Med - Analytical solutions for the mathematical model describing the formation of liver zones via Adomian's method. ( 0,627324912460669 )
Neural Comput - Computing with a canonical neural circuits model with pool normalization and modulating feedback. ( 0,623696775509191 )
Neural Comput - Exact event-driven implementation for recurrent networks of stochastic perfect integrate-and-fire neurons. ( 0,622802814920816 )
Int J Neural Syst - Dynamics of collective multi-stability in models of multi-unit neuronal systems. ( 0,622705891392368 )
Comput Math Methods Med - Numerical stability of partitioned approach in fluid-structure interaction for a deformable thin-walled vessel. ( 0,621934029994871 )
Comput Methods Programs Biomed - Functionality of the baroreceptor nerves in heart rate regulation. ( 0,620332476737023 )
Comput Math Methods Med - Theoretical Hill-type muscle and stability: numerical model and application. ( 0,61949328472919 )
Neural Comput - A low-order model of biological neural networks. ( 0,619216217531263 )
Neural Comput - Toward unified hybrid simulation techniques for spiking neural networks. ( 0,618281131259524 )
Comput Biol Chem - An efficient nonlinear finite-difference approach in the computational modeling of the dynamics of a nonlinear diffusion-reaction equation in microbial ecology. ( 0,618000340731787 )
IEEE Trans Neural Netw Learn Syst - Stochastic Stability of Delayed Neural Networks With Local Impulsive Effects. ( 0,617213399848368 )
IEEE Trans Neural Netw Learn Syst - Approximate N-Player Nonzero-Sum Game Solution for an Uncertain Continuous Nonlinear System. ( 0,614502433207647 )
Neural Comput - Effect of phase response curve skewness on synchronization of electrically coupled neuronal oscillators. ( 0,614502433207647 )
Neural Comput - Cross-talk induces bifurcations in nonlinear models of synaptic plasticity. ( 0,613471610326828 )
Comput Methods Programs Biomed - System approach to modeling of liver glucose metabolism with physiologically interpreted model parameters outgoing from [18F]FDG concentrations measured by PET. ( 0,612176618421292 )
Med Biol Eng Comput - A fluid-structure interaction model of the aortic valve with coaptation and compliant aortic root. ( 0,611828152914983 )
Comput Biol Chem - A stochastic evolution model for residue Insertion-Deletion Independent from Substitution. ( 0,611777117119183 )
Comput Math Methods Med - Noninvasive monitoring of hepatic damage from hepatitis C virus infection. ( 0,611060820109001 )
Comput. Biol. Med. - Phase lagging model of brain response to external stimuli-modeling of single action potential. ( 0,610105138992639 )
IEEE Trans Neural Netw Learn Syst - Global exponential synchronization of multiple memristive neural networks with time delay via nonlinear coupling. ( 0,609701395021063 )
Comput. Biol. Med. - Network and Nakamura tridiagonal computational simulation of electrically-conducting biopolymer micro-morphic transport phenomena. ( 0,609557910752413 )
Comput Methods Programs Biomed - Drug release profile in core-shell nanofibrous structures: a study on Peppas equation and artificial neural network modeling. ( 0,608815547318209 )
Neural Comput - On the continuous differentiability of inter-spike intervals of synaptically connected cortical spiking neurons in a neuronal network. ( 0,607118464873688 )
Comput Math Methods Med - Numerical solutions for a model of tissue invasion and migration of tumour cells. ( 0,603938441678774 )
Comput. Biol. Med. - Volume conductor models in surface electromyography: computational techniques. ( 0,602643405710774 )
Int J Neural Syst - Evolving RBF neural networks for adaptive soft-sensor design. ( 0,598818245352989 )
Lifetime Data Anal - An extended cure model and model selection. ( 0,596915245989028 )
IEEE Trans Image Process - Efficiency of semi-implicit schemes for anisotropic diffusion in the hypercube. ( 0,596761068155577 )
Neural Comput - How to compress sequential memory patterns into periodic oscillations: general reduction rules. ( 0,595709240166657 )
Comput Math Methods Med - Dynamics analysis and simulation of a modified HIV infection model with a saturated infection rate. ( 0,594279477889174 )
Comput Math Methods Med - Uncertainty quantification in simulations of epidemics using polynomial chaos. ( 0,594197084676958 )
Comput. Biol. Med. - ODE/PDE analysis of corneal curvature. ( 0,593540018120553 )
Neural Comput - What is the limit of redundancy reduction with divisive normalization? ( 0,593183684129025 )
Comput Biol Chem - A computational model for enhancing recombinant Penicillin G Acylase production from Escherichia coli DH5a. ( 0,591189617222078 )
Neural Comput - Intrinsic adaptation in autonomous recurrent neural networks. ( 0,5906955981813 )
Neural Comput - The computational power of interactive recurrent neural networks. ( 0,589947561150382 )
Comput Methods Programs Biomed - Modelling the Double Peak Phenomenon in pharmacokinetics. ( 0,587974732207334 )
Neural Comput - How sample paths of leaky integrate-and-fire models are influenced by the presence of a firing threshold. ( 0,585996924665972 )
