Comput Biol Chem - Data-based modeling and prediction of cytotoxicity induced by contaminants in water resources.

Tópicos

{ model(2220) cell(1177) simul(1124) }
{ model(2341) predict(2261) use(1141) }
{ model(3480) simul(1196) paramet(876) }
{ model(2656) set(1616) predict(1553) }
{ monitor(1329) mobil(1314) devic(1160) }
{ error(1145) method(1030) estim(1020) }
{ chang(1828) time(1643) increas(1301) }
{ record(1888) medic(1808) patient(1693) }
{ implement(1333) system(1263) develop(1122) }
{ assess(1506) score(1403) qualiti(1306) }
{ gene(2352) biolog(1181) express(1162) }
{ structur(1116) can(940) graph(676) }
{ process(1125) use(805) approach(778) }
{ imag(1947) propos(1133) code(1026) }
{ inform(2794) health(2639) internet(1427) }
{ measur(2081) correl(1212) valu(896) }
{ featur(3375) classif(2383) classifi(1994) }
{ learn(2355) train(1041) set(1003) }
{ method(984) reconstruct(947) comput(926) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ system(1050) medic(1026) inform(1018) }
{ visual(1396) interact(850) tool(830) }
{ state(1844) use(1261) util(961) }
{ data(2317) use(1299) case(1017) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ first(2504) two(1366) second(1323) }
{ cancer(2502) breast(956) screen(824) }
{ model(3404) distribut(989) bayesian(671) }
{ can(774) often(719) complex(702) }
{ data(1737) use(1416) pattern(1282) }
{ system(1976) rule(880) can(841) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ method(1219) similar(1157) match(930) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ take(945) account(800) differ(722) }
{ studi(2440) review(1878) systemat(933) }
{ motion(1329) object(1292) video(1091) }
{ treatment(1704) effect(941) patient(846) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ problem(2511) optim(1539) algorithm(950) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ algorithm(1844) comput(1787) effici(935) }
{ extract(1171) text(1153) clinic(932) }
{ method(1557) propos(1049) approach(1037) }
{ data(1714) softwar(1251) tool(1186) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ care(1570) inform(1187) nurs(1089) }
{ general(901) number(790) one(736) }
{ search(2224) databas(1162) retriev(909) }
{ howev(809) still(633) remain(590) }
{ data(3963) clinic(1234) research(1004) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ import(1318) role(1303) understand(862) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ spatial(1525) area(1432) region(1030) }
{ health(3367) inform(1360) care(1135) }
{ ehr(2073) health(1662) electron(1139) }
{ research(1218) medic(880) student(794) }
{ patient(2837) hospit(1953) medic(668) }
{ age(1611) year(1155) adult(843) }
{ cost(1906) reduc(1198) effect(832) }
{ group(2977) signific(1463) compar(1072) }
{ sampl(1606) size(1419) use(1276) }
{ data(3008) multipl(1320) sourc(1022) }
{ intervent(3218) particip(2042) group(1664) }
{ activ(1138) subject(705) human(624) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ health(1844) social(1437) communiti(874) }
{ high(1669) rate(1365) level(1280) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ drug(1928) target(777) effect(648) }
{ result(1111) use(1088) new(759) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ activ(1452) weight(1219) physic(1104) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

This paper is concerned with dynamic modeling, prediction and analysis of cell cytotoxicity induced by water contaminants. A real-time cell electronic sensing (RT-CES) system has been used for continuously monitoring dynamic cytotoxicity responses of living cells. Cells are grown onto the surfaces of the microelectronic sensors. Changes in cell number expressed as cell index (CI) have been recorded on-line as time series. The CI data are used to develop dynamic prediction models for cell cytotoxicity process. We consider support vector regression (SVR) algorithm to implement data-based system identification for dynamic modeling and prediction of cytotoxicity. Through several validation studies, multi-step-ahead predictions are calculated and compared with the actual CI obtained from experiments. It is shown that SVR-based dynamic modeling has great potential in predicting the cytotoxicity response of the cells in the presence of toxicant.

