Spat Spatiotemporal Epidemiol - The integration of molecular tools into veterinary and spatial epidemiology.

Tópicos

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{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

At the interface of molecular biology and epidemiology, the emerging discipline of molecular epidemiology offers unique opportunities to advance the study of diseases through the investigation of infectious agents at the molecular level. Molecular tools can increase our understanding of the factors that shape the spatial and temporal distribution of pathogens and disease. Both spatial and molecular aspects have always been important to the field of infectious disease epidemiology, but recently news tools have been developed which increase our ability to consider both elements within a common framework. This enables the epidemiologist to make inferences about disease patterns in space and time. This paper introduces some basic concepts of molecular epidemiology in a veterinary context and illustrates the application of molecular tools at a range of spatio-temporal scales. Case studies - a multi-state outbreak of Serratia mastitis, a national control program for campylobacteriosis, and evolution of foot-and-mouth-disease viruses - are used to demonstrate the importance of considering molecular aspects in modern epidemiological studies. The discipline of molecular epidemiology is in its infancy and our contribution aims to promote awareness, understanding and uptake of molecular epidemiology in veterinary science.

Resumo Limpo

interfac molecular biolog epidemiolog emerg disciplin molecular epidemiolog offer uniqu opportun advanc studi diseas investig infecti agent molecular level molecular tool can increas understand factor shape spatial tempor distribut pathogen diseas spatial molecular aspect alway import field infecti diseas epidemiolog recent news tool develop increas abil consid element within common framework enabl epidemiologist make infer diseas pattern space time paper introduc basic concept molecular epidemiolog veterinari context illustr applic molecular tool rang spatiotempor scale case studi multist outbreak serratia mastiti nation control program campylobacteriosi evolut footandmouthdiseas virus use demonstr import consid molecular aspect modern epidemiolog studi disciplin molecular epidemiolog infanc contribut aim promot awar understand uptak molecular epidemiolog veterinari scienc

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