Comput Math Methods Med - Multiscale cross-approximate entropy analysis as a measurement of complexity between ECG R-R interval and PPG pulse amplitude series among the normal and diabetic subjects.

Tópicos

{ signal(2180) analysi(812) frequenc(800) }
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{ error(1145) method(1030) estim(1020) }
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Resumo

Physiological signals often show complex fluctuation (CF) under the dual influence of temporal and spatial scales, and CF can be used to assess the health of physiologic systems in the human body. This study applied multiscale cross-approximate entropy (MC-ApEn) to quantify the complex fluctuation between R-R intervals series and photoplethysmography amplitude series. All subjects were then divided into the following two groups: healthy upper middle-aged subjects (Group 1, age range: 41-80 years, n = 27) and upper middle-aged subjects with type 2 diabetes (Group 2, age range: 41-80 years, n = 24). There are significant differences of heart rate variability, LHR, between Groups 1 and 2 (1.94 ? 1.21 versus 1.32 ? 1.00, P = 0.031). Results demonstrated differences in sum of large scale MC-ApEn (MC-ApEn(LS)) (5.32 ? 0.50 versus 4.74 ? 0.78, P = 0.003). This parameter has a good agreement with pulse-pulse interval and pulse amplitude ratio (PAR), a simplified assessment for baroreflex activity. In conclusion, this study employed the MC-ApEn method, integrating multiple temporal and spatial scales, to quantify the complex interaction between the two physical signals. The MC-ApEn(LS) parameter could accurately reflect disease process in diabetics and might be another way for assessing the autonomic nerve function.

Resumo Limpo

physiolog signal often show complex fluctuat cf dual influenc tempor spatial scale cf can use assess health physiolog system human bodi studi appli multiscal crossapproxim entropi mcapen quantifi complex fluctuat rr interv seri photoplethysmographi amplitud seri subject divid follow two group healthi upper middleag subject group age rang year n upper middleag subject type diabet group age rang year n signific differ heart rate variabl lhr group versus p result demonstr differ sum larg scale mcapen mcapenl versus p paramet good agreement pulsepuls interv puls amplitud ratio par simplifi assess baroreflex activ conclus studi employ mcapen method integr multipl tempor spatial scale quantifi complex interact two physic signal mcapenl paramet accur reflect diseas process diabet might anoth way assess autonom nerv function

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