Resumo Limpo

paper concern dynam model predict analysi cell cytotox induc water contamin realtim cell electron sens rtces system use continu monitor dynam cytotox respons live cell cell grown onto surfac microelectron sensor chang cell number express cell index ci record onlin time seri ci data use develop dynam predict model cell cytotox process consid support vector regress svr algorithm implement databas system identif dynam model predict cytotox sever valid studi multistepahead predict calcul compar actual ci obtain experi shown svrbase dynam model great potenti predict cytotox respons cell presenc toxic

Resumos Similares

Comput. Biol. Med. - First-principles modeling of fluid and solute exchange in the human during normal and hemodialysis conditions. ( 0,754146687076673 )
J. Comput. Biol. - Cytopede: a three-dimensional tool for modeling cell motility on a flat surface. ( 0,689880514859676 )
Comput Methods Programs Biomed - A phenomenological mathematical model of the articular cartilage damage. ( 0,683682080855776 )
Comput Math Methods Med - Quantitative imaging of young's modulus of soft tissues from ultrasound water jet indentation: a finite element study. ( 0,673928750397736 )
Med Biol Eng Comput - Temporal evolution of skeletal regenerated tissue: what can mechanical investigation add to biological? ( 0,663891491275185 )
Med Biol Eng Comput - A grip force model for the da Vinci end-effector to predict a compensation force. ( 0,660850746478058 )
Med Biol Eng Comput - Biomechanical modeling of brace treatment of scoliosis: effects of gravitational loads. ( 0,659267297927966 )
J Integr Bioinform - Space-time dynamics of stem cell niches: a unified approach for plants. ( 0,655374946973694 )
Med Biol Eng Comput - Biomechanical characterisation of fresh and cadaverous human small intestine: applications for abdominal trauma. ( 0,64910879088929 )
Comput Math Methods Med - A review of the combination of experimental measurements and fibril-reinforced modeling for investigation of articular cartilage and chondrocyte response to loading. ( 0,642078408243261 )
Med Biol Eng Comput - A new method to include the gravitational forces in a finite element model of the scoliotic spine. ( 0,639510164112856 )
Med Biol Eng Comput - Investigation of foot plantar pressure: experimental and numerical analysis. ( 0,633455763571197 )
Comput Math Methods Med - Superficial collagen fibril modulus and pericellular fixed charge density modulate chondrocyte volumetric behaviour in early osteoarthritis. ( 0,633194086148266 )
Comput Methods Programs Biomed - Anthropometric dependence of the response of a thorax FE model under high speed loading: validation and real world accident replication. ( 0,633090168847907 )
IEEE Trans Vis Comput Graph - A Hexahedral Multigrid Approach for Simulating Cuts in Deformable Objects. ( 0,631201547306417 )
Med Biol Eng Comput - Change of mechanical vertebrae properties due to progressive osteoporosis: combined biomechanical and finite-element analysis within a rat model. ( 0,630510576604162 )
Int J Comput Assist Radiol Surg - Quasi-linear viscoelastic modeling of arterial wall for surgical simulation. ( 0,629449558659055 )
Med Biol Eng Comput - In-silico modeling of atrial repolarization in normal and atrial fibrillation remodeled state. ( 0,627460888118535 )
Comput Methods Programs Biomed - Computational analysis of cartilage implants based on an interpenetrated polymer network for tissue repairing. ( 0,623841277606894 )
Comput Methods Programs Biomed - Monte Carlo method for photon heating using temperature-dependent optical properties. ( 0,622638163171631 )
Med Biol Eng Comput - Modeling and experimental methods to predict oxygen distribution in bone defects following cell transplantation. ( 0,621937425308776 )
Med Biol Eng Comput - Effects of simulated injury on the anteroinferior glenohumeral capsule. ( 0,621819738503528 )
