Comput Math Methods Med - A meshfree method for simulating myocardial electrical activity.

Tópicos

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Resumo

An element-free Galerkin method (EFGM) is proposed to simulate the propagation of myocardial electrical activation without explicit mesh constraints using a monodomain model. In our framework the geometry of myocardium is first defined by a meshfree particle representation that is, a sufficient number of sample nodes without explicit connectivities are placed in and inside the surface of myocardium. Fiber orientations and other material properties of myocardium are then attached to sample nodes according to their geometrical locations, and over the meshfree particle representation spatial variation of these properties is approximated using the shape function of EFGM. After the monodomain equations are converted to their Galerkin weak form and solved using EFGM, the propagation of myocardial activation can be simulated over the meshfree particle representation. The derivation of this solution technique is presented along a series of numerical experiments and a solution of monodomain model using a FitzHugh-Nagumo (FHN) membrane model in a canine ventricular model and a human-heart model which is constructed from digitized virtual Chinese dataset.

Resumo Limpo

elementfre galerkin method efgm propos simul propag myocardi electr activ without explicit mesh constraint use monodomain model framework geometri myocardium first defin meshfre particl represent suffici number sampl node without explicit connect place insid surfac myocardium fiber orient materi properti myocardium attach sampl node accord geometr locat meshfre particl represent spatial variat properti approxim use shape function efgm monodomain equat convert galerkin weak form solv use efgm propag myocardi activ can simul meshfre particl represent deriv solut techniqu present along seri numer experi solut monodomain model use fitzhughnagumo fhn membran model canin ventricular model humanheart model construct digit virtual chines dataset

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