Comput Math Methods Med - Dynamics analysis and simulation of a modified HIV infection model with a saturated infection rate.

Tópicos

{ model(3480) simul(1196) paramet(876) }
{ treatment(1704) effect(941) patient(846) }
{ take(945) account(800) differ(722) }
{ chang(1828) time(1643) increas(1301) }
{ imag(1947) propos(1133) code(1026) }
{ drug(1928) target(777) effect(648) }
{ activ(1138) subject(705) human(624) }
{ measur(2081) correl(1212) valu(896) }
{ algorithm(1844) comput(1787) effici(935) }
{ method(1557) propos(1049) approach(1037) }
{ general(901) number(790) one(736) }
{ spatial(1525) area(1432) region(1030) }
{ health(1844) social(1437) communiti(874) }
{ result(1111) use(1088) new(759) }
{ implement(1333) system(1263) develop(1122) }
{ method(1219) similar(1157) match(930) }
{ assess(1506) score(1403) qualiti(1306) }
{ problem(2511) optim(1539) algorithm(950) }
{ extract(1171) text(1153) clinic(932) }
{ data(1714) softwar(1251) tool(1186) }
{ howev(809) still(633) remain(590) }
{ data(3963) clinic(1234) research(1004) }
{ patient(2837) hospit(1953) medic(668) }
{ model(2656) set(1616) predict(1553) }
{ group(2977) signific(1463) compar(1072) }
{ data(3008) multipl(1320) sourc(1022) }
{ method(1969) cluster(1462) data(1082) }
{ method(2212) result(1239) propos(1039) }
{ detect(2391) sensit(1101) algorithm(908) }
{ model(3404) distribut(989) bayesian(671) }
{ can(774) often(719) complex(702) }
{ data(1737) use(1416) pattern(1282) }
{ inform(2794) health(2639) internet(1427) }
{ system(1976) rule(880) can(841) }
{ imag(1057) registr(996) error(939) }
{ bind(1733) structur(1185) ligand(1036) }
{ sequenc(1873) structur(1644) protein(1328) }
{ featur(3375) classif(2383) classifi(1994) }
{ imag(2830) propos(1344) filter(1198) }
{ network(2748) neural(1063) input(814) }
{ imag(2675) segment(2577) method(1081) }
{ patient(2315) diseas(1263) diabet(1191) }
{ studi(2440) review(1878) systemat(933) }
{ motion(1329) object(1292) video(1091) }
{ surgeri(1148) surgic(1085) robot(1054) }
{ framework(1458) process(801) describ(734) }
{ error(1145) method(1030) estim(1020) }
{ learn(2355) train(1041) set(1003) }
{ concept(1167) ontolog(924) domain(897) }
{ clinic(1479) use(1117) guidelin(835) }
{ design(1359) user(1324) use(1319) }
{ control(1307) perform(991) simul(935) }
{ model(2220) cell(1177) simul(1124) }
{ care(1570) inform(1187) nurs(1089) }
{ method(984) reconstruct(947) comput(926) }
{ search(2224) databas(1162) retriev(909) }
{ featur(1941) imag(1645) propos(1176) }
{ case(1353) use(1143) diagnosi(1136) }
{ studi(1410) differ(1259) use(1210) }
{ risk(3053) factor(974) diseas(938) }
{ perform(999) metric(946) measur(919) }
{ research(1085) discuss(1038) issu(1018) }
{ system(1050) medic(1026) inform(1018) }
{ import(1318) role(1303) understand(862) }
{ model(2341) predict(2261) use(1141) }
{ visual(1396) interact(850) tool(830) }
{ compound(1573) activ(1297) structur(1058) }
{ perform(1367) use(1326) method(1137) }
{ studi(1119) effect(1106) posit(819) }
{ blood(1257) pressur(1144) flow(957) }
{ record(1888) medic(1808) patient(1693) }
{ health(3367) inform(1360) care(1135) }
{ monitor(1329) mobil(1314) devic(1160) }
{ ehr(2073) health(1662) electron(1139) }
{ state(1844) use(1261) util(961) }
{ research(1218) medic(880) student(794) }
{ data(2317) use(1299) case(1017) }
{ age(1611) year(1155) adult(843) }
{ medic(1828) order(1363) alert(1069) }
{ signal(2180) analysi(812) frequenc(800) }
{ cost(1906) reduc(1198) effect(832) }
{ sampl(1606) size(1419) use(1276) }
{ gene(2352) biolog(1181) express(1162) }
{ first(2504) two(1366) second(1323) }
{ intervent(3218) particip(2042) group(1664) }
{ time(1939) patient(1703) rate(768) }
{ patient(1821) servic(1111) care(1106) }
{ use(2086) technolog(871) perceiv(783) }
{ can(981) present(881) function(850) }
{ analysi(2126) use(1163) compon(1037) }
{ structur(1116) can(940) graph(676) }
{ high(1669) rate(1365) level(1280) }
{ cancer(2502) breast(956) screen(824) }
{ use(976) code(926) identifi(902) }
{ use(1733) differ(960) four(931) }
{ survey(1388) particip(1329) question(1065) }
{ estim(2440) model(1874) function(577) }
