Res Synth Methods - A tool to assess the quality of a meta-analysis.

Tópicos

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{ model(2341) predict(2261) use(1141) }
{ data(3963) clinic(1234) research(1004) }
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{ assess(1506) score(1403) qualiti(1306) }
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{ can(981) present(881) function(850) }
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{ activ(1452) weight(1219) physic(1104) }
{ inform(2794) health(2639) internet(1427) }
{ measur(2081) correl(1212) valu(896) }
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{ patient(2315) diseas(1263) diabet(1191) }
{ problem(2511) optim(1539) algorithm(950) }
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{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
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{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
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{ gene(2352) biolog(1181) express(1162) }
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{ health(1844) social(1437) communiti(874) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ drug(1928) target(777) effect(648) }
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{ method(1969) cluster(1462) data(1082) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

CKGROUND: Because meta-analyses are increasingly prevalent and cited in the medical literature, it is important that tools are available to assess their methodological quality. When performing an empirical study of the quality of published meta-analyses, we found that existing tools did not place a strong emphasis on statistical and interpretational issues.METHODS: We developed a quality-assessment tool using existing materials and expert judgment as a starting point, followed by multiple iterations of input from our working group, piloting, and discussion. After having used the tool for our empirical study, agreement for four key items in the tool was measured using weighted kappa coefficients.RESULTS: Our tool contained 43 items divided into four key areas (data sources, analysis of individual studies, meta-analysis methods, and interpretation), and each area ended with a summary question. We also produced guidance for completing the tool. Agreement between raters was fair to moderate.CONCLUSIONS: The tool should usefully inform subsequent initiatives to develop quality-assessment tools for meta-analysis. We advocate use of consensus between independent raters when assessing statistical appropriateness and adequacy of interpretation in meta-analyses.

Resumo Limpo

ckground metaanalys increas preval cite medic literatur import tool avail assess methodolog qualiti perform empir studi qualiti publish metaanalys found exist tool place strong emphasi statist interpret issuesmethod develop qualityassess tool use exist materi expert judgment start point follow multipl iter input work group pilot discuss use tool empir studi agreement four key item tool measur use weight kappa coefficientsresult tool contain item divid four key area data sourc analysi individu studi metaanalysi method interpret area end summari question also produc guidanc complet tool agreement rater fair moderateconclus tool use inform subsequ initi develop qualityassess tool metaanalysi advoc use consensus independ rater assess statist appropri adequaci interpret metaanalys

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