Comput Biol Chem - Identification of miR159s and their target genes and expression analysis under drought stress in potato.

Tópicos

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Resumo

The MYB proteins comprise one of the largest families of plant transcription factors (TFs) and many of MYB families, which play essential roles in plant growth, development and respond to environmental stresses, and have yet been identified in plant. Previous research has shown that miR159 family members repressed the conserved plant R2R3 MYB domain TFs in model plants. In the present research, we identified three potato novel miR159 family members named as stu-miR159a, stu-miR159b and stu-miR159c based on bioinformatics analysis. Target prediction showed that they have a bite sit on the three GAMyb-like genes (StGAMyb-like1, StGAMyb-like2.1 and StGAMyb-like2.2) of potato. Those GAMyb-like genes also have been selected and cloned from potato, which belong to R2R3 MYB domain TFs. We further measured expressional levels of stu-miR159s and potato GAMyb-like genes during the different periods of drought treated samples using quantitative real-time PCR (qRT-PCR). The results showed that they had a opposite expression pattern, briefly, three stu-miR159 members showed similar expressional trends which were significantly decreased expression after experiencing 25 days of drought stress treatment, while the potato GAMyb-like family members were greatly increased. Therefore, we suggested that stu-miR159s negatively regulated the expression of potato GAMyb-like genes which responsible for drought stress. The findings can facilitate functional studies of miRNAs in plants and provide molecular evidence for involvement process of drought tolerance in potato.

Resumo Limpo

myb protein compris one largest famili plant transcript factor tfs mani myb famili play essenti role plant growth develop respond environment stress yet identifi plant previous research shown mir famili member repress conserv plant rr myb domain tfs model plant present research identifi three potato novel mir famili member name stumira stumirb stumirc base bioinformat analysi target predict show bite sit three gamyblik gene stgamyblik stgamyblik stgamyblik potato gamyblik gene also select clone potato belong rr myb domain tfs measur expression level stumir potato gamyblik gene differ period drought treat sampl use quantit realtim pcr qrtpcr result show opposit express pattern briefli three stumir member show similar expression trend signific decreas express experienc day drought stress treatment potato gamyblik famili member great increas therefor suggest stumir negat regul express potato gamyblik gene respons drought stress find can facilit function studi mirna plant provid molecular evid involv process drought toler potato

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