{ decis(3086) make(1611) patient(1517) }
{ process(1125) use(805) approach(778) }
{ activ(1452) weight(1219) physic(1104) }

Resumo

This paper studies a modified human immunodeficiency virus (HIV) infection differential equation model with a saturated infection rate. It is proved that if the basic virus reproductive number R 0 of the model is less than one, then the infection-free equilibrium point of the model is globally asymptotically stable; if R 0 of the model is more than one, then the endemic infection equilibrium point of the model is globally asymptotically stable. Based on the clinical data from HIV drug resistance database of Stanford University, using the proposed model simulates the dynamics of the two groups of patients' anti-HIV infection treatment. The numerical simulation results are in agreement with the evolutions of the patients' HIV RNA levels. It can be assumed that if an HIV infected individual's basic virus reproductive number R 0 < 1 then this person will recover automatically; if an antiretroviral therapy makes an HIV infected individual's R 0 < 1, this person will be cured eventually; if an antiretroviral therapy fails to suppress an HIV infected individual's HIV RNA load to be of unpredictable level, the time that the patient's HIV RNA level has achieved the minimum value may be the starting time that drug resistance has appeared.

Resumo Limpo

paper studi modifi human immunodefici virus hiv infect differenti equat model satur infect rate prove basic virus reproduct number r model less one infectionfre equilibrium point model global asymptot stabl r model one endem infect equilibrium point model global asymptot stabl base clinic data hiv drug resist databas stanford univers use propos model simul dynam two group patient antihiv infect treatment numer simul result agreement evolut patient hiv rna level can assum hiv infect individu basic virus reproduct number r person will recov automat antiretrovir therapi make hiv infect individu r person will cure eventu antiretrovir therapi fail suppress hiv infect individu hiv rna load unpredict level time patient hiv rna level achiev minimum valu may start time drug resist appear

Resumos Similares

Comput Math Methods Med - Analytical solutions for the mathematical model describing the formation of liver zones via Adomian's method. ( 0,876002671089167 )
Comput. Biol. Med. - ODE/PDE analysis of corneal curvature. ( 0,840015890308058 )
Comput Biol Chem - An efficient nonlinear finite-difference approach in the computational modeling of the dynamics of a nonlinear diffusion-reaction equation in microbial ecology. ( 0,836909856547384 )
J Integr Bioinform - An advanced environment for hybrid modeling of biological systems based on modelica. ( 0,836635746241702 )
Brief. Bioinformatics - Choosing appropriate models for protein-protein interaction networks: a comparison study. ( 0,830051678475355 )
Neural Comput - Effect of phase response curve skewness on synchronization of electrically coupled neuronal oscillators. ( 0,829943458440985 )
Comput Math Methods Med - Modeling schistosomiasis and HIV/AIDS codynamics. ( 0,826079770291735 )
Comput Math Methods Med - Solutions of a linearized mathematical model for capillary formation in tumor angiogenesis: an initial data perturbation approximation. ( 0,808972693063033 )
Med Biol Eng Comput - CSF dynamic analysis of a predictive pulsatility-based infusion test for normal pressure hydrocephalus. ( 0,805718413335122 )
Comput Methods Programs Biomed - Functionality of the baroreceptor nerves in heart rate regulation. ( 0,804808602231303 )
Comput Math Methods Med - Global hopf bifurcation on two-delays leslie-gower predator-prey system with a prey refuge. ( 0,799299987627221 )
Comput. Biol. Med. - Modeling multiple experiments using regularized optimization: A case study on bacterial glucose utilization dynamics. ( 0,794719183406478 )
Comput Math Methods Med - Numerical solutions for a model of tissue invasion and migration of tumour cells. ( 0,79144654231693 )
Comput Math Methods Med - Computational modeling of microabscess formation. ( 0,785256238912882 )
