Wiley Interdiscip Rev Syst Biol Med - Network biology: a direct approach to study biological function.

Tópicos

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Resumo

In this paper we discuss the dualism of gene networks and their role in systems biology. We argue that gene networks (1) can serve as a conceptual framework, forming a fundamental level of a phenomenological description, and (2) are a means to represent and analyze data. The latter point does not only allow a systems analysis but is even amenable for a direct approach to study biological function. Here we focus on the clarity of our main arguments and conceptual meaning of gene networks, rather than the causal inference of gene networks from data. WIREs Syst Biol Med 2011 3 379-391 DOI: 10.1002/wsbm.134 For further resources related to this article, please visit the WIREs website.

Resumo Limpo

paper discuss dualism gene network role system biolog argu gene network can serv conceptu framework form fundament level phenomenolog descript mean repres analyz data latter point allow system analysi even amen direct approach studi biolog function focus clariti main argument conceptu mean gene network rather causal infer gene network data wire syst biol med doi wsbm resourc relat articl pleas visit wire websit

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