Comput Math Methods Med - Simulation of intra-aneurysmal blood flow by different numerical methods.

Tópicos

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Resumo

The occlusional performance of sole endoluminal stenting of intracranial aneurysms is controversially discussed in the literature. Simulation of blood flow has been studied to shed light on possible causal attributions. The outcome, however, largely depends on the numerical method and various free parameters. The present study is therefore conducted to find ways to define parameters and efficiently explore the huge parameter space with finite element methods (FEMs) and lattice Boltzmann methods (LBMs). The goal is to identify both the impact of different parameters on the results of computational fluid dynamics (CFD) and their advantages and disadvantages. CFD is applied to assess flow and aneurysmal vorticity in 2D and 3D models. To assess and compare initial simulation results, simplified 2D and 3D models based on key features of real geometries and medical expert knowledge were used. A result obtained from this analysis indicates that a combined use of the different numerical methods, LBM for fast exploration and FEM for a more in-depth look, may result in a better understanding of blood flow and may also lead to more accurate information about factors that influence conditions for stenting of intracranial aneurysms.

Resumo Limpo

occlusion perform sole endolumin stent intracrani aneurysm controversi discuss literatur simul blood flow studi shed light possibl causal attribut outcom howev larg depend numer method various free paramet present studi therefor conduct find way defin paramet effici explor huge paramet space finit element method fem lattic boltzmann method lbms goal identifi impact differ paramet result comput fluid dynam cfd advantag disadvantag cfd appli assess flow aneurysm vortic d d model assess compar initi simul result simplifi d d model base key featur real geometri medic expert knowledg use result obtain analysi indic combin use differ numer method lbm fast explor fem indepth look may result better understand blood flow may also lead accur inform factor influenc condit stent intracrani aneurysm

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