Neural Comput - Analytical integrate-and-fire neuron models with conductance-based dynamics and realistic postsynaptic potential time course for event-driven simulation strategies. ( 0,783735097924364 )
IEEE Trans Image Process - Efficiency of semi-implicit schemes for anisotropic diffusion in the hypercube. ( 0,779497436243155 )
Neural Comput - Cross-talk induces bifurcations in nonlinear models of synaptic plasticity. ( 0,772054549764138 )
Comput Methods Programs Biomed - Development of a computer algorithm for feedback controlled electrical nerve fiber stimulation. ( 0,77011688125507 )
J Clin Monit Comput - The standard strong ion difference, standard total titratable base, and their relationship to the Boston compensation rules and the Van Slyke equation for extracellular fluid. ( 0,768468089338563 )
Comput Math Methods Med - Modeling innate immune response to early Mycobacterium infection. ( 0,762274736893069 )
Comput Math Methods Med - A theoretical model for the transmission dynamics of the Buruli ulcer with saturated treatment. ( 0,760571317560383 )
J. Comput. Biol. - Is an intuitive convergence definition of molecular dynamics simulations solely based on the root mean square deviation possible? ( 0,76021149830438 )
Comput Math Methods Med - ModeLang: a new approach for experts-friendly viral infections modeling. ( 0,76008956290544 )
Comput. Biol. Med. - Modelling and simulating reaction-diffusion systems using coloured Petri nets. ( 0,759927149631645 )
Comput Methods Programs Biomed - Reprint of Pharmacokinetic modelling of the anti-malarial drug artesunate and its active metabolite dihydroartemisinin. ( 0,759266551804141 )
J Chem Inf Model - Full and partial agonism of ionotropic glutamate receptors indicated by molecular dynamics simulations. ( 0,757066839440024 )
Comput Math Methods Med - Numerical stability of partitioned approach in fluid-structure interaction for a deformable thin-walled vessel. ( 0,756033595247557 )
Med Biol Eng Comput - A fluid-structure interaction model of the aortic valve with coaptation and compliant aortic root. ( 0,753516256834278 )
Comput. Biol. Med. - Network and Nakamura tridiagonal computational simulation of electrically-conducting biopolymer micro-morphic transport phenomena. ( 0,75236298243821 )
Comput. Biol. Med. - Numerical investigation into blood clotting at the bone-dental implant interface in the presence of an electrical stimulus. ( 0,751386280385097 )
Comput Math Methods Med - Uncertainty quantification in simulations of epidemics using polynomial chaos. ( 0,744851405523889 )
Neural Comput - Computing confidence intervals for point process models. ( 0,744226954299478 )
Comput Math Methods Med - Mathematical modeling of transmission dynamics and optimal control of vaccination and treatment for hepatitis B virus. ( 0,738301179204111 )
Comput Math Methods Med - Complexity analysis and parameter estimation of dynamic metabolic systems. ( 0,734941467742057 )
Comput. Biol. Med. - Examples of testing global identifiability of biological and biomedical models with the DAISY software. ( 0,734743721564849 )
Wiley Interdiscip Rev Syst Biol Med - A conceptual framework for computational models of Achilles tendon homeostasis. ( 0,733825627483605 )
Comput. Biol. Med. - Mathematical modeling of brain glioma growth using modified reaction-diffusion equation on brain MR images. ( 0,733451097673746 )
Comput Methods Programs Biomed - An efficient passive planar micromixer with ellipse-like micropillars for continuous mixing of human blood. ( 0,732624136418338 )
Comput. Biol. Med. - A compartment model of alveolar-capillary oxygen diffusion with ventilation-perfusion gradient and dynamics of air transport through the respiratory tract. ( 0,726496569416076 )
Comput Biol Chem - A stochastic evolution model for residue Insertion-Deletion Independent from Substitution. ( 0,724519117203923 )
Comput Biol Chem - Parameter sensitivity analysis of stochastic models: application to catalytic reaction networks. ( 0,719664877575595 )
Comput Math Methods Med - Towards patient-specific modeling of coronary hemodynamics in healthy and diseased state. ( 0,715917105441771 )
