Brief. Bioinformatics - Bioinformatics tools and database resources for systems genetics analysis in mice--a short review and an evaluation of future needs.

Tópicos

{ data(1714) softwar(1251) tool(1186) }
{ data(2317) use(1299) case(1017) }
{ intervent(3218) particip(2042) group(1664) }
{ studi(2440) review(1878) systemat(933) }
{ data(3963) clinic(1234) research(1004) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ ehr(2073) health(1662) electron(1139) }
{ time(1939) patient(1703) rate(768) }
{ can(774) often(719) complex(702) }
{ extract(1171) text(1153) clinic(932) }
{ design(1359) user(1324) use(1319) }
{ research(1218) medic(880) student(794) }
{ medic(1828) order(1363) alert(1069) }
{ data(3008) multipl(1320) sourc(1022) }
{ structur(1116) can(940) graph(676) }
{ imag(1057) registr(996) error(939) }
{ sequenc(1873) structur(1644) protein(1328) }
{ take(945) account(800) differ(722) }
{ assess(1506) score(1403) qualiti(1306) }
{ framework(1458) process(801) describ(734) }
{ howev(809) still(633) remain(590) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ visual(1396) interact(850) tool(830) }
{ state(1844) use(1261) util(961) }
{ gene(2352) biolog(1181) express(1162) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ use(976) code(926) identifi(902) }
{ survey(1388) particip(1329) question(1065) }
{ decis(3086) make(1611) patient(1517) }
{ detect(2391) sensit(1101) algorithm(908) }
{ model(3404) distribut(989) bayesian(671) }
{ imag(1947) propos(1133) code(1026) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ measur(2081) correl(1212) valu(896) }
{ bind(1733) structur(1185) ligand(1036) }
{ method(1219) similar(1157) match(930) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ motion(1329) object(1292) video(1091) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ problem(2511) optim(1539) algorithm(950) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ method(1557) propos(1049) approach(1037) }
{ control(1307) perform(991) simul(935) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ general(901) number(790) one(736) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ model(3480) simul(1196) paramet(876) }
{ monitor(1329) mobil(1314) devic(1160) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ age(1611) year(1155) adult(843) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ first(2504) two(1366) second(1323) }
{ activ(1138) subject(705) human(624) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ implement(1333) system(1263) develop(1122) }
{ estim(2440) model(1874) function(577) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }

Resumo

During a meeting of the SYSGENET working group 'Bioinformatics', currently available software tools and databases for systems genetics in mice were reviewed and the needs for future developments discussed. The group evaluated interoperability and performed initial feasibility studies. To aid future compatibility of software and exchange of already developed software modules, a strong recommendation was made by the group to integrate HAPPY and R/qtl analysis toolboxes, GeneNetwork and XGAP database platforms, and TIQS and xQTL processing platforms. R should be used as the principal computer language for QTL data analysis in all platforms and a 'cloud' should be used for software dissemination to the community. Furthermore, the working group recommended that all data models and software source code should be made visible in public repositories to allow a coordinated effort on the use of common data structures and file formats.

Resumo Limpo

meet sysgenet work group bioinformat current avail softwar tool databas system genet mice review need futur develop discuss group evalu interoper perform initi feasibl studi aid futur compat softwar exchang alreadi develop softwar modul strong recommend made group integr happi rqtl analysi toolbox genenetwork xgap databas platform tiq xqtl process platform r use princip comput languag qtl data analysi platform cloud use softwar dissemin communiti furthermor work group recommend data model softwar sourc code made visibl public repositori allow coordin effort use common data structur file format

