Spat Spatiotemporal Epidemiol - The spread process of epidemic influenza in the continental United States, 1968-2008.

Tópicos

{ spatial(1525) area(1432) region(1030) }
{ state(1844) use(1261) util(961) }
{ measur(2081) correl(1212) valu(896) }
{ chang(1828) time(1643) increas(1301) }
{ method(2212) result(1239) propos(1039) }
{ treatment(1704) effect(941) patient(846) }
{ studi(1410) differ(1259) use(1210) }
{ compound(1573) activ(1297) structur(1058) }
{ research(1218) medic(880) student(794) }
{ data(2317) use(1299) case(1017) }
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{ cost(1906) reduc(1198) effect(832) }
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{ medic(1828) order(1363) alert(1069) }
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{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
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{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
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{ high(1669) rate(1365) level(1280) }
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{ method(1969) cluster(1462) data(1082) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

Understanding the quantitative disease dynamics of influenza is important in developing strategies to control its spread. This research analyzed the dominant spread process of epidemic influenza in the continental United States over a 41-year period. Spatial autocorrelation and simple correlation were applied to pneumonia and influenza mortality to observe the effect of distance and population on the between-state transmission of seasonal influenza. Annual influenza epidemics exhibited distance-based spatial spread at the peak of activity, but did not undergo significant population-based spread at any point. Geographically-close states (<500 miles) showed higher correlations in the start, peak and end of annual epidemics compared with geographically-distant states. Additionally, significant local clustering was found in the Midwest, Ohio River Valley and Northeastern regions as well as Nevada and Utah throughout an influenza season. This research may be combined with others in order to determine the main epidemic pathways of seasonal influenza in the US.

Resumo Limpo

understand quantit diseas dynam influenza import develop strategi control spread research analyz domin spread process epidem influenza continent unit state year period spatial autocorrel simpl correl appli pneumonia influenza mortal observ effect distanc popul betweenst transmiss season influenza annual influenza epidem exhibit distancebas spatial spread peak activ undergo signific populationbas spread point geographicallyclos state mile show higher correl start peak end annual epidem compar geographicallydist state addit signific local cluster found midwest ohio river valley northeastern region well nevada utah throughout influenza season research may combin other order determin main epidem pathway season influenza us

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