Comput Methods Programs Biomed - Experiment and hydro-mechanical coupling simulation study on the human periodontal ligament. ( 0,621618772670888 )
Comput Methods Programs Biomed - An FDTD-based computer simulation platform for shock wave propagation in electrohydraulic lithotripsy. ( 0,621477204852428 )
Comput Math Methods Med - Study of tumor growth under hyperthermia condition. ( 0,619020763599535 )
Comput Math Methods Med - On the stability of lung parenchymal lesions with applications to early pneumothorax diagnosis. ( 0,617776581495918 )
Comput. Biol. Med. - Biological-data-based finite-element stress analysis of mandibular bone with implant-supported overdenture. ( 0,617592314336456 )
Med Biol Eng Comput - A three-dimensional finite element model of the cervical spine: an investigation of whiplash injury. ( 0,615046556360889 )
Med Biol Eng Comput - Influence of ischemic core muscle fibers on surface depolarization potentials in superfused cardiac tissue preparations: a simulation study. ( 0,614798997023619 )
Comput Methods Programs Biomed - Epithelial to mesenchymal transition-the roles of cell morphology, labile adhesion and junctional coupling. ( 0,61428659639399 )
Comput Methods Programs Biomed - Subject-specific finite element simulation of the human femur considering inhomogeneous material properties: a straightforward method and convergence study. ( 0,614204790279019 )
Comput Math Methods Med - Recent advances in computational mechanics of the human knee joint. ( 0,614201463899873 )
Med Biol Eng Comput - Sensitivity studies of pediatric material properties on juvenile lumbar spine responses using finite element analysis. ( 0,614094819813754 )
Med Biol Eng Comput - Biomechanical analysis of the effects of medial meniscectomy on degenerative osteoarthritis. ( 0,612671664853987 )
Comput Math Methods Med - A finite element study of micropipette aspiration of single cells: effect of compressibility. ( 0,611502102154546 )
Med Biol Eng Comput - 3D finite element analysis on esthetic indirect dental restorations under thermal and mechanical loading. ( 0,611401638365573 )
J Integr Bioinform - Stochastic simulation of the spatio-temporal dynamics of reaction-diffusion systems: the case for the bicoid gradient. ( 0,611349530125025 )
Med Biol Eng Comput - Parameter estimation of the copernicus decompression model with venous gas emboli in human divers. ( 0,609448157928479 )
Comput Biol Chem - Modeling of tumor growth in dendritic cell-based immunotherapy using artificial neural networks. ( 0,608500496938958 )
Int J Comput Assist Radiol Surg - Bivariate optimization of orthodontic mini-implant thread height and pitch. ( 0,608070056172495 )
Med Biol Eng Comput - Can common adhesion molecules and microtopography affect cellular elasticity? A combined atomic force microscopy and optical study. ( 0,608025956022879 )
Med Biol Eng Comput - Sound transmission in the chest under surface excitation: an experimental and computational study with diagnostic applications. ( 0,607291516382729 )
Comput Math Methods Med - A computational modeling approach for investigating soft tissue balancing in bicruciate retaining knee arthroplasty. ( 0,605134279066405 )
Comput Math Methods Med - Contribution to the determination of in vivo mechanical characteristics of human skin by indentation test. ( 0,604732476822561 )
Comput. Biol. Med. - Prediction of stress shielding around an orthopedic screw: using stress and strain energy density as mechanical stimuli. ( 0,599239747565845 )
Comput Math Methods Med - Dynamics of posttranslational modifications of p53. ( 0,598746056943193 )
Med Biol Eng Comput - The remodeling of alveolar bone supporting the mandibular first molar with different levels of periodontal attachment. ( 0,598725182250735 )
Comput Methods Programs Biomed - Growth plate stress distribution implications during bone development: a simple framework computational approach. ( 0,598622642316108 )