Resumos Similares

BMC Med Inform Decis Mak - Text data extraction for a prospective, research-focused data mart: implementation and validation. ( 0,762735247674911 )
Methods Inf Med - Enabling GeneHunter as a grid service: a case study for implementing analytical services in biomedical grids. ( 0,76250796561486 )
J Chem Inf Model - CYANOS: a data management system for natural product drug discovery efforts using cultured microorganisms. ( 0,760858716350868 )
Appl Clin Inform - Design and multicentric implementation of a generic software architecture for patient recruitment systems re-using existing HIS tools and routine patient data. ( 0,758241304685982 )
BMC Med Inform Decis Mak - Clinical software development for the Web: lessons learned from the BOADICEA project. ( 0,757373316040682 )
Int J Health Geogr - Open-Source web-based Geographical Information System for health exposure assessment. ( 0,754371634761864 )
J Biomed Inform - Cloud-based bioinformatics workflow platform for large-scale next-generation sequencing analyses. ( 0,753980423117096 )
J Chem Inf Model - JGromacs: a Java package for analyzing protein simulations. ( 0,753833856422101 )
Int J Comput Assist Radiol Surg - Development and implementation of an integrated mobile situational awareness iPhone application VigiVU? at an academic medical center. ( 0,751268563317596 )
J Biomed Inform - The Analytic Information Warehouse (AIW): a platform for analytics using electronic health record data. ( 0,745506284984113 )
J Am Med Inform Assoc - Bionimbus: a cloud for managing, analyzing and sharing large genomics datasets. ( 0,744547016879234 )
Methods Inf Med - MITK diffusion imaging. ( 0,736416930006986 )
Comput Methods Programs Biomed - Open source EMR software: profiling, insights and hands-on analysis. ( 0,732363098151139 )
J Med Syst - A data types profile suitable for use with ISO EN 13606. ( 0,731336501368075 )
J Chem Inf Model - DockoMatic 2.0: high throughput inverse virtual screening and homology modeling. ( 0,723569400598836 )
J Digit Imaging - Development and evaluation of a low-cost and high-capacity DICOM image data storage system for research. ( 0,723356283280805 )
Brief. Bioinformatics - Architecture for interoperable software in biology. ( 0,71681807557408 )
Curr Protoc Bioinformatics - Using EMBL-EBI Services via Web Interface and Programmatically via Web Services. ( 0,713900238966606 )
Comput Methods Programs Biomed - Raw data extraction from electrocardiograms with Portable Document Format. ( 0,710899434038838 )
Comput Methods Programs Biomed - Facilitating pharmacometric workflow with the metrumrg package for R. ( 0,707171767925672 )
J Am Med Inform Assoc - Enabling collaborative research using the Biomedical Informatics Research Network (BIRN). ( 0,7061583195651 )
AMIA Annu Symp Proc - ARX--A Comprehensive Tool for Anonymizing Biomedical Data. ( 0,704113733605326 )
Comput Methods Programs Biomed - An open source tool for heart rate variability spectral analysis. ( 0,703447461967716 )
Methods Inf Med - Supporting translational research on inherited cardiomyopathies through information technology. ( 0,702823955657889 )
J Med Syst - Impact of the Patient-Reported Outcomes Management Information System (PROMIS) upon the design and operation of multi-center clinical trials: a qualitative research study. ( 0,702479026958442 )
Int J Comput Assist Radiol Surg - The Medical Imaging Interaction Toolkit: challenges and advances : 10 years of open-source development. ( 0,701306307613514 )
Int J Health Geogr - Neighborhood deprivation, vehicle ownership, and potential spatial access to a variety of fruits and vegetables in a large rural area in Texas. ( 0,699709714277148 )
J Med Syst - LAS: a software platform to support oncological data management. ( 0,693591867967549 )
Brief. Bioinformatics - Web scraping technologies in an API world. ( 0,692858393215948 )
J Integr Bioinform - Bioinformatics strategies in life sciences: from data processing and data warehousing to biological knowledge extraction. ( 0,685025509244738 )
Comput. Biol. Med. - A robust and extendible framework for medical image registration focused on rapid clinical application deployment. ( 0,684954825670793 )
AMIA Annu Symp Proc - Information warehouse - a comprehensive informatics platform for business, clinical, and research applications. ( 0,683593912981509 )
Int J Med Inform - The Epilepsy Phenome/Genome Project (EPGP) informatics platform. ( 0,681470613736628 )
Health Informatics J - Implementation of integrated heterogeneous electronic electrocardiography data into Maharaj Nakorn Chiang Mai Hospital Information System. ( 0,67496840238166 )