Lifetime Data Anal - Bayesian dynamic regression models for interval censored survival data with application to children dental health. ( 0,714162098550268 )
Comput. Biol. Med. - Computing the stability of steady-state solutions of mathematical models of the electrical activity in the heart. ( 0,712940626883133 )
Comput Math Methods Med - A mathematical study of a TB Model with treatment interruptions and two latent periods. ( 0,71175366180914 )
Comput. Biol. Med. - Phase lagging model of brain response to external stimuli-modeling of single action potential. ( 0,710751935877524 )
Comput. Biol. Med. - epiModel: a system to build automatically systems of differential equations of compartmental type-epidemiological models. ( 0,708054575346527 )
Comput Math Methods Med - Noninvasive monitoring of hepatic damage from hepatitis C virus infection. ( 0,706162415599848 )
Comput Methods Programs Biomed - Solving delay differential equations in S-ADAPT by method of steps. ( 0,697517021751539 )
Neural Comput - Active data collection for efficient estimation and comparison of nonlinear neural models. ( 0,697083196439066 )
IEEE Trans Image Process - Additive log-logistic model for networked video quality assessment. ( 0,696524767898203 )
Comput Math Methods Med - Dynamics of Mycobacterium and bovine tuberculosis in a human-buffalo population. ( 0,694238585152651 )
Lifetime Data Anal - An extended cure model and model selection. ( 0,69396105622485 )
Comput Biol Chem - A state-time epidemiology model of tuberculosis: importance of re-infection. ( 0,69103424224765 )
Wiley Interdiscip Rev Syst Biol Med - Influenza A virus infection kinetics: quantitative data and models. ( 0,69055925934702 )
IEEE Trans Image Process - Fast cartoon + texture image filters. ( 0,690549155215615 )
Comput. Biol. Med. - An implicit evolution scheme for active contours and surfaces based on IIR filtering. ( 0,687097379293705 )
Comput Methods Programs Biomed - A therapy parameter-based model for predicting blood glucose concentrations in patients with type 1 diabetes. ( 0,686313172911551 )
Comput. Biol. Med. - Semi-computational simulation of magneto-hemodynamic flow in a semi-porous channel using optimal homotopy and differential transform methods. ( 0,685951840557235 )
Brief. Bioinformatics - Investigating biocomplexity through the agent-based paradigm. ( 0,683906777619037 )
Comput Methods Programs Biomed - Design of a framework for modeling, integration and simulation of physiological models. ( 0,682569878726173 )
J Clin Monit Comput - Simulating physiological interactions in a hybrid system of mathematical models. ( 0,674851514338763 )
Comput Math Methods Med - A mathematical model of cancer treatment by radiotherapy. ( 0,673872566915752 )
IEEE Trans Pattern Anal Mach Intell - Bi-polynomial Modeling of Low-frequency Reflectances. ( 0,671946514091107 )
IEEE J Biomed Health Inform - Prediction of Hemodynamic Response to Epinephrine via Model-Based System Identification. ( 0,671015356547114 )
Comput Math Methods Med - Disease control of delay SEIR model with nonlinear incidence rate and vertical transmission. ( 0,668916967138163 )
Comput Math Methods Med - A numerical method of reduced complexity for simulating vascular hemodynamics using coupled 0D lumped and 1D wave propagation models. ( 0,668874455307421 )
IEEE Trans Vis Comput Graph - Paraglide: Interactive Parameter Space Partitioning for Computer Simulations. ( 0,668852459016393 )
J Chem Inf Model - Fitting of dihedral terms in classical force fields as an analytic linear least-squares problem. ( 0,668027938557177 )
Comput. Biol. Med. - Simulated temperature distribution of the proximal forearm. ( 0,666349381581229 )
AMIA Annu Symp Proc - Simulation Analysis Platform (SnAP): a tool for evaluation of public health surveillance and disease control strategies. ( 0,664358867601533 )
IEEE Trans Neural Netw Learn Syst - Global exponential synchronization of multiple memristive neural networks with time delay via nonlinear coupling. ( 0,662038846680742 )