Int J Comput Assist Radiol Surg - In-silico oncology: an approximate model of brain tumor mass effect based on directly manipulated free form deformation. ( 0,598164429391203 )
Med Biol Eng Comput - A quasi-brittle continuum damage finite element model of the human proximal femur based on element deletion. ( 0,595540228817232 )
Comput. Biol. Med. - Computational studies on strain transmission from a collagen gel construct to a cell and its internal cytoskeletal filaments. ( 0,59486195696196 )
Artif Intell Med - A growth model of human papillomavirus type 16 designed from cellular automata and agent-based models. ( 0,594183122026282 )
Comput. Biol. Med. - Modeling of tumor growth undergoing virotherapy. ( 0,594149393633482 )
J Integr Bioinform - A model of phospholipid biosynthesis in tumor in response to an anticancer agent in vivo. ( 0,593764567858363 )
Comput Math Methods Med - Constitutive modeling of time-dependent response of human plantar aponeurosis. ( 0,593296516749793 )
Comput Methods Programs Biomed - Optimal bone density distributions: numerical analysis of the osteocyte spatial influence in bone remodeling. ( 0,593095673630779 )
Int J Comput Assist Radiol Surg - Multi-scale model for investigating the electrical properties and mechanical properties of liver tissue undergoing ablation. ( 0,592727133785992 )
Med Biol Eng Comput - Development of a subject-specific model to predict the forces in the knee ligaments at high flexion angles. ( 0,592457603796537 )
Sci Data - Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies. ( 0,592114816956928 )
Comput. Biol. Med. - Dynamic finite element analysis and moving particle simulation of human enamel on a microscale. ( 0,59119367757561 )
Med Biol Eng Comput - Computer simulation of three-dimensional plaque formation and progression in the carotid artery. ( 0,590484860452153 )
Comput. Biol. Med. - Biomechanical simulation of various surface roughnesses and geometric designs on an immediately loaded dental implant. ( 0,590309006481059 )
Wiley Interdiscip Rev Syst Biol Med - Virtual Cell: computational tools for modeling in cell biology. ( 0,589970278204275 )
Med Biol Eng Comput - Modeling and analysis of coagulated liver tissue and its interaction with a scalpel blade. ( 0,589441835336004 )
Med Biol Eng Comput - Sensitivity of patient-specific vertebral finite element model from low dose imaging to material properties and loading conditions. ( 0,58929254328448 )
Med Biol Eng Comput - Mechanical and microarchitectural analyses of cancellous bone through experiment and computer simulation. ( 0,589098477798081 )
Comput Math Methods Med - Morphological measurement of living cells in methanol with digital holographic microscopy. ( 0,588838323433453 )
Comput. Biol. Med. - Protein transport in the connecting cilium of a photoreceptor cell: modeling the effects of bidirectional protein transitions between the diffusion-driven and motor-driven kinetic states. ( 0,586415270971404 )
Med Biol Eng Comput - Multi-scale study of nanoparticle transport and deposition in tissues during an injection process. ( 0,58544285798229 )
Comput. Biol. Med. - Modeling porous scaffold microstructure by a reaction-diffusion system and its degradation by hydrolysis. ( 0,584898486939193 )
Comput. Biol. Med. - Finite element modelling of diseased carotid bifurcations generated from in vivo computerised tomographic angiography. ( 0,584405485103263 )
Comput Math Methods Med - Time-course analysis of main markers of primary infection in cats with the feline immunodeficiency virus. ( 0,584339196579106 )
Med Biol Eng Comput - Finite element modeling of mitral leaflet tissue using a layered shell approximation. ( 0,584114646260597 )
Comput Methods Programs Biomed - 3D reconstruction of TMJ after resection of the cyst and the stress-strain analyses. ( 0,583942415367209 )