Wiley Interdiscip Rev Syst Biol Med - A conceptual framework for computational models of Achilles tendon homeostasis. ( 0,58498738669103 )
Comput. Biol. Med. - Modelling and simulating reaction-diffusion systems using coloured Petri nets. ( 0,583863841312585 )
Comput. Biol. Med. - Discontinuous Galerkin finite element method for solving population density functions of cortical pyramidal and thalamic neuronal populations. ( 0,583211843519804 )
Neural Comput - A biological gradient descent for prediction through a combination of STDP and homeostatic plasticity. ( 0,583045906199188 )
Comput Math Methods Med - Solutions of a linearized mathematical model for capillary formation in tumor angiogenesis: an initial data perturbation approximation. ( 0,580906729269052 )
Comput Math Methods Med - Robust synchronization of delayed chaotic FitzHugh-Nagumo neurons under external electrical stimulation. ( 0,580235595851708 )
Comput. Biol. Med. - A compartment model of alveolar-capillary oxygen diffusion with ventilation-perfusion gradient and dynamics of air transport through the respiratory tract. ( 0,579873439463035 )
Brief. Bioinformatics - Inference of dynamic networks using time-course data. ( 0,579668716425171 )
Wiley Interdiscip Rev Syst Biol Med - Modeling the control of planar cell polarity. ( 0,578206324971108 )
Comput Methods Programs Biomed - Kinetic modelling of the role of the aldehyde dehydrogenase enzyme and the breast cancer resistance protein in drug resistance and transport. ( 0,577350269189626 )
Comput Math Methods Med - Multiscale coupling of transcranial direct current stimulation to neuron electrodynamics: modeling the influence of the transcranial electric field on neuronal depolarization. ( 0,577207625513776 )
Comput Math Methods Med - Large-scale modeling of epileptic seizures: scaling properties of two parallel neuronal network simulation algorithms. ( 0,574131048945263 )
J Chem Inf Model - Full and partial agonism of ionotropic glutamate receptors indicated by molecular dynamics simulations. ( 0,573639982099251 )
Comput Math Methods Med - Modeling schistosomiasis and HIV/AIDS codynamics. ( 0,573616996203332 )
Neural Comput - Learning the dynamics of objects by optimal functional interpolation. ( 0,573211504221111 )
IEEE Trans Image Process - Principal curves for lumen center extraction and flow channel width estimation in 3-D arterial networks: theory, algorithm, and validation. ( 0,571710648304871 )
Neural Comput - Neural dynamics, bifurcations, and firing rates in a quadratic integrate-and-fire model with a recovery variable. I: Deterministic behavior. ( 0,571144293686014 )
Comput Methods Programs Biomed - Epithelial to mesenchymal transition-the roles of cell morphology, labile adhesion and junctional coupling. ( 0,570764575610821 )
Med Decis Making - Cost-Effectiveness Uncertainty Analysis Methods: A Comparison of One-Way Sensitivity, Analysis of Covariance, and Expected Value of Partial Perfect Information. ( 0,57073567852012 )
Neural Comput - Diffusive information accumulation by minimal recurrent neural models of decision making. ( 0,570674209949288 )
Neural Comput - Sequential activity in asymmetrically coupled winner-take-all circuits. ( 0,570054234688327 )
Comput Biol Chem - Stochastic synchronization of interacting pathways in testosterone model. ( 0,567560753568522 )
IEEE Trans Image Process - Reinitialization-free level set evolution via reaction diffusion. ( 0,567438125667048 )
Neural Comput - Noninvertibility, chaotic coding, and chaotic multiplexity of synaptically modulated neural firing. ( 0,565689452656369 )
Comput. Biol. Med. - Examples of testing global identifiability of biological and biomedical models with the DAISY software. ( 0,56133872272258 )
Comput. Biol. Med. - Computing the stability of steady-state solutions of mathematical models of the electrical activity in the heart. ( 0,561292460702646 )
Comput Methods Programs Biomed - Simulating and analysing infectious disease data in a heterogeneous population with migration. ( 0,561142541945407 )
Neural Comput - Analysis of the stabilized supralinear network. ( 0,560156683619933 )
Comput Math Methods Med - A theoretical model for the transmission dynamics of the Buruli ulcer with saturated treatment. ( 0,559875449848332 )
Comput. Biol. Med. - On a reusable and multilevel methodology for modeling and simulation of pharmacokinetic-physiological systems: a preliminary study. ( 0,559393785719017 )
Comput. Biol. Med. - Numerical investigation into blood clotting at the bone-dental implant interface in the presence of an electrical stimulus. ( 0,558945366852791 )
Comput Math Methods Med - Complexity analysis and parameter estimation of dynamic metabolic systems. ( 0,55702599341214 )
Comput Math Methods Med - Understanding immunology via engineering design: the role of mathematical prototyping. ( 0,557021058398391 )
J Chem Inf Model - Fitting of dihedral terms in classical force fields as an analytic linear least-squares problem. ( 0,555476122008642 )