J Biomed Inform - Modular design, application architecture, and usage of a self-service model for enterprise data delivery: the Duke Enterprise Data Unified Content Explorer (DEDUCE). ( 0,671105839014027 )
J Integr Bioinform - BacillOndex: an integrated data resource for systems and synthetic biology. ( 0,670984346956497 )
Comput Methods Programs Biomed - Using off-the-shelf tools for terabyte-scale waveform recording in intensive care: computer system design, database description and lessons learned. ( 0,670179521869459 )
AMIA Annu Symp Proc - The SHARPn project on secondary use of Electronic Medical Record data: progress, plans, and possibilities. ( 0,669604225483837 )
J Telemed Telecare - A mobile-phone immunization record in Ontario: uptake and opportunities for improving public health. ( 0,66535453950133 )
Methods Inf Med - Missing semantic annotation in databases. The root cause for data integration and migration problems in information systems. ( 0,665293247233714 )
J Chem Inf Model - ThermoData Engine (TDE): software implementation of the dynamic data evaluation concept. 9. Extensible thermodynamic constraints for pure compounds and new model developments. ( 0,665073086798303 )
J. Med. Internet Res. - WikiBuild: a new online collaboration process for multistakeholder tool development and consensus building. ( 0,661317338286965 )
Methods Inf Med - Secure Secondary Use of Clinical Data with Cloud-based NLP Services. Towards a Highly Scalable Research Infrastructure. ( 0,658320989488566 )
J Chem Inf Model - Fragment-based docking: development of the CHARMMing Web user interface as a platform for computer-aided drug design. ( 0,657553450016297 )
AMIA Annu Symp Proc - Enabling cross-platform clinical decision support through Web-based decision support in commercial electronic health record systems: proposal and evaluation of initial prototype implementations. ( 0,656432902036932 )
J Med Syst - Development and evaluation of tools for measuring the quality of experience (QoE) in mHealth applications. ( 0,656284155948949 )
J Chem Inf Model - A general sequence processing and analysis program for protein engineering. ( 0,655255361294203 )
J Am Med Inform Assoc - Taking advantage of continuity of care documents to populate a research repository. ( 0,654015800718988 )
Int J Med Inform - A review of ECG storage formats. ( 0,653313666993607 )
Appl Clin Inform - An information retrieval system for computerized patient records in the context of a daily hospital practice: the example of the L?on B?rard Cancer Center (France). ( 0,651021404148098 )
Comput Methods Programs Biomed - Biomechanical ToolKit: Open-source framework to visualize and process biomechanical data. ( 0,649616291566668 )
J Clin Monit Comput - Integrating Arden-Syntax-based clinical decision support with extended presentation formats into a commercial patient data management system. ( 0,649578069901559 )
Int J Health Geogr - Review of software for space-time disease surveillance. ( 0,646978287249084 )
Comput. Biol. Med. - POTAMOS mass spectrometry calculator: computer aided mass spectrometry to the post-translational modifications of proteins. A focus on histones. ( 0,646854196907887 )
Comput. Biol. Med. - IVUSAngio tool: a publicly available software for fast and accurate 3D reconstruction of coronary arteries. ( 0,646853131722803 )
Brief. Bioinformatics - The NGS WikiBook: a dynamic collaborative online training effort with long-term sustainability. ( 0,6446397133654 )
BMC Med Inform Decis Mak - PKreport: report generation for checking population pharmacokinetic model assumptions. ( 0,642057234359673 )
Brief. Bioinformatics - A toolbox for developing bioinformatics software. ( 0,631962393429652 )
J Chem Inf Model - DDLm: a new dictionary definition language. ( 0,631111803689602 )
BMC Med Inform Decis Mak - XML-BSPM: an XML format for storing Body Surface Potential Map recordings. ( 0,630874726279404 )
Int J Med Robot - Finite element modelling of maxillofacial surgery and facial expressions--a preliminary study. ( 0,629563661573989 )
J Chem Inf Model - CycloPs: generating virtual libraries of cyclized and constrained peptides including nonnatural amino acids. ( 0,628861707472425 )
J Chem Inf Model - ZINC: a free tool to discover chemistry for biology. ( 0,627053403689588 )
J Med Syst - COSARA: integrated service platform for infection surveillance and antibiotic management in the ICU. ( 0,626989529838405 )