Comput Biol Chem - Stochastic synchronization of interacting pathways in testosterone model. ( 0,661636211436367 )
Comput Methods Programs Biomed - Biomechanical analyses of static and dynamic fixation techniques of retrograde interlocking femoral nailing using nonlinear finite element methods. ( 0,661179604907286 )
Neural Comput - An investigation of the stochastic Hodgkin-Huxley models under noisy rate functions. ( 0,660862353571401 )
Comput. Biol. Med. - Model-based assessment of baroreflex and cardiopulmonary couplings during graded head-up tilt. ( 0,660357314949906 )
Comput Math Methods Med - Optimal control of HIV/AIDS in the workplace in the presence of careless individuals. ( 0,659685892748371 )
Comput Methods Programs Biomed - Parametric-based brain Magnetic Resonance Elastography using a Rayleigh damping material model. ( 0,659202180159928 )
Comput Methods Programs Biomed - Modelling the Double Peak Phenomenon in pharmacokinetics. ( 0,656579423346569 )
Neural Comput - Synchronization of stochastic competitive neural networks with different timescales and reaction-diffusion terms. ( 0,651670169998873 )
Neural Comput - MOSAIC for multiple-reward environments. ( 0,648140481079352 )
Comput Methods Programs Biomed - Simulating and analysing infectious disease data in a heterogeneous population with migration. ( 0,645544841259306 )
Comput Methods Programs Biomed - Automatically designed machine vision system for the localization of CCA transverse section in ultrasound images. ( 0,644691792313644 )
Comput Methods Programs Biomed - Computation of restoration of ligand response in the random kinetics of a prostate cancer cell signaling pathway. ( 0,64274069016029 )
Comput Methods Programs Biomed - System approach to modeling of liver glucose metabolism with physiologically interpreted model parameters outgoing from [18F]FDG concentrations measured by PET. ( 0,64210510562466 )
Comput Methods Programs Biomed - Epithelial to mesenchymal transition-the roles of cell morphology, labile adhesion and junctional coupling. ( 0,641313819094913 )
Comput Methods Programs Biomed - Kinetic modelling of the role of the aldehyde dehydrogenase enzyme and the breast cancer resistance protein in drug resistance and transport. ( 0,640565348463242 )
Comput Math Methods Med - Spongiosa primary development: a biochemical hypothesis by Turing patterns formations. ( 0,639510799718798 )
Int J Neural Syst - A generalized Leaky Integrate-and-Fire neuron model with fast implementation method. ( 0,638262254158605 )
Comput Math Methods Med - Comparing statistical models to predict dengue fever notifications. ( 0,637760995591241 )
Med Biol Eng Comput - An improved curvilinear gradient method for parameter optimization in complex biological models. ( 0,631861699962795 )
Wiley Interdiscip Rev Syst Biol Med - Glass-like dynamics in the cell and in cellular collectives. ( 0,630617336565451 )
Comput Methods Programs Biomed - Innovative model to simulate exhalation phase in human respiratory system. ( 0,629663951735345 )
Med Biol Eng Comput - Experimental validation of quasi-one-dimensional and two-dimensional steady glottal flow models. ( 0,629541247005422 )
Comput. Biol. Med. - On a reusable and multilevel methodology for modeling and simulation of pharmacokinetic-physiological systems: a preliminary study. ( 0,628928487286134 )
Neural Comput - Dynamical movement primitives: learning attractor models for motor behaviors. ( 0,625945080821312 )
Neural Comput - A principled dimension-reduction method for the population density approach to modeling networks of neurons with synaptic dynamics. ( 0,625670877050865 )
Comput Methods Programs Biomed - Comparison of interval and Monte Carlo simulation for the prediction of postprandial glucose under uncertainty in type 1 diabetes mellitus. ( 0,62561665035433 )
Comput Math Methods Med - Discrete-state stochastic models of calcium-regulated calcium influx and subspace dynamics are not well-approximated by ODEs that neglect concentration fluctuations. ( 0,625585823137713 )
IEEE Trans Image Process - Reinitialization-free level set evolution via reaction diffusion. ( 0,624921368509145 )