Comput Math Methods Med - ADLD: a novel graphical representation of protein sequences and its application.

Tópicos

{ sequenc(1873) structur(1644) protein(1328) }
{ visual(1396) interact(850) tool(830) }
{ imag(2830) propos(1344) filter(1198) }
{ algorithm(1844) comput(1787) effici(935) }
{ analysi(2126) use(1163) compon(1037) }
{ imag(1947) propos(1133) code(1026) }
{ method(1219) similar(1157) match(930) }
{ state(1844) use(1261) util(961) }
{ structur(1116) can(940) graph(676) }
{ use(1733) differ(960) four(931) }
{ data(1737) use(1416) pattern(1282) }
{ motion(1329) object(1292) video(1091) }
{ framework(1458) process(801) describ(734) }
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{ estim(2440) model(1874) function(577) }
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{ method(1969) cluster(1462) data(1082) }
{ detect(2391) sensit(1101) algorithm(908) }

Resumo

To facilitate the intuitional analysis of protein sequences, a novel graphical representation of protein sequences called ADLD (Alignment Diagonal Line Diagram) is introduced in this paper first, and then a new ADLD based method is proposed and utilized to analyze the similarity/dissimilarity of protein sequences. Comparing with existing methods, our ADLD based method is proved to be effective in the similarity/dissimilarity analysis of protein sequences and have the merits of good intuition, visuality, and simplicity. The examinations of the similarities/dissimilarities for both the 16 different ND5 proteins and the 29 different spike proteins illustrate the utility of our ADLD based approach.

Resumo Limpo

facilit intuit analysi protein sequenc novel graphic represent protein sequenc call adld align diagon line diagram introduc paper first new adld base method propos util analyz similaritydissimilar protein sequenc compar exist method adld base method prove effect similaritydissimilar analysi protein sequenc merit good intuit visual simplic examin similaritiesdissimilar differ nd protein differ spike protein illustr util adld base approach

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