Curr Protoc Bioinformatics - APPENDIX 1B Common File Formats. ( 0,625870769806039 )
IEEE Trans Vis Comput Graph - A Survey of Software Frameworks for Cluster-Based Large High-Resolution Displays. ( 0,624502257547382 )
Int J Comput Assist Radiol Surg - A PACS archive architecture supported on cloud services. ( 0,624357274149404 )
Artif Intell Med - Classification integration and reclassification using constraint databases. ( 0,623886408396377 )
J Chem Inf Model - AsteriX: a Web server to automatically extract ligand coordinates from figures in PDF articles. ( 0,623380929323355 )
J Am Med Inform Assoc - Enabling distributed electronic research data collection for a rural Appalachian tobacco cessation study. ( 0,619839414746767 )
Inform Health Soc Care - arriba-lib: Analyses of user interactions with an electronic library of decision aids on the basis of log data. ( 0,618553887733766 )
J Chem Inf Model - hERG me out. ( 0,617915677380274 )
BMC Med Inform Decis Mak - The Computer-based Health Evaluation Software (CHES): a software for electronic patient-reported outcome monitoring. ( 0,617132932758139 )
Brief. Bioinformatics - Online tools for understanding rat physiology. ( 0,616329725624971 )
J Chem Inf Model - 3-D QSAutogrid/R: an alternative procedure to build 3-D QSAR models. Methodologies and applications. ( 0,616296972617076 )
Comput Methods Programs Biomed - Kubios HRV--heart rate variability analysis software. ( 0,615163269831349 )
Comput Methods Programs Biomed - Social Web mining and exploitation for serious applications: Technosocial Predictive Analytics and related technologies for public health, environmental and national security surveillance. ( 0,614692524388538 )
J Chem Inf Model - Development of an informatics platform for therapeutic protein and peptide analytics. ( 0,613998834830375 )
Healthc (Amst) - Supporting HITECH implementation and assessing lessons for the future: The role of program evaluation. ( 0,613903577274041 )
Appl Clin Inform - Unlocking Data for Clinical Research - The German i2b2 Experience. ( 0,613058420927152 )
Int J Health Geogr - Displaying R spatial statistics on Google dynamic maps with web applications created by Rwui. ( 0,612651840297105 )
J Integr Bioinform - A flexible statistics web processing service--added value for information systems for experiment data. ( 0,612449766062427 )
Comput Methods Programs Biomed - Clustering of distinct PACS archives using a cooperative peer-to-peer network. ( 0,611633117931866 )
J Chem Inf Model - ChemCalc: a building block for tomorrow's chemical infrastructure. ( 0,611604775890594 )
Curr Protoc Bioinformatics - Using PeptideAtlas, SRMAtlas, and PASSEL: Comprehensive Resources for Discovery and Targeted Proteomics. ( 0,611603617230806 )
BMC Med Inform Decis Mak - Applying representational state transfer (REST) architecture to archetype-based electronic health record systems. ( 0,611267669711464 )
Methods Inf Med - The integration of the risk management process with the lifecycle of medical device software. ( 0,611227667646694 )
J Chem Inf Model - Atomdroid: a computational chemistry tool for mobile platforms. ( 0,610898646958708 )
J Am Med Inform Assoc - An ontology-driven, diagnostic modeling system. ( 0,610797410825211 )
Comput Methods Programs Biomed - Software for quantitative analysis of radiotherapy: overview, requirement analysis and design solutions. ( 0,607268910974459 )
J Med Syst - A generative tool for building health applications driven by ISO 13606 archetypes. ( 0,606819581345068 )
J Med Syst - Predefined three tier business intelligence architecture in healthcare enterprise. ( 0,605554762416253 )
Methods Inf Med - An epidemiological modeling and data integration framework. ( 0,605317681510264 )
Comput Methods Programs Biomed - PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel. ( 0,604866270572856 )
J. Med. Internet Res. - How strong are passwords used to protect personal health information in clinical trials? ( 0,603846998251999 )
IEEE J Biomed Health Inform - Hardware and software realization of EDSD for acupuncture research and practice. ( 0,603807199289676 )
Brief. Bioinformatics - Software applications for flux balance analysis. ( 0,603382419027425 )
Methods Inf Med - UceWeb: a web-based collaborative tool for collecting and sharing quality of life data. ( 0,603166160494678 )
AMIA Annu Symp Proc - eEvidence: Information Seeking Support for Evidence-based Practice: An Implementation Case Study. ( 0,602226881894709 )
Comput Methods Programs Biomed - Warehousing re-annotated cancer genes for biomarker meta-analysis. ( 0,601676766702752 )