Med Biol Eng Comput - Biomechanical analysis of traumatic mesenteric avulsion. ( 0,581882123077654 )
Comput Math Methods Med - In vivo imaging-based mathematical modeling techniques that enhance the understanding of oncogene addiction in relation to tumor growth. ( 0,581636121994923 )
Med Biol Eng Comput - Clinically oriented real-time monitoring of the individual's risk for deep tissue injury. ( 0,581436403268755 )
Neural Comput - Molecular diffusion model of neurotransmitter homeostasis around synapses supporting gradients. ( 0,580325324616278 )
Comput Methods Programs Biomed - Determination of nonlinear fibre-reinforced biphasic poroviscoelastic constitutive parameters of articular cartilage using stress relaxation indentation testing and an optimizing finite element analysis. ( 0,57997075801837 )
J Med Syst - Post-operative assessment of an implant fixation in anterior cruciate ligament reconstructive surgery. ( 0,579915301436665 )
Comput. Biol. Med. - Maxwell's equations-based dynamic laser-tissue interaction model. ( 0,578237889421772 )
IEEE J Biomed Health Inform - Skin Temperature Prediction in Lower Limb Prostheses. ( 0,576369715973109 )
Comput Biol Chem - Self-organizing map of gene regulatory networks for cell phenotypes during reprogramming. ( 0,575575615281664 )
Int J Comput Assist Radiol Surg - Surgical stent planning: simulation parameter study for models based on DICOM standards. ( 0,575199642942975 )
Med Biol Eng Comput - Mathematical modeling of stem cell proliferation. ( 0,574930641616731 )
J Med Syst - Thermal shock resistance of skin tissue. ( 0,574468371352599 )
Comput Methods Programs Biomed - Drug release profile in core-shell nanofibrous structures: a study on Peppas equation and artificial neural network modeling. ( 0,574224427063947 )
Med Biol Eng Comput - Estimation of the retainer height biomechanical contribution in posterior resin-bonded fixed partial dentures: a structural-thermal coupled finite element analysis. ( 0,5731823714003 )
Med Biol Eng Comput - Biomechanical comparison of fusionless growth modulation corrective techniques in pediatric scoliosis. ( 0,573176424652232 )
Med Biol Eng Comput - Finite element analysis of idealised unit cell cancellous structure based on morphological indices of cancellous bone. ( 0,57254708505176 )
Comput Methods Programs Biomed - Prediction of coronary plaque location on arteries having myocardial bridge, using finite element models. ( 0,571760634341234 )
Med Biol Eng Comput - Effects of skin wrinkles, age and wetness on mechanical loads in the stratum corneum as related to skin lesions. ( 0,571678999208932 )
Int J Med Robot - The effect of proximal tibial corrective osteotomy on menisci, tibia and tarsal bones: a finite element model study of tibia vara. ( 0,571301751343751 )
Int J Comput Assist Radiol Surg - Evaluation of fetal tissue viscoelastic characteristics for robotic fetal surgery. ( 0,570691083846458 )
Comput. Biol. Med. - Accurate computation of traveling wavefronts in a biological hydrodynamic model. ( 0,569712213335487 )
Comput Math Methods Med - The influence of the specimen shape and loading conditions on the parameter identification of a viscoelastic brain model. ( 0,568741285672209 )
Comput. Biol. Med. - Experimental validation of 3D printed patient-specific implants using digital image correlation and finite element analysis. ( 0,567424762131984 )
Comput Math Methods Med - Comparative evaluation of osseointegrated dental implants based on platform-switching concept: influence of diameter, length, thread shape, and in-bone positioning depth on stress-based performance. ( 0,565665741553553 )
Med Biol Eng Comput - Validation efforts and flexibilities of an eight-year-old human juvenile lumbar spine using a three-dimensional finite element model. ( 0,564832596256306 )
Med Biol Eng Comput - Characterization of cellular elastic modulus using structure based double layer model. ( 0,564766885714276 )